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Discover the top 5 weight loss drugs of April 2025, ranked from least to most effective based on clinical trial data! From Alli to the game-changing Zepbound, we cover brand names, company names, US availability, and weight loss claims. Trust our science-backed list—watch till the end for the #1 stunner! 💉 Study links below. Like, comment, and subscribe for more reliable health insights! Disclaimer: Consult a healthcare professional before starting any medication. Studies Supporting the Ranking: 1. Orlistat (Alli): Sjöström, L., et al. (1998). Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain. The Lancet. https://doi.org/10.1016/S0140-6736(98)02264-3 2. Contrave: Greenway, F. L., et al. (2010). Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I). The Lancet. https://doi.org/10.1016/S0140-6736(10)60888-4 3. Saxenda (Liraglutide): Pi-Sunyer, X., et al. (2015). A randomised, controlled trial of 3.0 mg of liraglutide in weight management. New England Journal of Medicine. https://doi.org/10.1056/NEJMoa1411892 4. Wegovy (Semaglutide): Wilding, J. P. H., et al. (2021). Once-weekly semaglutide in adults with overweight or obesity. New England Journal of Medicine. https://doi.org/10.1056/NEJMoa2032183 5. Zepbound (Tirzepatide): Jastreboff, A. M., et al. (2022). Tirzepatide once weekly for the treatment of obesity. New England Journal of Medicine. https://doi.org/10.1056/NEJMoa2206038 #WeightLoss #Health #Zepbound

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