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In this video, Dr. Doug Lucas discusses the impact of GLP-1 drugs, such as semaglutide and tirzepatide, on bone health. He reviews various studies, both animal and human, to assess how these drugs affect bone turnover markers and overall bone health. Dr. Doug emphasizes the need for more research to understand the long-term effects of these medications and shares insights from his clinical experience with patients using these drugs. He concludes by stressing the importance of a holistic approach to bone health, rather than relying solely on medication. *STUDIES* https://pubmed.ncbi.nlm.nih.gov/31967113/ https://www.semanticscholar.org/paper/Chronic-administration-of-Glucagon-like-peptide-1-Pereira-Jeyabalan/53ed188a6ec91cc391e1f51f0b88677f6846a45b?utm_source=consensus https://www.semanticscholar.org/paper/A-Pilot-Study-Showing-Acute-Inhibitory-Effect-of-on-Nissen-Marstrand/35d921df93a9401d4cb94a8435c8a10383c7f4a0?utm_source=consensus https://www.semanticscholar.org/paper/GLP-1-Receptor-Agonist-Treatment-Increases-Bone-and-Iepsen-Lundgren/a73891c7cdf9a91976a78d61cbf4efdc410e8cdf?utm_source=consensus https://www.semanticscholar.org/paper/Separate-and-Combined-Effects-of-GIP-and-GLP-1-on-Bergmann-Lund/e118cf9b0a74dd9c461f0fc94447a4c60fdc0eaf?utm_source=consensus https://www.semanticscholar.org/paper/Effects-of-Glucagon-Like-Peptide-1-Receptor-Agonist-Kim-Choi/4aeb6dd5628cfce20f64fd39b82b3276ca9e02dd?utm_source=consensus 🩺⚡️ *INTERESTED IN OUR OPTIMAL BONE HEALTH PROGRAM?* Click the link below to speak with a team member! Click here: https://www.optimalhumanhealth.com/membership 🦴⚡️ *SIGN UP FOR MY FREE MASTERCLASS USING THE LINK BELOW!* Click here: https://www.optimalhumanhealth.com/build-bone Masterclass details: Hosted by Doug Lucas, DO, Board Certified Orthopedic Surgeon and Anti-Aging Specialist, you'll gain insight into the lifestyle, nutrition, testing, and medical solutions for Osteoporosis management and yes, possibly, even reversal. 💻⚡️ *OSTEOCOLLECTIVE:* https://www.optimalhumanhealth.com/osteocollective 📖 ⚡️*Get my book "The Osteoporosis BreakThrough"* https://bit.ly/OsteoporosisBreakthrough I would be grateful if you could consider sharing your thoughts by leaving a review once you've had a chance to read it. Your feedback can inspire others on their own path to bone health excellence. https://bit.ly/LeaveABookReveiw 💻⚡️ *FOR MORE RESOURCES* https://www.drdouglucas.com ▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️▪️ This channel is focused on Bones, Hormones, and Healthspan to help midlife women and beyond aim for optimal, not average, and reignite their spark! The videos on this channel will be focused around helping women navigate healthspan and longevity through the lens of osteoporosis, perimenopause, and menopause. When it comes to osteoporosis and menopause providers and educators often get tunnel vision and your symptoms might get better, but if you don't keep longevity in mind, symptom improvement may come at the expense of heart and brain health. Subscribe and follow along as Dr. Doug Lucas explores the research and clinical applications surrounding women's health. *ABOUT DR. DOUG LUCAS* Dr. Doug Lucas: Owner/founder of Optimal Bone Health and Optimal Human Health. My team and I work together to create custom bone optimization plans for individuals based around supplements, hormone optimization, peptides and more in order to increase bone health and longevity! Optimal Bone Health: https://www.optimalhumanhealth.com/ Instagram: https://www.instagram.com/dr_douglucas/ Facebook: https://www.facebook.com/DrDougLucas/ Linkedin: https://www.linkedin.com/in/doug-lucas-b0243522/ #osteoporosis #exercise #healthspan *Watch and Enjoy! Dr. Doug Lucas Key Moments in this Episode* ========================= Chapters 00:00 Introduction to GLP-1 Drugs and Bone Health 07:53 Research Findings on GLP-1 Drugs and Bone Turnover 12:39 Clinical Experience and Future Directions

