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Counterfeit Weight Loss Drugs Exposed | GMP Risks & How to Ensure Patient Safety @HelpMeGMP Counterfeit weight loss drugs are flooding the market, putting patient safety at serious risk. But how do these fake medicines bypass regulatory controls, and what role does Good Manufacturing Practice (GMP) play in preventing them? In this video, we uncover the dangers of counterfeit pharmaceuticals, the risks associated with unauthorized GLP-1 receptor agonists like Ozempic, Wegovy, and Saxenda, and how GMP regulations help ensure drug safety and efficacy. 🔹 What You’ll Learn in This Video: ✔ The rise of counterfeit weight loss drugs in the pharmaceutical industry ✔ How counterfeit drugs make it into supply chains despite regulatory controls ✔ Real-world case studies of counterfeit Ozempic and Wegovy circulating globally ✔ The GMP failures that allow counterfeit medicines to enter the market ✔ The role of Good Distribution Practice (GDP) in maintaining drug supply chain integrity ✔ How regulatory agencies like the MHRA, FDA, and EMA combat counterfeit drugs ✔ The dangers of unlicensed weight loss injections and black-market pharmaceuticals ✔ How patients and healthcare professionals can verify the authenticity of medicines ✔ What pharmaceutical companies must do to strengthen supply chain security 🔹 Who Should Watch This Video? ✔ Healthcare professionals prescribing weight loss medications ✔ Pharmacists ensuring drug authenticity and patient safety ✔ Regulatory Affairs and Quality Assurance professionals working in GMP compliance ✔ Patients concerned about counterfeit drugs and medication safety ✔ Pharma supply chain and distribution professionals working in GDP compliance ✔ Anyone in the pharmaceutical industry looking to understand counterfeit drug risks 🔹 Key GMP & GDP Topics Covered: 📌 How counterfeit weight loss drugs bypass regulations 📌 What is Good Manufacturing Practice (GMP), and how does it prevent counterfeits? 📌 The role of Good Distribution Practice (GDP) in pharmaceutical supply chain security 📌 How counterfeit drugs impact patient safety and public health 📌 Steps pharmaceutical companies must take to avoid fake drugs entering the market 📌 How to verify the authenticity of prescription medicines 📌 Case studies: Ozempic, Wegovy, and other weight loss drugs in the counterfeit market 📌 How regulatory agencies investigate and take action against counterfeiters 🔹 Additional GMP & Regulatory Resources: 📌 [Link to GMP Guidelines for Drug Safety] 📌 [Link to MHRA & FDA Alerts on Counterfeit Drugs] 📌 [Link to GDP Compliance for Pharmaceutical Supply Chains] 🔹 Want More GMP & Pharma Compliance Training? At @HelpMeGMP, we provide FREE training on GMP, GDP, Quality Assurance, and Regulatory Compliance. Whether you're new to the industry or an experienced professional, our content is designed to help you stay ahead. 📢 Subscribe now for expert GMP insights: [Insert Subscription Link] 🔹 Connect with Us: 🌐 Visit our website: www.helpmegmp.com 📌 Follow us on LinkedIn: [Help Me GMP LinkedIn] 📩 Contact us for GMP training and career guidance #CounterfeitDrugs #GMPCompliance #WeightLossDrugs #PharmaceuticalSafety #Ozempic #Wegovy #GoodManufacturingPractice #GDPTraining #MHRA #FDA #PharmaQA #HelpMeGMP

