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Dr. Riccardo De Giorgi is a Clinical Lecturer at the University of Oxford’s Department of Psychiatry and a senior psychiatric trainee with Oxford Health NHS Foundation Trust. Dr. De Giorgi is deeply engaged in clinical practice and academic research, focusing on treatment-resistant mood disorders. His work explores the role of immunological and metabolic factors in mental illness and the potential for repurposing existing medications, such as statins and GLP1 receptor agonists, to treat patients who don't respond to conventional therapies. Overall, Dr. Riccardo is a passionate educator in the field of psychiatry who is always looking at these disorders from an embodied perspective where the mind is not separate from the body. Note: When discussing ways in which compounds may enter the brain, I used the term "circumventricular brain regions" when the most appropriate way to describe it is through "circumventricular organs (CVOs). This might be too pedantic, but in Science, terminology is very important. Dr. Riccardo's work and papers discussed: GLP-1 Paper: http://doi.org/10.1038/s44220-025-00390-x Statin Paper: DOI: 10.1016/j.jad.2022.05.113 Creatine Paper: http://doi.org/10.1016/j.euroneuro.2024.10.004 Follow Dr.Riccardo's work: https://x.com/rdegiorgi https://orcid.org/0000-0001-5984-8696 Chapters: 0:00 Intro 2:14 Dr.Riccardo's research 4:07 Treatment Resistance in Psychiatry 8:07 Anhedonia and Depression 9:16 Side effects of psychiatric medications 13:43 Ketogenic diet and metabolic interventions 18:20 Do we need to target the brain to heal it? 22:45 Blood-Brain barrier 25:29 GLP-1 RAs and Anhedonia 29:35 Statins & Depression 33:24 Creatine Monohydrate 35:25 Medication and Increased Suicidality 41:06 Stigma and Perceived Uniqueness of Psychiatry 46:03 Biggest Challenges in Psychiatry 49:48 Problems in Science 51:57 Science Denial 52:50 Tips for those struggling #glp1medication #mentalhealth #metabolichealth #ozempic #psychiatry #psychology
Users Online Open Up About Using Ozempic And Other Weight Loss Drugs
“When hitting your goal becomes a risk to your immunity 🚨—strict dieting could lower your white blood cell count and weaken your defenses.”** 🔍 Key insights: * Sustaining a **25 % calorie reduction** for 2 years led to lower WBC and lymphocyte counts—though infection rates didn’t rise, inflammation markers dropped too * **Yo-yo dieting** (frequent weight loss and regain) may impair natural killer cell function long-term * In athletes, very **low-fat diets (15 %)** decreased WBC proliferation compared to moderate-fat diets (30 %) * **Low energy availability** (e.g. underfeeding for intense exercise) reduced leukocyte mobilization and increased markers of immune stress ✅ Bottom line: * Moderate calorie control is fine—but **extreme calorie cuts**, **yo-yo dieting**, or **very low-fat plans** can lower WBC levels and potentially reduce immune function. * If strictly dieting, regularly check blood counts, include healthy fats, and avoid frequent weight cycling. **#StrictDietRisks #ImmuneHealth #WBC #CalorieRestriction #YoYoDieting #FatIsNotTheEnemy #HealthyEating #BodyAndImmunity** **“మీ లక్ష్యాన్ని చేరుకోవడానికి ఇచ్చే నియమాలు… మళ్ళీ మీ రక్షణ వ్యవస్థకు ప్రమాదం 🚨—కఠిన ఆహార నియంత్రణ వల్ల మీ WBCలు తగ్గి, రోగనిరోధక శక్తి తగ్గే అవకాశం ఉంది.”** 🔍 ముఖ్యాంశాలు: * **25 % కాలరీ తగ్గింపు** 2 సంవత్సరాలు కొనసాగించగా, WBC & లింఫొసైట్స్ సంఖ్య తగ్గాయి, కానీ సంక్రమణలు పెరగలేదు – ఇన్ఫ్లమేషన్ కూడా తక్కువైంది ([pmc.ncbi.nlm.nih.gov][1]). * **యో‑యో డైట్** (వెయిట్ కోల్పోయి తిరిగి పెరిగే) వల్ల, నేచురల్ కిల్లర్ సెల్స్ పనితీరు తొడగినట్లు అధ్యయనం చూపింది . * కఠినమైన **తెక్కువ‑కొద్దిగా కొవ్వు లోప diet (15 %)** వలన WBC వృద్ధి తగ్గినట్లు athetaletes లో కనబడింది .
