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340 Pounds Down with Zepbound! Jamie Tells the Truth About GLP-1s Downsized Dish with Jamie Selzler – How He Lost 340 Pounds on Zepbound In this episode of The Downsized Dish, Christopher Durham sits down with Selzler, who shares how he lost 340 pounds using the GLP-1 medication Zepbound. Jamie opens up about his experience starting at 652 pounds, the emotional and physical toll of living with severe obesity, and the mindset that helped him transform his life. Filmed in Annapolis, Virginia, during the Your Weight Matters National Convention hosted by the Obesity Action Coalition, this is one of the most honest and inspiring conversations we’ve had. Jamie talks about how he started his GLP-1 treatment with Wegovy, transitioned to Zepbound due to shortages, and has stayed on the medication for nearly two years. Christopher and Jamie cover everything from food noise, and self-discipline to the toxic expectations of diet culture. Jamie explains why exercise wasn't possible at first and how he slowly rebuilt mobility over time. He also shares how he’s shifted his focus from goal weight to input goals like hydration, movement, and consistency. Topics include: • Why it took three months to see results on GLP-1 medication • What to expect with side effects like constipation, fatigue, and food sensitivity • How to keep promises to yourself and build momentum • The power of non-scale victories • Why motivation fades and consistency matters more • Jamie’s plan to hike 20 miles by the end of the year This is a must-watch for anyone treating obesity with GLP-1s or thinking about starting. Jamie brings clarity, encouragement, and practical advice for real people facing real struggles. Follow Jamie on social media and reach out if you need support. His message is simple and powerful: You are not alone, and you deserve a better life. FOLLOW JAMIE: YOUTUBE: @jselzler TikTok: @jamselz IG: @jselzler DOWNSIZED LINKS: Shop our GLP-1 companion products: https://thedownsized.org/downsized-store Visit our website: https://thedownsized.org/ Join us for the Downsized at Sea Cruise 2026: https://thedownsized.org/downsized-at-sea-2026/ Become a channel member and unlock exclusive perks: https://www.youtube.com/@thedownsized/join For sponsorships, brand deals, and press inquiries: https://thedownsized.org/contact/ 00:00 Introduction and Welcome 00:11 Meet Jamie: A Special Guest 00:45 Disclaimer and Social Media Plugs 01:50 Jamie's Weight Loss Journey 02:08 The Role of GLP-1 Medication 02:30 Challenges and Public Speaking 03:04 Mind Pump Podcast Appearance 04:56 Life Changes and Non-Scale Victories 11:33 Exercise and Mobility 17:53 Mindset and Motivation 27:48 Setting Achievable Input Goals 30:52 The Importance of Self-Compassion 32:43 The Journey to Weight Loss 35:07 The Role of GLP-1 Medication 37:04 Managing Side Effects 40:24 Personal Experiences and Advice 42:56 The Emotional Impact of Weight Loss 48:59 Future Goals and Reflections 52:32 Final Thoughts and Encouragement
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L. Reuteri strain 🛒 https://drbrg.co/3ZL8TCH **I am finding that using only ONE TBS of fiber (inulin) in the recipe makes a better-quality product. SUPER GUT BOOK LINK: https://amzn.to/4dIxTy2 How to Make It: https://drdavisinfinitehealth.com/2019/07/how-to-make-l-reuteri-yogurt-step-by-step MICROBIOME MASTER CLASS WEBSITE: https://innercircle.drdavisinfinitehealth.com/Default.aspx Yogurt Maker - https://lvnta.com/lv_lrJY1A8ZLtxmwUpYdX Yogurt Jars - https://lvnta.com/lv_qB2B90JNh0hQjaMoXk Yogurt Containers - https://lvnta.com/lv_SFt3wnanoNkBHrf0Rs Dr. William Davis YouTube Channel: https://www.youtube.com/@WilliamDavisMD DATA: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9796968/ https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2023.1149185/full https://www.nature.com/articles/s41398-020-0855-1 https://www.en-journal.org/journal/view.html?uid=639 Could your depression and anxiety be caused by a missing microbe in your gut microbiome? In this video, I’ll share new, surprising information about L. reuteri, one gut microbe that could eliminate depression symptoms and boost your health in many ways. For more details on this topic, check out the full article on the website: ➡️ https://drbrg.co/4gsrrxC 0:00 Introduction: Depression and gut health 1:17 Depression and anxiety and the microbiome 2:58 Dr. William Davis’ probiotic protocol 4:38 L. reuteri benefits 6:00 Dr. William Davis and lactobacillus reuteri 8:27 L. reuteri benefits in rats 10:58 Dr. Davis’s L. reuteri yogurt recipe 13:19 L. reuteri yogurt for skin health 16:18 Lactobacillus reuteri explained 17:47 SIBO and L. reuteri 24:23 How to make L. reuteri yogurt The vagus nerve acts as a two-way highway between the gut microbiome and the brain. Depression and anxiety can negatively affect the gut microbiome, while problems with the gut can cause depression and anxiety. The good bacteria in the microbiome maintain and support the gut wall and keep bad bacteria in check. Antibiotics, herbicides like glyphosate, junk food, medication, stress, alcohol, pollution, and smoking diminish the microbiome. This results in fewer neurotransmitters, an alteration of blood sugar, the migration of pathogens into the small intestine, SIBO, inflammation, leaky gut, and allergies. Dr. William Davis has developed an amazing protocol for growing your own probiotics. Dr. Davis