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Dr Tamaan K. Osbourne-Roberts reviews the list of patients who probably should not be taking GLP-1 receptor agonists. https://www.medscape.com/viewarticle/glp-1-ras-when-not-prescribe-2024a1000nd8?src=soc_yt -- TRANSCRIPT -- Hi. I'm Tamaan K. Osbourne-Roberts, family medicine physician and lifestyle medicine physician, here to discuss GLP-1 receptor agonist (RA) contraindications — the skinny on when not to prescribe. It can be hard not to think of GLP-1 RAs like Ozempic and Mounjaro as silver bullets, long-awaited miracle drugs that we should probably be putting in the water. And it's true they have the potential to help a lot of people. However, there are definitely groups of patients who should not take these drugs or should take them with caution. They include the following: Patients with a family history of certain cancers. Given that GLP-1 RAs can increase the risk for thyroid cancer, patients with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia type 2 should not take these drugs. Gut motility issues. Since one of the primary mechanisms of action for these drugs is to slow down the gut, patients with gastroparesis — diabetic or otherwise — or other gut motility issues should avoid these drugs. Patients with inflammatory bowel disease also should not use GLP-1 RAs. Pancreatitis. These medications can increase the risk for serious pancreatitis on their own, so use in patients who have had pancreatitis already is not recommended. Renal impairment. An eGFR [estimated glomerular filtrationrate] below threshold, typically around 30 mL/min/1.73 m2, excludes GLP-1 RAs for some patients. Be certain to check the threshold for individual medications before prescribing. And finally, pregnancy. These drugs generally should not be used in pregnancy, and people of childbearing age with the ability to become pregnant should use contraception while taking these medications. GLP-1 RAs are great medications and have the potential to revolutionize obesity medicine, but like all drugs, it's important to use them safely. Knowing when not to prescribe them is an important step in ensuring patient safety and will help ensure they are available for those who need them. Transcript in its entirety can be found by clicking here: https://www.medscape.com/viewarticle/glp-1-ras-when-not-prescribe-2024a1000nd8?src=soc_yt
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Protein ist ein wichtiger Nährstoff, der bei einer Diät eine entscheidende Rolle spielt. Es hilft nicht nur beim Aufbau und Erhalt von Muskelmasse, sondern kann auch den Stoffwechsel ankurbeln und das Sättigungsgefühl erhöhen. Bei der Auswahl von Proteinquellen für die Diät ist es entscheidend, auf die Qualität und Vielfalt der Proteine zu achten. In diesem Artikel werden optimale Proteinquellen für die Diät vorgestellt, die Ihnen dabei helfen, Ihre Gesundheitsziele zu erreichen.
Pflanzliche Proteinquellen
Pflanzliche Proteinquellen sind reich an Ballaststoffen und enthalten in der Regel weniger gesättigte Fettsäuren als tierische Proteine. Zu den besten pflanzlichen Proteinquellen gehören Hülsenfrüchte wie Bohnen, Linsen und Kichererbsen. Diese sind nicht nur reich an Protein, sondern auch an wichtigen Vitaminen und Mineralstoffen wie Eisen und Magnesium. Nüsse und Samen wie Mandeln, Chiasamen und Leinsamen sind ebenfalls hervorragende Proteinquellen, die sich ideal für eine ausgewogene und gesunde Ernährung eignen.
Soya-Produkte wie Tofu und Tempeh sind ebenfalls reich an Protein und eignen sich gut für eine vegetarische oder vegane Ernährung. Sie sind vielseitig in der Küche einsetzbar und lassen sich zu verschiedenen Gerichten verarbeiten. Quinoa ist ein weiteres pflanzliches Protein, das alle neun essentiellen Aminosäuren enthält, die der Körper nicht selbst herstellen kann. Es ist ein glutenfreies Getreide und eine gute Alternative zu Vollkornprodukten.
