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Discussing GLP-1 Agonists and Weight Loss Journeys with James Newburrie In this episode of The Downsized, hosts Christopher and Laraine Durham share their experiences with GLP-1 agonists Zepbound, Mounjaro, Wegovy, Ozempic, semaglutide, tirzepatide, and its substantial impact on their weight loss journey. They welcome James Newburrie, a computer nerd from Melbourne, Australia, who discusses his lifetime struggle with weight, the toxic diet culture of the 1980s, and his transformative experience with GLP-1 medications. James highlights the significant lifestyle and dietary changes he undertook and the profound mental shifts facilitated by these medications. This episode dives deep into personal hardships, the flawed diet industry, and the scientific approach to addressing metabolic disorders. 🌟 DOWNSIZED GLP-1 COMPANION PRODUCT STORE: https://thedownsized.org/downsized-st... DOWNSIZED WEBSITE: https://thedownsized.org/ Start your weight loss journey today! We use Mochi Health: https://joinmochi.com/. Use Laraine’s code for $40 off: QIYGO8. 00:00 Introduction to The Downsized 00:40 Meet James Newburrie 01:17 James' Early Struggles with Weight 02:25 The Impact of 1980s Diet Culture 03:38 The Blame Game: Food Industry and Beyond 06:59 James' Turning Point in 2019 08:07 Pandemic Challenges and Weight Gain 13:19 Discovering GLP-1 Medications 17:29 Life-Changing Effects of Trizepatide 21:52 Reevaluating Life and Free Will 22:59 Shared Struggles and Fitness Goals 24:05 Diet Fatigue and Relationship with Food 24:54 Concerns About Medication Availability 25:30 Cost and Logistics of Medication 26:32 Side Effects and Adjustments 28:41 Diet and Nutrition Details 33:00 Toxic Diet Culture Discussion 40:17 Reflections and Future Plans 41:43 Closing Remarks and Gratitude

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*Unlock the Power of GLP-1 Agonists for Longevity and Health!* In this must-listen episode of The Longevity Show, Dr. Hillary Lin reveals the groundbreaking benefits of GLP-1 receptor agonists—medications that do far more than just aid with diabetes or weight loss. Discover how GLP-1 agonists are becoming the go-to solution for heart health, brain support, inflammation reduction, and even life extension! Explore the latest science-backed insights into their transformative effects, covering: • How GLP-1 agonists work to promote sustainable weight loss and balanced blood sugar • The powerful role they play in reducing inflammation and supporting cardiovascular health • Neuroprotective effects that could help guard against cognitive decline Dr. Hillary Lin also shares practical advice on how to safely incorporate these medications into a longevity-focused health routine. In this episode, you’ll learn to: ✓ Harness GLP-1 agonists to enhance metabolic health and weight management ✓ Support heart and kidney health with this innovative therapy ✓ Unlock their potential for neuroprotection and extended vitality Don’t miss the opportunity to level up your health journey and add this powerful tool to your longevity arsenal! Tune in now and start taking charge of your health, one breakthrough at a time. *Chapters* 01:11 GLP-1 Agonists: Beyond Diabetes 08:06 Anti-Inflammatory Effects of GLP-1 Agonists 11:02 Cardiovascular Health and GLP-1 Agonists 22:10 GLP-1 Agonists: Unlocking Brain Health 26:22 Transforming Gut Health for Holistic Wellbeing 32:58 Kidney Health and GLP-1 Agonists 37:58 The Risks and Adverse Effects of GLP-1 Agonists 45:39 Summary of GLP-1 Agonists Benefits ✨ Get 5 Easy Longevity Tips & Dr. Hillary Lin’s Weekly Newsletter for Free: https://www.hillarylinmd.com/subscribe *About the Show:* The Longevity Show with Dr. Hillary Lin takes complex medical research and distills it into practical, easy-to-understand advice for living a longer, healthier life. Covering everything from preventative medicine and metabolic health to the latest breakthroughs in nutrition, exercise, and mental wellness, Dr. Lin gives you the tools you need to thrive. ‍ *Connect with Dr. Hillary Lin:* Instagram: https://www.instagram.com/hillarylinmd Facebook: https://www.facebook.com/hillarylinmd X: https://x.com/hillarylinmd TikTok: https://www.tiktok.com/@hillarylinmd Got questions? Ask Dr. Hillary Lin directly on NoomVibe: https://noomvibe.app/hillarylinmd/ask *Disclaimer:* This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

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Source: https://www.podbean.com/eau/pb-qqah5-17fe68b The Next Gen Pharmacy Conference, ATRIUMX February 27 – March 1, 2025 The conference that puts you in control— you create the content. Thank you Independent Pharmacy Cooperative (IPC) for sponsoring this episode of TWIRx! Check out the iCare+ digital health platform: https://myicareplus.com/ 2-Part Special: FIRST -- Special guests: Atrium24 founder, Dr. Nicolette Mathey PharmD, ATRIUMX organizers Kelley Babcock, and Jen Diehl, and Pharmacy Busienss Consultant and owner Donnie Jordan Vice President Pharmacy Strategy at Health Growth Pharmacy Solutions. SIGN UP HERE: https://atrium24.io/atriumx-conference-attendees/ NEXT -- on the second half of TWIRx, we talk with Dr. Julie Schulz, MD, MPH and Dr. Michael Dovidio, PharmD from Avalon Health talk about the challenges of 'quick fix' treatments and weight management plans with the inclusion of GLP-1s. From the article titled: "How to Maximize the Value of GLP-1 Drugs While Improving Health Equity" --Julie and Mike talk about the real world needs of people who want to lose weight, doing it the right way for long term benefit. Due to the continued high cost, only patients with greater financial resources or those with generous employer-sponsored drug benefits will be able to afford the medications for obesity. This can exacerbate health inequities, likely driving significantly higher costs for public and commercial health plans, intensified by the new financial strain from weight loss medications. Rather than denying coverage for GLP-1s for obesity, health plans could modify eligibility policies to require data from a standardized set of laboratory tests and other biometrics to identify patients in most need of GLP-1s and verify medical necessity. This approach would reduce inappropriate prescribing while ensuring that patients who are most likely to benefit from the drugs have access to them.

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