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Holly Lofton, MD, an obesity expert at NYU Langone Health, discusses the differences between GLP-1 agonists for weight loss and glycemic control. https://www.medscape.com/viewarticle/995911?src=soc_yt -TRANSCRIPT- I'm Dr Holly Lofton, clinical associate professor of surgery and medicine at NYU Langone Health, and I direct the medical weight management program. My practice is solely based on chronic weight management for adults. Today I'll talk about the various doses of GLP-1 agonists that you may prescribe to your patients. Being that this is based around weight management, I'll start with the weight management medications, the first of which is Saxenda. This is liraglutide 3 mg for chronic weight management. The studies that were done with this medication were intended to get the patient to the 3-mg dosing, which is what's prescribed for weight management, and not the 1.8-mg dosing which is prescribed for type 2 diabetes. However, you may deliver different doses to your patients depending on your goal. You see that this makes a lot of clicking noise. When the patient starts Saxenda and has their pen, there will be this clear fluid. It's important to remind them that this is a multiuse pen and that they should use it over and over again until it's empty. This medication has various doses in the same pen. You want to increase weekly as long as the patient is tolerating it. And by that, I mean not having significant side effects such as nausea, constipation, or other stool changes. When a patient receives the pen, it will start with 0. In the first week, we do 0.6 mg daily. The next week we do 1.2 mg daily. The third week we do 1.8 mg daily. The next week we do 2.4 mg daily, and then the goal is to get the patient to 3 mg, which is the maintenance dose. Ideally, the patient would stay there for their chronic weight management. However, if a patient can't tolerate the dose, you can also have them go to a lower dose for 7 more days and try again. Wegovy, which is semaglutide 2.4 mg, is also prescribed for chronic weight management. This is a single-use cartridge, so the pen will deliver only the dose that you prescribe to the patient. This as well is intended to increase monthly as long as the patient is tolerating it and not having too many significant GI side effects such as nausea, constipation, or loose stool. With this pen, the doses are 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and 2.4 mg. You increase it monthly or every 4 weeks, depending on the patient tolerance. However, if a patient is not able to tolerate the highest dose, you can prescribe the maximally tolerated dose for that patient. The next new GLP-1 I'll talk about is Ozempic [semaglutide] prescribed for type 2 diabetes. The goals of titrating this medication really depend more on your patient's glycemic control, as this is used for glycemic management. Here we have the red labels and big pen, and this delivers either 0.25 mg or 0.5 mg. The recommendation for this medication is to use 0.25 mg for 4 weeks. Assess the patient's glycemic control, and if needed, increase to 0.5 mg after 4 weeks. Again, this pen delivers either 0.25 mg or 0.5 mg only. This blue-green–label Ozempic [semaglutide] delivers 1-mg dosing, so when your patient turns this one all the way to the end, the only number they will see will be 1. If your patient does not have optimal glycemic control with the lower doses, a 1-mg pen can be prescribed and the patient can continue on that, optimizing their glucose, or you can increase to a 2-mg pen [yellow label], which delivers only 2 mg. This is a single-use cartridge for Trulicity [dulaglutide]. The various doses of Trulicity are 0.75 mg, 1.5 mg, 3 mg, and 4.5 mg. This pen will deliver only the dose that's prescribed, and you can titrate up to optimize glycemic control for your patient. The higher the dose, the better the improvement in glucose and hemoglobin A1c. This is the pen for Mounjaro, which is tirzepatide. At the time of this recording, this medication is intended for type 2 diabetes management. It's a single-use cartridge, and the different doses vary from 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, to the highest dose, 15 mg. Again, this should be titrated to optimize glycemic control for your patient, and you can increase or decrease the dose based on the patient's tolerance. https://www.medscape.com/viewarticle/995911?src=soc_yt

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We say it on repeat but...GLP-1s aren't a magic pill. For sustainable weight loss, they work best when paired with healthy lifestyle changes. Here are 5 nutrition tips to proritize (that AREN'T restrictive or fad dieting) to support your weight loss journey: 🥗 1. Prioritize Protein – Keeps you full longer and supports muscle retention. Think eggs, chicken, tofu, and Greek yogurt. 🥑 2. Add Healthy Fats – Avocados, nuts, and olive oil help curb cravings and stabilize blood sugar. 🍞 3. Eat More Fiber – Whole grains, veggies, and beans keep digestion happy and prevent overeating. 🍽️ 4. Use the 80/20 Rule – Focus on whole, nutrient-dense foods 80% of the time while allowing room for treats. 🧃 5. Watch Liquid Calories – Sugary drinks add up fast. Stick to water, tea, or black coffee. Which one are you trying first? 👇 Website: https://joinweightcare.com/ Connect with us on socials! Instagram: https://www.instagram.com/weightcare_/ TikTok: https://www.tiktok.com/@weightcare Facebook: https://www.facebook.com/joinweightcare More about WeightCare We get it. Every journey is different. That's why we tailor our approach to your individual needs and goals. Transform your approach to weight loss: We offer accessible telemedicine, affordable science-backed treatments, and unwavering support to empower you to finally reach your health goals. We're not just another fad. We're grounded in science and backed by results. Join the tens of thousands of people already a part of WeightCare and begin your unique journey, we're with you every step of the way! Your trusted partner for a healthier, happier you.

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