studied the work of Dr. Irina Conboy, who isolated the benefits of the microbe L. reuteri in experiments with rats. Rats given L. reuteri experience anticancer effects, a better coat, improved healing time, improved muscle tone, increased mating behavior, and an amplified immune system. All the benefits observed in rats also proved true in humans. To make L. reuteri yogurt, combine one probiotic tablet of L. reuteri, inulin prebiotic fiber, and 2 tablespoons of organic half-and-half, and mix into a paste. Once mixed, add a quart of half and half and combine thoroughly. Add this mixture to a yogurt maker and cook at 99 degrees for 36 hours. Consume a half cup per day! You can also try adding vanilla and berries or a low-carb sweetener. Dr. Eric Berg DC Bio: Dr. Berg, age 59, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan, and is the Director of Dr. Berg Nutritionals. He no longer practices, but focuses on health education through social media. Follow Me On Social Media: YouTube: https://www.youtube.com/@Drberg/ YouTube Shorts: https://www.youtube.com/@UCpWhiwlOPxOmwQu5xyjtLDw Facebook: https://www.facebook.com/drericberg Instagram: https://www.instagram.com/drericberg/ Spotify Podcast: 🎧 https://drbrg.co/DrBerg-Spotify TikTok: https://www.tiktok.com/@drbergofficial X: https://x.com/dr_ericberg Disclaimer: Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients, so he can focus on educating people as a full-time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose, and it is not a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Thanks for watching! I hope this increases your awareness about the fascinating benefits of L. reuteri. I’ll see you in the next video.
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In this episode of the Doce Podcast, host Mariana Carrazco welcomes two experts in the field: Dr. Edwin Davila, a physician specializing in Internal Medicine, Exercise Prescription, and Obesity Medicine, and Pharmacist Christopher Freeman. Together, they explore the world of GLP-1 and related weight loss medications. As a patient, Mariana engages in a conversation that unpacks essential information about GLP-1 medications—what they are, how they work, and what listeners should know before considering them for their weight loss journey. This episode covers: Understanding GLP-1 Hormones: Dr. Davila explains what GLP-1 hormones are and the various types of medications available, including Semaglutide and Tirzepatide. Mechanisms and Effectiveness: Listeners will discover how these medications work and the differences in their mechanisms and effectiveness, as explained by Dr. Freeman. Risks and Side Effects: The episode highlights potential risks and side effects of GLP-1 medications, along with dosing recommendations. Comparative Insights: Dr. Davila shares how GLP-1 medications compare to other weight loss methods and addresses common misconceptions surrounding them. Long-term Effects: The experts discuss what users can expect in terms of long-term effects when using these medications. Whether considering GLP-1 medications for weight loss or seeking to understand their function, this episode is packed with valuable insights and practical tips. Tune in to navigate through everything listeners need to know about GLP-1 medications! Follow Dr. Davila on Instagram at @drdavila_do Follow Dr. Chris Freeman on Instagram at @FreemanFit
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Metabolic Treatment Resources: https://brainenergy.com/ https://www.metabolicmind.org/ Lauren's Channel: https://www.youtube.com/channel/UCENqBB_xNax3mLX_WGLf2Lg Learn the skills to Regulate your Emotions, join the membership: https://courses.therapyinanutshell.com/membership Can the Keto Diet Revolutionize Mental Health Treatment? Emerging research suggests that metabolic treatments like the ketogenic diet could be groundbreaking for mental health. Traditionally used to manage epilepsy, the keto diet—a high-fat, low-carb, moderate-protein approach—induces ketosis, a state where the body uses fat as its primary energy source. This metabolic shift may improve brain function by stabilizing neuronal activity, reducing inflammation, and enhancing mitochondrial health. These benefits are now being explored for severe mental health conditions like bipolar disorder, schizophrenia, and depression. One study found that 43% of patients with severe psychiatric disorders achieved remission on a medical ketogenic diet, and all participants experienced symptom improvement. Stories like Lauren Kennedy West’s—who used keto to manage her schizoaffective disorder and eventually stopped psychiatric medications—highlight its transformative potential. Harvard psychiatrist Dr. Chris Palmer theorizes that mental illnesses are rooted in metabolic dysfunction. By addressing underlying metabolic issues, interventions like keto, intermittent fasting, and exercise could revolutionize treatment. However, while the results are promising, challenges remain. Adherence to keto can be difficult, and long-term effects on gut health and nutrient balance require further research. Metabolic treatments offer hope and a fresh perspective for those seeking alternatives to traditional mental health approaches. Always consult a professional before trying such interventions. Looking for affordable online counseling? My sponsor, BetterHelp, connects you to a licensed professional from the comfort of your own home. Try it now