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A lean-looking Elon Musk revealed Wednesday that he uses Mounjaro — after previously expressing support for similar weight-loss drugs as a means to curb America’s obesity epidemic. The billionaire Tesla, SpaceX and X boss made the admission in a social media post, where he included an image of himself donning a Santa Claus suit and flowing white beard. Musk dubbed himself “Ozempic Santa” in the X post, noting it’s “Like Cocaine Bear, but Santa and Ozempic!” “Technically, Mounjaro, but that doesn’t have the same ring to it,” he clarified. Mounjaro, like Ozempic, is a GLP-1 inhibitor – a class of drugs developed to help people with diabetes regulate their blood glucose and insulin levels. However, Americans have increasingly been using GLP-1 inhibitors to successfully shed pounds. Musk, 53, noted that he prefers Mounjaro to Ozempic because taking “high doses” of the latter drug made him “fart & burp like Barney from the Simpson’s.” “Mounjaro seems to have fewer side effects and be more effective,” the incoming head of President-elect Donald Trump’s Department of Governmental Efficiency said. Musk has long argued for widespread use of GLP-1 inhibitors to combat obesity – a position that clashes with Health and Human Services Secretary-designate Robert F. Kennedy Jr.’s stance on the medication. Kennedy, 70, has contended that getting Americans to eat healthier would be a more cost-effective way of handling the obesity crisis. Musk’s support for GLP-1 inhibitors has earned him praise from the liberal hosts of “The View,” one of whom, Whoopi Goldberg, has also admitted taking Mounjaro. “Elon’s right on this!” Goldberg declared during a discussion earlier this month on the division between the incoming DOGE chief and HHS secretary.

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Semaglutide is a medication that has been gaining attention lately for its potential to aid in weight loss. This drug, originally developed to treat Type 2 diabetes, has been found to also have a significant impact on weight reduction in both diabetic and non-diabetic patients. But how exactly does semaglutide cause weight loss? In this article, we will explore the mechanisms behind this weight-loss effect, as well as its potential benefits and side effects.

Mechanism of action

Semaglutide belongs to a class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists. These drugs mimic the action of GLP-1, a hormone produced in the gut that helps regulate blood sugar levels and appetite. By activating the GLP-1 receptors in the brain, semaglutide can reduce hunger and increase feelings of fullness, leading to a decrease in calorie intake.

In addition to its effects on appetite, semaglutide also has metabolic effects that contribute to weight loss. It can slow down the emptying of the stomach, which helps to control blood sugar levels and reduce spikes in insulin. This can lead to a decrease in fat storage and an increase in fat burning, ultimately resulting in weight loss.

Furthermore, semaglutide has been shown to improve insulin sensitivity and reduce inflammation in the body. These effects can help to decrease the accumulation of fat in the liver and other organs, leading to a further reduction in body weight. By targeting multiple pathways involved in weight regulation, semaglutide offers a comprehensive approach to weight loss.

Benefits of semaglutide for weight loss

Studies have shown that semaglutide can lead to significant weight loss in obese individuals, with some patients losing up to 15-20% of their body weight. This exceeds the weight loss achieved with other weight-loss medications currently available on the market. In addition to its weight-loss effects, semaglutide has also been shown to improve other metabolic parameters, such as blood sugar control and cholesterol levels.

Another benefit of semaglutide is its convenience and ease of use. Unlike some weight-loss medications that require frequent dosing or injections, semaglutide is administered once a week through a subcutaneous injection. This makes it a more practical option for patients who struggle to adhere to complex medication regimens.

Furthermore, semaglutide has been found to have a positive impact on overall health and well-being. In addition to weight loss, patients taking semaglutide have reported improvements in their quality of life, energy levels, and mood. These benefits can help to motivate patients to continue their weight-loss journey and maintain their results in the long term.

Side effects of semaglutide

While semaglutide is generally well-tolerated, like any medication, it can cause side effects in some individuals. The most common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation. These side effects are usually mild and tend to improve over time as the body adjusts to the medication.

In rare cases, semaglutide can also cause more serious side effects, such as pancreatitis or thyroid tumors. It is important for patients taking semaglutide to be aware of these potential risks and to discuss them with their healthcare provider. Regular monitoring and follow-up care can help to ensure the safe and effective use of semaglutide for weight loss.

In conclusion, semaglutide offers a promising option for individuals looking to achieve weight loss and improve their overall health. By targeting multiple pathways involved in weight regulation, semaglutide can help to suppress appetite, increase feelings of fullness, and promote fat burning. While the medication is not without side effects, its benefits may outweigh the risks for many patients. With further research and clinical experience, semaglutide may become a valuable tool in the fight against obesity and related metabolic conditions.

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