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In this evidence-based video, we break down the pharmacology of GLP-1 receptor agonists (GLP-1 RAs)—a rapidly expanding class of antidiabetic and weight-loss medications. Designed for physicians, pharmacists, nurse practitioners, and other healthcare professionals, this video covers: ✅ Mechanism of action ✅ Pharmacokinetics and pharmacodynamics ✅ Differences between short-acting vs long-acting agents ✅ Clinical indications (T2DM, obesity) ✅ Cardiovascular and renal benefits ✅ Common side effects and safety profile ✅ Overview of agents like liraglutide, semaglutide, dulaglutide, and more 00:00 Intro & Incretins 01:28 Mechanism of action 05:23 GLP-1 RA Members 06:28 Side Effects 06:53 Benefits 08:02 Contraindications 08:30 First line for? 10:03 Dosing and Trade names 14:45 Growing Evidence Create a PowerPoint like this: https://gamma.app/signup?r=fhjwoprdsktd11u Join our Facebook group: https://www.facebook.com/ReadyResident Support me via Instapy: https://ipn.eg/S/elmisiry/instapay/2xuNe7 📚 Key Guidelines Referenced: BMJ Best Practice (2025) ADA 2025, WHO, and leading endocrinology resources 📚 Evidence-based and updated with the latest guideline recommendations (ADA, ESC, KDIGO). 📢 Like, share, and subscribe for more evidence-based emergency medicine and surgical tutorials. 🔔 Turn on notifications so you don’t miss our next case-based simulation!

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