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Delta 8 THC Compared to Delta 9 THC
Professor DeBacco
Delta-9 THC Explained
As an activator of the CB1 receptor, delta-9-tetrahydrocannabinol — commonly known as THC is the main intoxicating component of cannabis.
THC intoxication has been shown to increase blood flow to the prefrontal cortex, the region of the brain responsible for decision-making, attention, motor skills, and other executive functions.
When THC binds to CB1 receptors in the brain's reward system, it can trigger feelings of euphoria.
Much of THC's ability to relieve pain is due to its interaction with CB1 receptors in the midbrain.
Delta-8 THC Explained
Delta-8-THC is an isomer of Delta-9 THC
It only differs from delta-9-THC by the placement of one atomic double bond.
Generally, this chemical is produced in a lab, not extracted directly from the plant. It is actually synthesized from CBD Isolate.
This creates a legal loophole, because the product is being sold as “hemp derived” even though it is actually a chemically produced THC isomer.
Extraction Difference
Delta 9 THC is a major cannabinoid that can be found in abundance and is easily extracted from in cannabis.
Extracting Delta 8 THC is more challenging because it is a minor cannabinoid
Synthesizing Delta 8 from CBD
Delta 8 can be synthesized entirely from CBD with the use of solvents.
Deriving Delta 8 from hemp ensures the final product is under the 0.3% THC level to be federally legal.
Steps to Synthesize D8 THC from CBD isolate
Dissolve into non-polar solvent of choice. Common solvents include heptane.
Add a Lewis acid, like alumina, p-toluenesulfonic, or hydrochloric. Maintain the mixture at a temperature of 100 degrees C while continually stirring for upwards of 18 hours.
Once the chemical reaction is complete, and the upper phase is separated, wash and neutralize the solution with 5% NaHCO3
Test for purity and contaminants using HPLC, separate the converted mixture into its “many cannabinoid parts”.
Conversion is never 100%
Different Effects
Delta 9 is considerably more potent effects than Delta 8.
Ex. paranoid delusions, mental fog, impaired motor skills, and increased feelings of anxiety.
Delta 8 is reported to provide a more muted experience with most users feel a great sense of calm and clarity. However, many have reported a definite “high” to the experience, but not enough to impair the ability to form coherent thoughts or focus on activities.
Onset Time Difference
Delta 9 has an onset that is more rapid and instantaneous
Delta 8 works slowly and gradually as it eases users into a more mellow state
Similar End Products
Both can be smoked as a flower, inhaled through vaping, consumed in edible form also with a wide variety of topicals, capsules, tinctures, edibles and other products.
Legality
Delta 9 THC in any amount over 0.3% is not legal at a federal level.
State level depends entirely on their local laws.
Delta 8 is still technically legal on a federal level. That's because of the ambiguities of the 2018 Farm Bill, which legalized hemp production.
There is nothing within the bill that prohibits deriving Delta 8 from hemp and creating products with the compound.
Hazy Area
The psychoactive nature of Delta 8 has prompted a fair number of bans at the state level, though.
Currently there are 15 states that restrict the sale and use of Delta 8 products, with another 6 states where legal action is pending.
So while Delta 8 is more widespread at the moment than Delta 9, how long that will last has yet to be determined.
Availability
Delta 8 since it is federally legal can be shipped across state lines, unlike Delta 9.
There are a lot more online retailers for Delta 8 products as a result.
Remember: Delta 8 products are not regulated by the FDA, so it is up to you to seek out lab results tested from a third party lab.
Delta 9 vs Delta 8
Delta 9 might be considered the “classic” choice by some within the cannabis community,
Delta 8 has been quickly gaining in popularity due to its milder effects and legal availability.
Since this is an isomer of Delta 9 it is also likely to come under some form of regulation in the future even though that may not currently be the case.