for 10% off your first month: https://betterhelp.com/therapyinanutshell https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2022.951376/full https://www.sciencedirect.com/science/article/pii/S0165178124001513?via%3Dihub https://www.npr.org/sections/health-shots/2024/01/27/1227062470/keto-ketogenic-diet-mental-illness-bipolar-depression https://www.psychologytoday.com/intl/blog/diagnosis-diet/202207/new-study-serious-mental-illness-improves-ketogenic-diet https://www.psychologytoday.com/us/blog/advancing-psychiatry/201909/making-sense-nutritional-psychiatry https://www.cambridge.org/core/journals/bjpsych-open/article/ketosis-and-bipolar-disorder-controlled-analytic-study-of-online-reports/24F5057C04622AB3306F638F3FFB7D65 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120987/ 00:00 Intro 01:18 Why Keto You May Ask? 01:46 What Is A Medical Keto Diet? 02:24 Keto and Mental Health 08:07 Is It Practical? Click below to access the transcript: https://therapyinanutshell.com/keto-cure/ FREE Mental Health Resources: https://courses.therapyinanutshell.com/free-resources Check out my podcast, Therapy in a Nutshell: https://tinpodcast.podbean.com/ Therapy in a Nutshell and the information provided by Emma McAdam are solely intended for informational and entertainment purposes and are not a substitute for advice, diagnosis, or treatment regarding medical or mental health conditions. Although Emma McAdam is a licensed marriage and family therapist, the views expressed on this site or any related content should not be taken for medical or psychiatric advice. Always consult your physician before making any decisions related to your physical or mental health. In therapy I use a combination of Acceptance and Commitment Therapy, Systems Theory, positive psychology, and a bio-psycho-social approach to treating mental illness and other challenges we all face in life. The ideas from my videos are frequently adapted from multiple sources. Many of them come from Acceptance and Commitment Therapy, especially the work of Steven Hayes, Jason Luoma, and Russ Harris. The sections on stress and the mind-body connection derive from the work of Stephen Porges (the Polyvagal theory), Peter Levine (Somatic Experiencing) Francine Shapiro (EMDR), and Bessel Van Der Kolk. I also rely heavily on the work of the Arbinger institute for my overall understanding of our ability to choose our life's direction. And deeper than all of that, the Gospel of Jesus Christ orients my personal worldview and sense of security, peace, hope, and love https://www.churchofjesuschrist.org/comeuntochrist/believe If you are in crisis, please contact the National Suicide Prevention Hotline at https://suicidepreventionlifeline.org/ or 1-800-273-TALK (8255) or your local emergency services. Copyright Therapy in a Nutshell, LLC
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The ketogenic diet has taken the health and wellness world by storm in recent years, with many people swearing by its ability to help them lose weight, improve their energy levels, and support overall health. Keto-friendly products have been flooding the market, each claiming to offer a unique solution for those following a ketogenic lifestyle. One such product, QE Keto, has recently gained widespread attention after appearing on the hit TV show Shark Tank. With its innovative approach to supporting ketosis and weight loss, QE Keto has quickly become a favorite among keto enthusiasts.
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On a recent episode of Shark Tank, the founders of QE Keto stepped into the tank to pitch their innovative product to the sharks. Their pitch focused on the unique formulation of QE Keto, which is designed to support ketosis and help users reach their weight loss goals. The sharks were impressed by the science behind QE Keto and the testimonials from satisfied customers who had seen real results while using the product.

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Since appearing on Shark Tank, QE Keto has experienced a surge in popularity, with many viewers eager to try the product for themselves. The exposure from the show has helped increase awareness of QE Keto and its benefits, leading to a growing number of satisfied customers who have seen positive results while using the product. As the ketogenic diet continues to gain popularity, products like QE Keto are likely to become even more sought after by those looking to enhance their keto journey.
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Believe it or not, if you're using one of the pharmaceutical-based GLP-1 drugs, about 30% of the weight that you lose is from bone and muscle. This matters because as you age, it becomes much harder to regenerate bone and muscle (which makes up a lot of your metabolism). Using these drugs leaves you with a slower metabolic rate than when you started and you become dependent on these drugs long-term. If you truly want to lose weight (and keep it off) the healthy way, I highly suggest checking out a 21-Day Functional Medicine Detox and creating healthy lifestyle choices. Some of our clients lose up to 15 pounds (or more) in 21 days and completely turn their health around. Comment "READY" below and I'll send you our private client link to get started. You can tune into today's full podcast to learn more about weight loss at https://www.StephenCabral.com/3358
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