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While many hours of gruelling cardio, strict dieting and practically moving to the gym are still the PRIMARY methods to losing weight, there are little things we totally ignore – our habits! Change your habits, change your life! Because it's always the little things, that make a huge difference! Love and Higher Quality Habits, Faarah D. (Nutrition and Wellness Editor, Glamrs) For more videos, log on to http://www.glamrs.com
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With the rise of obesity rates worldwide, there has been an increased interest in medications that can aid in weight loss. Two drugs that have gained attention for their potential in promoting weight loss are semaglutide and tirzepatide. Both drugs belong to a class of medications known as GLP-1 receptor agonists, which work by mimicking the effects of a hormone called glucagon-like peptide-1 (GLP-1) that regulates blood sugar levels and appetite.
Comparing Effectiveness of Semaglutide and Tirzepatide
Semaglutide and tirzepatide have both shown promising results in clinical trials for weight loss, but they have some key differences in terms of their effectiveness and side effects. In this article, we will compare the two drugs and discuss their pros and cons to help you make an informed decision about which medication may be right for you.
Mechanism of Action
Semaglutide works by stimulating the release of insulin, reducing glucagon secretion, slowing gastric emptying, and suppressing appetite. This multifaceted approach makes it a potent weight loss medication. On the other hand, tirzepatide is a dual GIP and GLP-1 receptor agonist, meaning it targets two different pathways to regulate blood sugar levels and appetite. This dual mechanism of action could potentially make tirzepatide more effective for weight loss than semaglutide.
Clinical Efficacy
In clinical trials, both semaglutide and tirzepatide have been shown to help patients lose significant amounts of weight. Semaglutide has been studied in the STEP trials, which included participants with obesity or overweight who also had other health conditions such as type 2 diabetes. The results showed that semaglutide led to an average weight loss of around 15-17% of initial body weight. Tirzepatide has also shown promising results in clinical trials, with some studies reporting weight loss of up to 20% of initial body weight.
Side Effects
Both semaglutide and tirzepatide can cause side effects such as nausea, vomiting, diarrhea, and constipation. However, tirzepatide may have a higher risk of gastrointestinal side effects compared to semaglutide. Additionally, tirzepatide may be associated with an increased risk of hypoglycemia (low blood sugar levels) compared to semaglutide. It is important to discuss the potential side effects of each medication with your healthcare provider before starting treatment.
Cost and Accessibility
Another important factor to consider when choosing between semaglutide and tirzepatide is the cost and accessibility of the medications. Semaglutide is currently available as an injectable medication that is typically taken once a week. Tirzepatide, on the other hand, is still in development and has not yet been approved for use. The cost of these medications may vary depending on your insurance coverage and location, so it is important to consider these factors when making a decision.
Overall, both semaglutide and tirzepatide have shown promise as effective weight loss medications for individuals with obesity or overweight. It is important to consult with your healthcare provider to determine which medication may be right for you based on your individual needs and preferences. Remember that weight loss medications should be used in conjunction with a healthy diet and exercise regimen for the best results.
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Are you looking for a natural and effective way to support your weight loss goals? Look no further! Gold Coast Keto Gummies are now available at Chemist Warehouse, offering a convenient and tasty way to incorporate the benefits of keto into your daily routine. These gummies are formulated with powerful ingredients that can help you reach your fitness goals faster and more efficiently. In this article, we will take a closer look at Gold Coast Keto Gummies and how they can help you on your weight loss journey.
