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Although more research is needed, there is mounting evidence that cannabis can help patients suffering from insomnia and sleep disturbances. Every patient is unique, so at Green Bridge Health, we help each patient find the best cannabis regimen for them through one-on-one consultations. If you would like to schedule a medical cannabis consultation, please go to our website: Green Bridge Health.com and make an appointment to meet with one of our experienced medical professionals. We look forward to helping guide you on your cannabis journey back to health. For more information: greenbridgehealth.com To schedule an appointment: https://greenbridgehealthscheduling.as.me/ To get your MMJ Card: greenbridgesociety.com or Call (814) 360 5353 Welcome to the Green Bridge minute brought to you by Green Bridge Health and Green Bridge Society. My name is doctor Gerald Knepp. According to the American Sleep Association, 50 to 70 million adults in the United States suffer from a sleep disorder. Insomnia is the most common sleep disorder, 10% of adults report having chronic insomnia, and approximately 30% report having short term issues. Cannabis has been used to aid with sleep for thousands of years. In ancient India, cannabis was used to treat insomnia, and in ancient China, as early as 200CE, a mixture of wine and cannabis was used as an anesthetic before surgery. Early on, the effects of cannabis on sleep were reported in Western medical literature. In the 1860’s, the German physician Bernard Fronmuller tested the effects of “Indian hemp” in 1,000 patients with sleep disturbance, 53% of the patients reported a curative effect and over 21% experienced a partial cure Much more recently, in 2019, a study was published in the journal of Psychoactive drugs where researchers surveyed 1,000 dispensary customers in Colorado. 74% of those surveyed reported using cannabis to improve sleep. Of those using cannabis for sleep, 84% found it very or extremely helpful, and many of those patients reported stopping the use of prescription and OTC sleep medications. We see similar trends in the medical cannabis states. Although sleep disorders are not approved conditions for many medical cannabis programs, many patients report using cannabis to help improve sleep. Many of our patients suffering from anxiety, PTSD, chronic pain, and cancer also have trouble falling and staying asleep. Let’s look at some of the literature surrounding cannabis and sleep. The Endocannabinoid system, which is composed of endogenous cannabinoids and receptors, regulates dozens of processes within the human body, so it is no surprise that it impacts sleep too. The Endocannabinoid system is involved in the regulation of the circadian sleep–wake cycle including the promotion of sleep. Phytocannabinoids are cannabinoids that are found in the cannabis plant. THC and CBD are the most prominent phytocannabinoids found in cannabis. THC or Tetrahydrocannabinol may help patients fall asleep faster. A small trial compared different doses of THC in insomnia patients. The 20 mg dose produced the best results in reducing the time needed to fall asleep. The average improvement was 62 minutes faster than placebo. THC seems to help with obstructive sleep apnea as well. Dronabinol is a synthetic version of THC, and it was used in a sleep apnea study reported in 2016. The study compared a placebo, a 2.5mg dose, and a 10mg dose. These were taken 1 hour before bedtime for 6 weeks. The 10mg dose reduced the apnea-hypopnea index by approximately 50% and produced the highest ratings of treatment satisfaction. In my experience, cannabis seems to be most effective in treating sleep disturbances in patients with comorbidities known to be helped by cannabis, such as chronic pain, anxiety, and restless leg syndrome. And the scientific literature supports this too. Nabilone, another synthetic form of THC, was shown to improve sleep in patients with chronic pain, including patients with diabetic peripheral neuropathic pain and chronic noncancer pain. We see quite a few larger studies looking at synthetic THC drugs like Nabilone and Dronabinol, since they are funded by pharmaceutical companies. If you would like to schedule a medical cannabis consultation, please go to our website: Green Bridge Health.com and make an appointment to meet with one of our experienced medical professionals. We look forward to helping guide you on your cannabis journey back to health.

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