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Orforglipron also reduced blood sugar levels in participants with type 2 diabetes A significant trial of a daily weight-loss pill has found that it helped people to shed the pounds and reduce their blood sugar levels, making it a contender to join the new wave of drugs that combat obesity and diabetes. People who took a 36mg pill of orforglipron lost an average of 7.3kg (16lbs) over nine months, according to results from a phase 3 clinical trial reported by the drug’s manufacturer, Eli Lilly, on Thursday. The trial, which enrolled 559 obese people with type 2 diabetes from the US, China, India, Japan and Mexico, also found that the daily pill reduced blood sugar levels, in some cases bringing them below the formal threshold for diabetes. Results from the trial have been eagerly awaited by health researchers. Orforglipron is a daily pill version of a GLP-1 agonist, the medication used in blockbuster weight-loss injections such as Ozempic and Wegovy. David Ricks, Eli Lilly’s chief executive, said: “As a convenient once-daily pill, orforglipron may provide a new option and, if approved, could be readily manufactured and launched at scale for use by people around the world.” In a statement accompanying the results, the company said the drug met expectations on safety, tolerability, glucose control and weight loss. While weight-loss jabs have soared in popularity, health officials believe that daily pill versions of the medicine could allow more people to control their weight and blood sugar levels. In Britain, two-thirds of adults are either overweight or living with obesity and more than 5 million people have type 2 diabetes. The 40-week trial showed that taking a daily pill of 3mg, 12mg or 36mg reduced blood sugar by 1.2% to 1.5%. During the same period, participants saw their weight drop by an average of 4.5% on the 3mg pill, 5.8% on the 12mg pill and 7.6% on the 36mg pill. The results will be presented at a meeting of the American Diabetes Association in June before publication in a peer-reviewed journal. The company said it would apply for approval to market the drug for weight management later this year and for type 2 diabetes next year. Naveed Sattar, a professor of cardiometabolic medicine at the University of Glasgow, said: “These are important results. Having new oral agents that lower glucose but also meaningfully lower weight well beyond levels seen with most existing diabetes therapies is critical to future type 2 diabetes care. Of course, one caveat is that we do not know the effects of this newer therapy on cardiovascular outcomes but this will be forthcoming in future trials.” - The Guardian

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You dont have to eat less to loose weight. Swapping your calorie dense foods for quality whole foods will have you eating a lot more food with less calories naturally. Just by eliminating sugar and processed foods many find that weight comes off at a rapid weight and they are left feeling more satisfied I’m NOT saying anything in the 1500 calorie plate is “unhealthy” Focusing on whole fruits, veggies and protein will allow you to have more volume to your food keeping you satisfied longer 🍏 Whole Foods vs. Processed Foods: Discover the power of natural nutrition! Whole foods provide essential nutrients without the additives found in processed options. Choose whole for a healthier you! #WholeFoods #HealthyEating 🍟 Impact of Ultra-Processed Foods on Weight Loss: These sneaky saboteurs can derail your weight loss goals. High in empty calories and low in nutrients, ultra-processed foods make it harder to shed pounds. Stay informed, stay healthy! #UltraProcessed #HealthyEating 🥗 Strategies for Low-Calorie High-Volume Eating: Fill your plate with nutrient-dense, low-calorie foods to stay full and satisfied. Think leafy greens, veggies, and lean proteins to maximize volume without the calories! #LowCalorie #HealthyEating 🍬 High Sugar Diet and Metabolism: High sugar intake can wreak havoc on your metabolism, leading to weight gain and energy crashes. Opt for natural sugars and balanced meals to keep your metabolism in check! #HighSugar #HealthyEating 🌿 Whole Foods Benefits for PCOS: Whole foods can be a game-changer for managing PCOS symptoms. Rich in fiber, antioxidants, and healthy fats, they support hormonal balance and weight management. #WholeFoods #PCOSWeightLoss 🐢 Slow Weight Loss Solutions: Consistent, gradual weight loss is sustainable and healthier for your body. Focus on balanced meals, regular exercise, and mindful eating to achieve long-term success! #HealthyEating #PCOSWeightLoss : #WholeFoods #UltraProcessed #HealthyEating #LowCalorie #HighSugar #pcosweightloss

