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Welcome to Episode: 73 The ever-increasing issue of obesity and its related health complications brings with it the need for effective treatment. We are joined today by a board-certified vascular and interventional radiologist, Dr. Moises Roizental, to talk all things weight loss and obesity medication (specifically GLP-1 agonists). Dr. Roi explains the challenge of overcoming obesity and the role GLP-1 agonists play in alleviating the struggle. We learn about the multitude of benefits, obesity-related and otherwise, as well as the indications, contraindications, and side effects. Tune in to hear about the long-term benefits of investing in your health and how to get the best results from this life-changing medication! Links Mentioned in Today’s Episode: Dr. Moises Roizental on LinkedIn https://www.linkedin.com/in/drroizental/ Dr. Moises Roizental on Twitter https://twitter.com/drroizental Dr. Moises Roizental on Instagram https://www.instagram.com/drroi Email Dr. Moises Roizental [email protected] Hambre y Hormonas https://hambreyhormonas.com/ Hambre y Hormonas on Instagram https://www.instagram.com/hambreyhormonas/ Wegovy https://www.wegovy.com/ Ozempic https://www.ozempic.com/ Saxenda https://www.saxenda.com/ Mounjaro https://www.mounjaro.com/ Click HERE to save on BiOptimizers Magnesium https://magbreakthrough.com/andres Andrés Preschel https://andrespreschel.com/ Know Your Physio Podcast https://andrespreschel.com/podcast/

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When it comes to managing weight and improving overall health, many individuals turn to medications to help aid in their journey. Two common medications that are frequently prescribed for weight loss are Metformin and Semaglutide. Both drugs have shown promising results in helping individuals shed excess pounds, but many people are left wondering which is more effective. In this article, we will delve into the differences between Metformin and Semaglutide and explore which one may be more beneficial for weight loss.

Metformin: A Commonly Prescribed Medication for Weight Loss

Metformin is a commonly prescribed medication for individuals with type 2 diabetes, as it helps to lower blood sugar levels by improving insulin sensitivity. In addition to its glucose-lowering effects, Metformin has also been shown to aid in weight loss in some individuals. It is believed that Metformin works by reducing appetite and decreasing the absorption of carbohydrates in the gut, leading to a decrease in overall caloric intake.

One study found that individuals who took Metformin for weight loss experienced an average weight loss of 2-3 kg over a 6-month period. While this may not seem like a significant amount of weight loss, even small changes in weight can have a positive impact on overall health, particularly for individuals who are overweight or obese. Additionally, Metformin is generally well-tolerated and has few side effects, making it a popular choice for individuals looking to lose weight.

However, it is important to note that Metformin is not a miracle drug, and results may vary from person to person. Some individuals may not experience any weight loss while taking Metformin, while others may experience more significant results. It is also important to combine Metformin with a healthy diet and regular exercise for optimal weight loss results.

Semaglutide: A Newer Option for Weight Loss

Semaglutide is a newer medication that has shown promising results in helping individuals lose weight. Originally developed as a treatment for type 2 diabetes, Semaglutide was found to have significant weight loss benefits in clinical trials. It is believed that Semaglutide works by decreasing appetite and increasing feelings of fullness, leading to a decrease in food intake and subsequent weight loss.

In a clinical trial involving over 2,000 participants, those who took Semaglutide for weight loss experienced an average weight loss of around 15% of their body weight over a 68-week period. This is a significant amount of weight loss compared to other weight loss medications on the market. Additionally, Semaglutide has been shown to have a positive impact on other health markers, such as blood pressure and cholesterol levels.

Like Metformin, Semaglutide is generally well-tolerated, with some individuals experiencing mild side effects such as nausea or diarrhea. However, Semaglutide is not suitable for everyone, particularly those with a history of pancreatitis or thyroid cancer. It is important to consult with a healthcare provider before starting Semaglutide for weight loss.

Comparing Metformin and Semaglutide for Weight Loss

When comparing Metformin and Semaglutide for weight loss, it is clear that Semaglutide may be more effective in helping individuals shed excess pounds. While Metformin can lead to modest weight loss in some individuals, Semaglutide has been shown to produce more significant results, with some participants losing up to 15% of their body weight.

However, it is important to consider the individual needs and preferences of each person when choosing between Metformin and Semaglutide for weight loss. Metformin may be a suitable option for individuals with type 2 diabetes who are looking to lose weight or improve insulin sensitivity, while Semaglutide may be a better choice for those who are not seeing results with other weight loss medications.

Ultimately, the decision to use Metformin or Semaglutide for weight loss should be made in consultation with a healthcare provider. They can help determine which medication is best suited to an individual’s unique needs and health goals. Regardless of which medication is chosen, it is important to combine it with a healthy diet and regular exercise for long-term weight loss success.

Overall, both Metformin and Semaglutide have their own benefits and drawbacks when it comes to weight loss. By understanding the differences between these medications and working with a healthcare provider, individuals can make an informed decision about which option may be more effective for their weight loss journey.

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