Tierische Proteinquellen
Tierische Proteinquellen wie Fleisch, Fisch und Geflügel sind reich an hochwertigem Protein und wichtigen Nährstoffen wie Vitamin B12 und Eisen. Mageres Fleisch wie Huhn und Truthahn ist eine gute Proteinquelle mit wenig Fett, während Fisch wie Lachs, Thunfisch und Makrele reich an Omega-3-Fettsäuren ist, die entzündungshemmende Eigenschaften haben. Eier sind eine erschwingliche Proteinquelle, die alle neun essentiellen Aminosäuren enthält und sich vielseitig in der Küche verwenden lässt.
Milchprodukte wie Joghurt, Käse und Milch sind ebenfalls gute Proteinquellen, die reich an Kalzium und Vitamin D sind. Griechischer Joghurt ist besonders proteinreich und eignet sich gut als Snack oder Zutat in Smoothies und Desserts. Käse liefert neben Protein auch gesunde Fette und ist eine leckere Ergänzung zu vielen Gerichten. Milch ist nicht nur reich an Protein, sondern auch an Kalzium, das wichtig für starke Knochen und Zähne ist.
Proteinreiche Snacks und Nahrungsergänzungsmittel
Proteinreiche Snacks wie Proteinriegel, Nüsse und Samenmischungen sind eine praktische Möglichkeit, den Proteinbedarf zu decken und Heißhungerattacken zu vermeiden. Proteinriegel sind in verschiedenen Geschmacksrichtungen erhältlich und eignen sich gut als Zwischenmahlzeit oder nach dem Training. Nüsse und Samenmischungen sind reich an Protein, Ballaststoffen und gesunden Fetten und sorgen für langanhaltende Energie.
Proteinshakes und -pulver sind eine bequeme Möglichkeit, den Proteinbedarf zu decken, besonders für Menschen, die einen aktiven Lebensstil haben oder Schwierigkeiten haben, ausreichend Protein über die normale Ernährung aufzunehmen. Sie sind in verschiedenen Geschmacksrichtungen erhältlich und können einfach mit Wasser oder Milch gemischt werden. Proteinriegel und -pulver sollten jedoch als Ergänzung zur normalen Ernährung betrachtet werden und nicht als Ersatz für eine ausgewogene Mahlzeit.
Proteinquellen in der Diät richtig kombinieren
Um alle essentiellen Aminosäuren zu erhalten und die optimale Proteinversorgung sicherzustellen, ist es wichtig, Proteinquellen in der Diät richtig zu kombinieren. Eine ausgewogene Ernährung mit einer Vielzahl von Proteinquellen aus tierischen und pflanzlichen Quellen kann dabei helfen, alle notwendigen Nährstoffe und Aminosäuren zu erhalten. Zum Beispiel können Hülsenfrüchte mit Getreide wie Reis oder Brot kombiniert werden, um eine vollständige Proteinquelle zu schaffen.
Es ist auch wichtig, auf die Qualität der Proteinquellen zu achten und verarbeitete Lebensmittel mit hohem Zucker- und Fettgehalt zu vermeiden. Frische, natürliche Proteinquellen wie mageres Fleisch, Fisch, Eier, Hülsenfrüchte, Nüsse und Samen sind die besten Optionen für eine gesunde und ausgewogene Diät. Eine ausreichende Flüssigkeitszufuhr ist ebenfalls wichtig, um die Verdauung und den Stoffwechsel zu unterstützen und die Aufnahme von Protein zu optimieren.
Abschließend ist es wichtig, dass Sie auf Ihre individuellen Bedürfnisse und Ziele achten, wenn es darum geht, optimale Proteinquellen für Ihre Diät auszuwählen. Eine ausgewogene Ernährung mit einer Vielzahl von pflanzlichen und tierischen Proteinquellen kann dazu beitragen, Ihre Gesundheit und Fitnessziele zu erreichen. Denken Sie daran, dass Protein nicht nur wichtig für den Muskelaufbau ist, sondern auch für den allgemeinen Stoffwechsel und die Sättigung.
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