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"It's not that we have non-responders. It's that we have unrealistic expectations." - 00:20:38 A Personal Insight from Greece: Aligning Your Environment with Your Energy Dr. Novitsky begins by sharing a story from her trip to Greece, where the simplicity of her surroundings inspired her to declutter her home. This serves as a metaphor for aligning one's environment with their energy and current needs. Common Concerns About GLP-1 Agonists Dr. Novitsky discusses why people often struggle with GLP-1 agonists. Two main reasons stand out: confusion over how to balance medication with nutrition and exercise, often accompanied by shame, and the belief that they are "non-responders" to the medication. How a Nutrition Audit Can Help For those who feel they are non-responders, Dr. Novitsky introduces the concept of a nutrition audit. By tracking food intake without changes for a week, clients can gather data on calories, protein, carbs, fat, fiber, and added sugars. This helps uncover what might be hindering progress. The Importance of Caloric Deficits and BMR Dr. Novitsky explains that GLP-1 agonists don't guarantee weight loss. Weight loss still requires a caloric deficit, which means consuming fewer calories than one's basal metabolic rate (BMR). Many mistakenly believe they’re in a deficit when they’re not, leading to frustration. Leptin Resistance and Weight Loss Struggles The episode dives into leptin resistance, a condition that can make weight loss harder, even when someone is consuming fewer calories. Leptin plays a role in hunger and metabolism, and resistance to it may be a reason some struggle with weight loss. Patience and Realistic Expectations Dr. Novitsky stresses patience when using GLP-1 agonists, explaining that weight loss varies by individual. Inflammation, body composition, and initial body fat all play a role in determining how quickly one may lose weight. She advises setting realistic goals to avoid discouragement. Looking Ahead Dr. Novitsky wraps up by encouraging listeners to reflect on their own journey, asking them to consider if any of the factors discussed apply to their experience. She teases upcoming episodes that will provide further insights into GLP-1 agonists and weight loss strategies. Resources: The Muscles & Mindset Beginner Strength Training Program - 12 months for only $199! ⁠Enroll TODAY⁠. Nutrition Training Program for Healthcare Professionals is enrolling now! You can ⁠learn more HERE⁠. Dr. Ali's Advanced Strength Training program is now available for exercises at a higher level. See the details ⁠HERE⁠. Optimal GLP-1 Weight Loss Program - next program starts November, 2024. Learn more and join the waitlist ⁠HERE⁠. Transform® 9.0 enrollment is now open! Get started with your bonus content today. ⁠Learn more HERE⁠. Follow Dr. Ali Novitsky on ⁠TikTok⁠ | ⁠Facebook⁠ | ⁠Instagram⁠ | ⁠YouTube⁠ Subscribe to The Muscles and Mindset Podcast on ⁠Spotify⁠ | ⁠Apple Podcasts⁠ *Ali Novitsky MD, this podcast, and podcast write-up are NOT providing medical advice. We do not recommend you start any exercise program without first consulting with your doctor!* Timestamps 00:00:00 - Introduction and Excitement for the Episode 00:00:12 - Exploring GLP-1 Agonist Non-Responders 00:00:24 - Personal Story: The Impact of Simplicity 00:02:41 - The Importance of Evaluating Your Surroundings 00:03:33 - Understanding Non-Responders: The Nutrition Audit 00:04:05 - Conducting a Nutrition Audit 00:05:39 - Basal Metabolic Rate Explained 00:07:16 - Caloric Intake and Weight Loss 00:08:19 - Leptin Resistance and Its Effects 00:10:07 - Nourishment vs. Muscle Loss 00:10:38 - Key Components of a Nutrition Plan 00:11:55 - Time and Patience in Weight Loss 00:12:58 - Setting Realistic Expectations 00:16:44 - Understanding Muscle Loss Concerns 00:18:48 - Phases of Weight Loss and Expectations 00:20:38 - Conclusion and Upcoming Episode Teaser 00:21:10 - Promoting Fitness and Coaching Programs