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While looking over the research on the effect of GLP-1 receptor agonists on alcohol consumption, I stumbled across a recent and _really_ interesting paper on how that class of drugs affects sensation. It's "Glp-1 Receptor Agonists Significantly Impair Taste Function" by Rafa Khan and Richard L. Doty in _Physiology & Behavior_ Vol. 291 (published version at https://www.sciencedirect.com/science/article/abs/pii/S003193842400341X and white paper version at https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4953499 ). Don't necessarily take that title on its face, as the details are super important and incredibly interesting and maybe not as dire as you'd think. And, well, I felt like it would be a good use of my platform to discuss all of this. So that's what we're doing today, talking about this hugely consequential new class of drugs - Wegovy/Ozempic (semaglutide), Mounjaro (tirzepatide, although that's also a GIP), and whatever else is going to be out there - with an eye towards spirits nerdery. First I broadly discuss the history and basic mechanisms of these drugs, with a brief detour into side effects and what I would consider to be "best practices" in using them for weight loss purposes. (N.b., I don't get into treatment for type 2 diabetes and that's another set of concerns, also I am not a doctor and please consult a medical professional for all this etc..) And then I discuss the paper above. And... well, it's complicated. Based on their results I think the main takeaway is that while GLP-1 agonists seem to have very good odds of degrading your sense of taste, there's also pretty good odds that you won't actually notice. 🤷 Extra special thanks to my Different Spirits on Patreon (https://www.patreon.com/differentspirits), who got this video first - Eric Amig Anthony Darcy Bean Jamie Brown Kingsbury bushcraft William Christopher Clematis Rob D Liam Davitt Joe Devine Samuel Dose Stephen Eckert eon Ingmar nine Steve Frazee Ian Gendler Solomon Grundy John Halliday Alex Hurd Trevor Jarrait Jonathan Lestingi Kyaru Ariel Mserious Craig Nielsen Jason Newquist No Thanks Chris Rhodes Randy Rice RumSquirrel Gordon W Zach W

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Does The New Weight Loss Drug Wegovy Lead To Weight Loss

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Quantum Keto Gummies have taken the health and wellness world by storm, as more and more people are looking for effective ways to support their weight loss goals. These gummies are specially formulated to provide a convenient and tasty way to supplement the popular keto diet. If you’re considering trying Quantum Keto Gummies, you may be wondering about their benefits, reviews, and how to choose the best option on Amazon. In this article, we’ll explore the key features of Quantum Keto Gummies and help you make an informed decision about incorporating them into your daily routine.

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