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READ ABOUT WHY PERIMENOPAUSE SUPPLEMENTS ARE DIET CULTURE GARBAGE HERE: https://fitbottomedgirls.com/2025/05/perimenopause-profit-and-pills-the-truth-about-menopause-supplements/ ** A few years ago, I started to see a lot of weird ads in my feed. I couldn't quite tell what they were at first. Then I realized I was getting ads for perimenopause supplements. ** All of these supplements make a wide array of promises: support hormonal balance relieve symptoms of menopause support cortisol/estrogen/progesterone levels improve sleep quality help with irritability enhance the body’s stress response support mental function and of course, promote healthy weight loss and curb carb cravings. ** First of all, a single pill can't actually do all of that. Especially not when it's full of a "proprietary blend" of herbs that are not necessarily meant to interact with one another. Second, supplements are deeply problematic because they are unregulated, which means they are largely untested. Which means, you don't really know what they're going to do to your body. Third, why do they all promote "healthy weight loss?" Why are we still prioritizing being smaller at a time when your body is in full chaos? How does that help? ** I wrote an entire essay about how perimenopause supplements are diet culture garbage for Fit Bottomed Girls. If you're not already following that platform, it's my favorite place to write about health and fitness, while pushing back against the mainstream, diet culture narrative that permeates so much of what we hear. ** Please go follow them, subscribe to FBG (via their website) to receive articles like mine delivered to your inbox. And if you're going through perimenopause or will someday, please read my piece, linked up top. It's an important one.

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Wondering if weight loss medications like Ozempic and Mounjaro are a one-way ticket to long-term success? Dr. Charles Cavo, a leading expert in metabolic health, shares the truth about these drugs and why lifestyle changes are the real game-changer! Let’s dive into what you need to know about their role, their limits, and why a sustainable approach is key to lasting health. 1️⃣ Temporary Assistance: Ozempic, Mounjaro, and similar drugs are designed to give you a jump-start, helping with weight loss and metabolic improvements. 2️⃣ Lifestyle Matters: Medications are only part of the equation. Lifestyle changes are essential for long-term success, and those who rely solely on drugs may not maintain their results. 3️⃣ Not Forever: These medications are not intended for lifelong use. Many people use them temporarily to get on track with their health goals, with the aim of transitioning to more sustainable habits over time. 4️⃣ Personalized Approach: Dr. Cavo stresses that there’s no “one-size-fits-all.” The long-term use of these medications depends on individual needs and circumstances. If you’re considering weight loss medications or struggling with metabolic health, remember that balance and lifestyle integration are key for lasting change! #MetabolicHealth #WeightLossJourney #Ozempic #Mounjaro

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Want to lose BODY FAT and get LEAN? It’s the simple things done consistently that will really help you! 1 - Walk more 2 - Eat more nutrient dense, high volume, low calorie foods 3 - Drink more water 4 - Do regular resistance training 5 - Sleep more #CrockFitCommunity using my app, following these will help you on your journey. You’ve got your workout plan and your nutrition guide, so keep going! Join my #CrockFitApp to get better results! Www.crockfitapp.com Click links in bio 👊 #fitness #fitnessuk #bodyfat #burnfat #fatloss #weightloss #fitnessmotivation #healthy #healthyuk #menshealth #mensfitness #fullbodyworkouts #nutrition #bodyweightworkouts #shorts #fitnessshorts #crockfit

Shania Twains 50 Pound Weight Loss Her Diet Workout And Secret To Confidence

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Rosie O Donnell Reveals Weight Loss Transformation After Using Mounjaro

Imagine losing weight only to find unexpected surprises beneath the skin. It’s a common misconception that shedding pounds will erase all imperfections, but lipomas are different from regular fat cells—they remain visible no matter how much weight you lose. Renowned dermatologist Dr Sandra Lee faces a patient struggling with extra lipomas around his waist. Will she help him regain his confidence and tackle these stubborn growths? Tune in to Dr. Pimple Popper, on TLC. Subscribe Now! https://www.youtube.com/channel/UC66XnXiG_K0-vKBqZ84aijQ?sub_confirmation=1 📺 Watch More Of Dr. Pimple Popper Videos: https://www.youtube.com/playlist?list=PLrgsnBjwzcf4V9vNK9j8crIv-JGNCfeaI Do Not forget to LIKE, Share and Comment on our videos. Also follow us on: Facebook: https://www.facebook.com/TLCIndiaOfficial/ Twitter: https://twitter.com/TLCINOfficial Instagram: https://www.instagram.com/tlc_india/ #pimplepoppingshorts #realityshow #drlee #DrSandraLee #realstory #pimple #pimplepopping #pimplepopper