Link to Lecture Slides: https://drive.google.com/file/d/1bTA2zy0R_dAN7zVTCzp0_XImiOmyHGlx/view?usp=sharing
*Due to the description character limit the full work cited for "Delta 8 THC Compared to Delta 9 THC" can be viewed at... https://drive.google.com/file/d/1ET_IIIsXWyUZ_FuID5oXLumMOchlYSzr/view?usp=sharing
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Kaum eine andere drogenpolitische Frage beschäftigt die Politik häufiger als die Cannabis-Legalisierung. Über ein Drittel der Schweizer Bevölkerung hat bereits einmal im Leben Marihuana probiert – und dies grundsätzlich illegal. Eine mögliche Legalisierung ist mittlerweile jedoch mehr als wilder Kiffer-Klatsch – Politik, Aktivistinnen und Wissenschaft gehen Hand in Hand, um eine mögliche Regulierung zu testen. Darum geht’s in der Reportage: 00:00 Intro 00:30 Soll man Cannabis legalisieren? 01:18 Wie sieht die rechtliche Lage aus? 01:49 Auf der Plantage 07:03 Pilotprojekt Social Clubs 09:54 Risiken einer Legalisierung 10:10 Wann kommt die Legalisierung? 13:49 Wrap up ▪️ Redaktion SRF Impact: Livio Carlin, Danae Fischer, Linus van Moorsel ▪️ Realisation: Bilder und Freunde ▪️ Stv. Leitung: Olivia Gähwiler, Lena Oppong Im Auftrag von ©2022 SRF ➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖ 🔔 JEDEN MITTWOCH UM 17.00 UHR EINE NEUE REPORTAGE ➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖➖ SRF Impact auf YouTube abonnieren 📍 https://www.youtube.com/c/srfimpact SRF Impact auf Instagram 📸 https://www.instagram.com/srfimpact SRF Impact auf srf.ch 👉 https://www.srf.ch .................................................................................. So abgefuckt und vielschichtig sie auch ist, wir wollen die Welt verstehen und schauen hin. Dafür machen wir Reportagen und zeigen, was echt passiert. .................................................................................. Social Media Netiquette von SRF: ▪️ https://srf.ch/social-netiquette #SRFImpact #Reportage #Cannabis
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INTRO TO CBD OIL 01:08 What is CBD Oil? 01:27 Hemp vs Marijuana 02:43 What does CBD do? 04:19 CBD as medicine? 04:55 Studies on CBD? 06:27 Is CBD Safe? 06:57 Is CBD Legal? 08:28 Picking a CBD oil? Types of products? 12:13 Checklist for buying CBD 14:00 Best brands 15:04 Make drug screen postive? LINKS TO STUDIES ON CBD: CBD in addiction - https://www.ncbi.nlm.nih.gov/pubmed/26269227 CBD in insomnia - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326553/ CBD for anxiety - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604171/ CBD in depression - https://www.ncbi.nlm.nih.gov/pubmed/24923339 CBD in pain - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690292/ CBD to quit smoking - https://www.ncbi.nlm.nih.gov/pubmed/29714034 CBD for Alzheimer's - https://www.ncbi.nlm.nih.gov/pubmed/27471947 CBD Safety Studies: https://www.ncbi.nlm.nih.gov/pubmed/31053391 https://www.ncbi.nlm.nih.gov/pubmed/22129319 https://www.ncbi.nlm.nih.gov/pubmed/28861514 Interaction with warfarin: https://www.ncbi.nlm.nih.gov/pubmed/29387536 Interaction with seizure meds: https://www.ncbi.nlm.nih.gov/pubmed/28782097 Kid that accidentally got high off CBD oil that was mislabeled: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043219/ FDA Survey of Online CBD products and mislabeling: https://jamanetwork.com/journals/jama/fullarticle/2661569 MAYO clinic overview of CBD oils (GREAT!) https://www.mayoclinicproceedings.org/article/S0025-6196(19)30007-2/fulltext Study on endocannabinoid system: https://www.ncbi.nlm.nih.gov/pubmed/16968947 DISCLAIMER*** Post Script provides informal, subjective information about medicines, labs, and medical topics. The views on this YouTube video are opinions and do not reflect any organizations or companies. The information provided is accurate and true to the best of the author’s knowledge, but there may be omissions and errors. Post Script is for entertainment and informational purposes only and does not provide medical advice, diagnosis, or treatment. Although the author of Post Script is a medical doctor, readers should not rely on the information on this video for their own health or medical care and should consult a medical professional before taking any sort of action. #cbd
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