What are Gold Coast Keto Gummies?
Gold Coast Keto Gummies are a revolutionary supplement that combines the power of keto with the convenience of a gummy. These gummies are made with natural ingredients that are known to support the body’s fat-burning processes, making it easier for you to reach your weight loss goals. With Gold Coast Keto Gummies, you can enjoy the benefits of keto without having to follow a strict diet or deal with the unpleasant side effects of traditional keto supplements.
These gummies are designed to be easy to incorporate into your daily routine. Simply take the recommended dose each day, and let the powerful ingredients in Gold Coast Keto Gummies go to work for you. Whether you are looking to lose weight, increase your energy levels, or improve your overall health, these gummies can help you achieve your goals.
How do Gold Coat Keto Gummies work?
Gold Coast Keto Gummies work by supporting the body’s natural ketosis process. Ketosis is a state in which the body burns fat for fuel instead of carbohydrates, leading to rapid weight loss and increased energy levels. The ingredients in Gold Coast Keto Gummies are designed to help the body enter and maintain ketosis more easily, making it easier for you to burn fat and reach your fitness goals.
One of the key ingredients in Gold Coast Keto Gummies is exogenous ketones. These ketones are designed to help the body enter ketosis faster and stay in ketosis longer, leading to more significant weight loss results. By taking Gold Coast Keto Gummies regularly, you can support your body’s fat-burning processes and achieve your weight loss goals more quickly and efficiently.
Benefits of Gold Coast Keto Gummies
There are many benefits to incorporating Gold Coast Keto Gummies into your daily routine. Some of the most notable benefits include:
1. Weight loss – Gold Coast Keto Gummies can help you burn fat more efficiently, leading to faster weight loss results.
2. Increased energy – By burning fat for fuel, Gold Coast Keto Gummies can help you experience a steady and sustained energy boost throughout the day.
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3. Improved focus – Ketones are known to support cognitive function, helping you stay focused and alert throughout the day.
Are there any side effects?
As with any supplement, it is essential to consult with a healthcare professional before taking Gold Coast Keto Gummies, especially if you have any underlying health conditions or are taking medications. While Gold Coast Keto Gummies are generally considered safe for most people, some individuals may experience mild side effects such as digestive issues or headaches. If you experience any adverse reactions, discontinue use and consult with your doctor.
Overall, Gold Coast Keto Gummies are a safe and effective way to support your weight loss goals and improve your overall health. With their convenient gummy form and powerful ingredients, these gummies can help you reach your fitness goals faster and more efficiently. So why wait? Pick up a bottle of Gold Coast Keto Gummies at Chemist Warehouse today and start your weight loss journey!
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90 Days To Lose Fat: Day 6 (Day-6) 90 Days Fat Loss Journey #gym gym freak gym workout home workout Welcome back to my 90-day fat loss challenge! We're on day 6 and I'm excited to share my progress with you. In this video, I'll be taking you through my home workout routine, which has been a game-changer for my weight loss motivation. As a gym freak, I've always believed that a combination of a healthy diet and regular exercise is key to achieving a fitness transformation. My goal is to lose belly fat and reveal a leaner, more toned physique by the end of these 90 days. If you're struggling to find motivation to lose weight fast, I hope my journey inspires you to take control of your own fitness transformation. Remember, it's not just about the number on the scale, but about feeling confident and motivated to transform your body. Let's do this! Fat loss, Challenge, Gym freak, Home workout, weight loss, gym motivation, weight loss motivation, fat burning, home gym, motivational speech, workout motivation, body transformation, lose belly fat, fitness transformation, fitness journey, lose weight fast, burn belly fat, fat loss tips, workout challenge, belly fat loss, home fitness, gym lifestyle, motivation boost, transform your body, home workout, cardio workout, 30 minute workout, fat loss, gym routine
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