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Welcome to Episode 3 of our Type 2 Diabetes series! In this detailed, evidence-based episode, Dr. MO Elmisiry (MBBCh) explores the cornerstones of type 2 diabetes management. focusing on the pharmacologic roles of SGLT2 inhibitors, GLP-1 receptor agonists, and DPP-4 inhibitors. 🔍 What you’ll learn: Overview of the ADA/EASD glycemic management algorithm (2024) When to start monotherapy, dual, or triple therapy based on A1C levels Pharmacology, mechanisms of action, and clinical pearls of: 🔵 SGLT2i (e.g., empagliflozin, dapagliflozin): CV, renal benefits & glycemic control 🟢 GLP-1 RAs (e.g., semaglutide, liraglutide): weight loss & ASCVD benefit 🟣 DPP-4i (e.g., sitagliptin, linagliptin): safe in elderly & renal patients How to individualize therapy based on comorbidities (ASCVD, HF, CKD) 00:00 Introduction 01:10 High yield notes for Management 08:42 Prediabetics management 2025 10:28 How to choose second line 12:38 Insulin therapy steps 14:11 Old treatment according to A1c level 14:54 SGLT2i Pharmacology 18:52 Best For? 20:30 Dosing & Trade names 25:20 How GLP-1 RA and DPP-4i work? 29:49 GLP-1 RA pharmacology 32:23 Best For? 33:45 Dosing and Trade names 38:06 DPP-4i pharmacology 39:32 Best For? 40:13 Dosing and Trade names Create a PowerPoint like this: https://gamma.app/signup?r=fhjwoprdsktd11u Join our Facebook group: https://www.facebook.com/ReadyResident Support me via Instapy: https://ipn.eg/S/elmisiry/instapay/2xuNe7 📚 Key Guidelines Referenced: BMJ Best Practice (2025) ADA 2025, WHO, and leading endocrinology resources 📢 Like, share, and subscribe for more evidence-based emergency medicine and surgical tutorials. 🔔 Turn on notifications so you don’t miss our next case-based simulation!
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Always trying to find safe fast food places that offer low calorie options! Weight loss doesn’t mean you can never eat fast food again. It just means you have to find things to order that work for your plan. Sonic is one of those places for me!
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