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What is Ozempic?
Ozempic (semaglutide) is used for type 2 diabetes in adults to improve blood sugar levels and also used to lower the risk of major cardiovascular events like stroke, heart attack or death, for adults with type 2 diabetes with heart disease. In clinical trials, Ozempic has also been shown to help with weight loss, after 30 weeks, patients on Ozempic 0.5mg had lost 2.6 kg more than the placebo group, and patients on Ozempic 1mg lost 3.5 kg more than the placebo group. Although currently, Ozempic is not an FDA-approved weight loss medicine.
Ozempic works to lower blood sugar, helping the pancreas make more insulin, decreasing the amount of sugar your liver makes, and slowing the rate food passes through your body, making you feel full longer. Ozempic is from a class of medicines called a glucagon-like peptide-1 (GLP-1) agonists (incretin mimetics) that works by binding to GLP-1 receptors which results in lower blood sugar levels and A1C levels and may also reduce your appetite to help weight loss.
Ozempic is a once-weekly injection that should be used along with diet and exercise. Ozempic should not be used for type 1 diabetes mellitus.
Other brands of semaglutide.
Ozempic (semaglutide) contains the same active ingredient as:
Wegovy injections which is FDA approved for weight loss in adults and teenagers who have obesity, or adults who are overweight (excess weight) and also have weight-related medical problems.
Rybelsus tablets, which are FDA approved to lower blood sugar levels for type 2 diabetic patients along with diet and exercise.
Ozempic side effects
Common Ozempic side effects
low blood sugar (in people with type 2 diabetes);
upset stomach, heartburn, burping, gas, bloating;
nausea, vomiting, stomach pain, loss of appetite;
diarrhea, constipation;
runny nose or sore throat;
stomach flu symptoms; or
headache, dizziness, tiredness.
Serious Ozempic side effects.
Get emergency medical help if you have signs of an allergic reaction: hives, itching; dizziness, fast heartbeats; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
vision changes;
unusual mood changes, thoughts about hurting yourself;
pounding heartbeats or fluttering in your chest;
a light-headed feeling, like you might pass out;
signs of a thyroid tumor--swelling or a lump in your neck, trouble swallowing, a hoarse voice, feeling short of breath;
symptoms of pancreatitis--severe pain in your upper stomach spreading to your back, nausea with or without vomiting, fast heart rate;
gallbladder problems--upper stomach pain, fever, clay-colored stools, jaundice (yellowing of the skin or eyes);
low blood sugar--headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery;
kidney problems--swelling, urinating less, blood in urine, feeling tired or short of breath
stomach flu symptoms--stomach cramps, vomiting, loss of appetite, diarrhea (may be watery or bloody)
symptoms of ileus (stomach paralysis)--bloating, stomach cramps or pain, nausea or vomiting, constipation or diarrhea, loss of appetite.
How should I use Ozempic?
Use this medicine exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. It is usually started at a low dose that is gradually increased every 4 weeks to 30 days. Follow your doctor's dosing instructions very carefully, and ask your doctor or pharmacist if you need help.
Ozempic is injected under the skin (subcutaneous injection), usually once per week at any time of the day, with or without food. Use an injection on the same day each week.
Prepare an injection only when you are ready to give it. Call your pharmacist if the medicine looks cloudy, has changed colors, or has particles in it.
Your healthcare provider will show you where to inject this medicine, it is usually injected into the abdomen, thigh, or upper arm. Do not inject into the same place two times in a row.
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