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After the birth of her third child last August, Ciara posted to Instagram that she wanted to lose 48 lbs.*. Now about six months into her journey with WeightWatchers, the singer opened up to Oprah about how the weight loss is going ("I have about 18 lbs.* left"). The pair also talked about the prayer that brought Ciara's husband NFL quarterback Russell Wilson into her life, three things she's thankful for, and her message to all the fellow moms watching. The conversation was part of a Oprah's "Your Life in Focus: Be the Love You Need" event, presented by WW, which aired in front of a live, Zoom-based studio audience on February 13. Of her WeightWatchers journey thus far, Ciara says: "It's a lifestyle. It's about total wellness. It's about the big picture. That's a part of life: You've got to allow yourself to enjoy the process. Enjoy yourself. It's okay to have a little fun. You need to have a little fun. If we're so intense about everything we'll go crazy, especially during this pandemic and being a mom of three. It's like I've got to give grace. I've got to give grace in the process. And in the WW program, it's really easy." ►►To watch the full event, go to https://www.youtube.com/watch?v=2CkRnhaf764 ►►Still haven’t subscribed to WW on YouTube? https://www.youtube.com/user/weightwatchers?sub_confirmation=1 *People following the WeightWatchers program can expect to lose 1-2 lbs/week. #oprah #ciara #betheloveyouneed #ww

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HIIT workouts are highly recommended for burning calories and losing weight fast. This workout will work your core to tone your belly and get abs!! Today's workout can be done everyday for the next 15 days for faster results. Just remember to watch what you eat and stay away from grains and sugar. Also, motivation and discipline is the key. Without it, no amount of effort will help you. Good luck, have fun, and I'll see you here again tomorrow!❤️💪 **If you want to be notified when I upload a new video, make sure to subscribe to our channel. I upload new videos everyday from Sunday to Friday! TIMECODES: 00:00 Introduction 00:11 Slow Jumping Jacks 00:42 Rest 00:59 Slow Mountain Climber 01:31 Rest 01:48 Ski Jumps 02:20 Rest 02:37 Walk Downs 04:55 Rest 05:12 Split Jumps 05:38 Rest 05:55 Woodchoppers Left 06:54 Rest 07:11 Woodchoppers Right 08:10 Rest 08:32 Slow Jumping Jacks 09:03 Rest 09:20 Slow Mountain Climber 09:52 Rest 10:10 Ski Jumps 10:41 Rest 10:58 Walk Downs 13:16 Rest 13:33 Split Jumps 13:59 Rest 14:16 Woodchoppers Left 15:15 Rest 15:32 Woodchoppers Right 16:31 Rest 16:53 V Up 17:55 Rest 18:12 U Boat Crunch 18:58 Rest 19:15 T Plank 21:04 Rest 21:26 V Up 22:28 Rest 22:45 U Boat Crunch 23:31 Rest 23:48 T Plank

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(https://isappscience.org/wp-content/uploads/2025/07/Greiner-cover.png) This episode features Dr. Thomas Greiner PhD from the University of Gothenburg (Sweden), speaking about the various functions of GLP-1 in the gut, and the role of gut microbes in GLP-1 production, with ultimate effects on host health. He noted that GLP-1 is produced by enteroendocrine cells called L-cells, both in the small intestine and the colon. These cells respond to nutrients and microbially-produced short-chain fatty acids, but responses differ between the small intestine and colon, leading Dr. Greiner to investigate the different functions of GLP-1 at these two sites. Using germ-free mice and other models, Dr. Greiner has developed a hypothesis that the function of GLP-1 in the small intestine is to improve insulin secretion postprandially, whereas the functions of GLP-1 in the colon are to allow for increased energy intake (in a situation of energy deficiency), dampen inflammation, and protect local tissues. He and his colleagues are taking two different approaches in aiming to improve metabolic health in humans: finding inhibitors of bacterial enzymes to decrease production of a harmful molecule produced by bacteria; and a probiotic approach of administering butyrate-producing bacteria. With the latter approach, the sensitivity of the bacteria to oxygen is a problem to overcome, but their group has evolved a bacterial strain to tolerate some oxygen, with the idea of testing it as a probiotic. Episode abbreviations and links: • Paper exploring the role of the gut microbiota in GLP-1 signaling: GLP-1R signaling modulates colonic energy metabolism, goblet cell number and survival in the absence of gut microbiota (https://www.sciencedirect.com/science/article/pii/S2212877824000553?via%3Dihub) • Study on the functions of GLP-1 in the colon: Microbial Modulation of Energy Availability in the Colon Regulates Intestinal Transit (https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(13)00365-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS193131281300365X%3Fshowall%3Dtrue) • Bäckhed Lab Instagram account: @backhed_lab (https://www.instagram.com/backhed_lab?igsh=MWdpdmlndDAxOWFjag==) About Dr. Thomas Greiner PhD: Thomas Greiner is a medical scientist at the Wallenberg Laboratory, University of Gothenburg, with over 15 years of experience in functional genetics and metabolic research. His work focuses on the intricate interplay between gut microbiota, intestinal hormones such as GLP-1, and host metabolism. He has explored how microbial and hormonal signals influence energy balance, intestinal function, and the development of metabolic diseases. His research primarily uses molecular approaches in mouse models to investigate the role of microbial signals in metabolic disease and to uncover new functions of gut hormones in regulating intestinal physiology. Sign up (https://isappscience.org/for-scientists/news/isapp-newsletters/) for our monthly newsletter Follow us (https://isappscience.org/contact/)  on LinkedIn, Bluesky, X, Facebook, Instagram, Threads The post Unraveling the functions of GLP-1 in the gut, with Dr. Thomas Greiner PhD (https://isappscience.org/episode-65-unraveling-the-functions-of-glp-1-in-the-gut/) appeared first on International Scientific Association for Probiotics and Prebiotics (ISAPP) (https://isappscience.org) .

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