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Click Here to Subscribe: http://Bit.ly/ThomasVid Find Good Culture in Whole Foods: https://www.goodculture.com My Website: http://ThomasDeLauer.com Belly Fat | Top 5 Causes of Belly Fat for MEN [2019] (Fat Loss 101) 1) Not enough Salt and Glucocorticoids (cortisol) out of balance Salt & Cortisol: Low sodium levels cause an increase in aldosterone, an adrenal hormone that seeks to preserve sodium in the body when it’s perceived to be scarce - aldosterone is responsible for telling the kidneys to retain the salt that your body needs. In other words, a lack of sodium can cause the brain to send signals to the adrenal glands to increase the release of aldosterone, which is responsible for water balance - cortisol is released alongside aldosterone. Cortisol & Belly Fat: Tissue cortisol concentrations are controlled by a specific enzyme (11-hydroxysteroid dehydrogenase) that converts inactive cortisone to active cortisol. This particular enzyme is located in adipose tissues - the gene for this enzyme is expressed more by obese conditions and has also been demonstrated in research that human visceral fat cells have more of these enzymes compared to subcutaneous fat cells. Thus, higher levels of these enzymes in these deep fat cells surrounding the abdomen may lead to obesity due to greater amounts of cortisol being produced at the tissue level. Additionally, deep abdominal fat has four times more cortisol receptors compared to subcutaneous fat. Cortisol can increase the activity of lipoprotein lipase (LPL), the major fat storing enzyme - there’s more cortisol receptors in visceral fat, hence more LPL activity there. Study – Oncotarget: The randomized, open-label pilot trial was conducted at a single institution. A total of 85 obese people were enrolled. All participants were served meals three times a day, and provided either a low salt diet or control diet with same calorie. Reductions in body weight (–6.3% vs. –5.0%) and BMI (–6.6% vs. –5.1%) were greater in the low salt group than in the control group. Extracellular water and total body water were significantly reduced in the low salt group compared to the control group. However, changes in body fat mass, visceral fat area, and skeletal muscle mass did not differ between the two groups. The observed decrease of body weight was caused by reduction of total body water, not by reduction of body fat mass or visceral fat mass. https://www.ncbi.nlm.nih.gov/pmc/arti... 2) Cardio in a Fed State (benefits of fasted training in general) Fat Loss (Intramyocellular Lipids) & Muscle Growth (P70S6K) Study - The Journal of Physiology: Findings- During F but not during CHO, the exercise bout decreased IMTG content in type I fibres from roughly 18% to 6% area lipid staining. Exercise-induced net glycogen breakdown was similar in F and CHO - however, compared with CHO, mean rate of postexercise muscle glycogen resynthesis was 3-fold greater in F. https://www.ncbi.nlm.nih.gov/pmc/arti... Study - European Journal of Applied Physiology A study from the European Journal of Applied Physiology had subjects split into two groups that were trained on two occasions separated by three weeks - one of the sessions was performed on an empty stomach after an overnight fast. Found: Increased p70s6k phosphorylation during intake of a protein–carb drink following resistance exercise in the fasted state - fasted training group saw a bigger increase in p70s6k. https://link.springer.com/article/10.... 3) Sleep Deprivation - Metabolic Health Study - Public Library of Science: Medicine: In this study, subjects (1,024 ) who consistently slept less than five hours a night had significant differences in the hormones leptin and ghrelin as compared with people who slept an average of eight hours a night. More specifically, subjects suffering a lack of sleep had 16% less leptin and nearly 15% more ghrelin than those who were well rested did. https://www.ncbi.nlm.nih.gov/pmc/arti... Molecular Level (endocannabinoids) Lack of sleep increases activity of endocannabinoid 2-arachidonoylglycerol (2-AG), which is mediated via the CB1 receptor. https://www.ncbi.nlm.nih.gov/pubmed/2... 4) Too Much Fructose: After the 100:0 glucose bolus, fractional lipogenesis rose to only 8%, which is quite low compared with the 23% observed previously (32). After consumption of the 50:50 and 25:75 solutions used here, the peak in lipogenesis was 17%. Lipogenesis increased 2-fold when as little as half the glucose was replaced with fructose. https://academic.oup.com/jn/article/1... 5) Estrogen & Alcohol Study – Toxicology: The study looked to investigate if ethanol alters aromatization of androgens and concentrations of hepatic estrogen and androgen receptors. In rats given ethanol, hepatic aromatization of androgen to estrogen was significantly increased by the ethanol administration. https://www.ncbi.nlm.nih.gov/pubmed/2...
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Fat, on the other hand, isn’t the enemy. It’s your body’s natural energy reserve—a built-in fuel tank designed to power you when energy is scarce. But: • 🛑 If you keep “filling the tank” with excess calories and never tap into those reserves, the tank just keeps expanding. • 🏋️♂️ To burn fat, you need to create a caloric deficit—burning more energy than you consume while staying active. Let’s put cardio into perspective: • 🍦 Eating 400 calories of ice cream takes seconds. Burning those calories? That’s an hour of running. • 🚶♂️ Even 30 minutes of moderate cardio only burns about 250 calories. • ❤️ Cardio is a tool for fitness and heart health—not a replacement for a solid nutrition plan. If you want to shed fat: • 🥗 Dial in your diet: Fuel your body with whole foods and eat in a slight deficit. • 💪 Prioritize strength training: Build muscle to increase your resting metabolism (muscle burns calories even at rest!). • 🚴♀️ Move with purpose: Use cardio to complement your routine, not as the sole focus. Fat isn’t the problem—unused fat is. When you create balance, stay active, and make smart food choices, your body starts using its reserves the way it was meant to. If you like the content, please follow 😊💚 #fatloss #weightloss #fitness #weightlossjourney #health #healthylifestyle #gym #diet #nutrition #workout #motivation #fitnessmotivation #weightlosstransformation #personaltrainer #bodybuilding #transformation #healthy #fit #fitfam #healthyfood #exercise #healthyeating #fatlossjourney #weightlossmotivation #fitnessjourney #fatlosstips #training #healthyliving #weightlosstips #lifestyle
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Semaglutide, a medication that has gained attention in recent years for its effectiveness in treating type 2 diabetes, has now been FDA-approved for the treatment of weight loss. This new approval marks an important milestone in the fight against obesity, a growing health crisis that affects millions of people worldwide. Semaglutide, marketed under the brand name Wegovy, has shown promising results in clinical trials, leading to its approval by the FDA as a safe and effective treatment for weight loss.
What is Semaglutide?
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that works by mimicking the action of a hormone called GLP-1. GLP-1 is produced in the gut in response to food intake and plays a key role in regulating blood sugar levels and appetite. By activating the GLP-1 receptors in the brain, semaglutide helps to reduce appetite and increase feelings of fullness, leading to a decrease in caloric intake and subsequent weight loss.
In addition to its effects on appetite and weight loss, semaglutide also has other beneficial effects, such as improving blood sugar control, lowering blood pressure, and reducing the risk of cardiovascular events. These additional benefits make semaglutide a valuable treatment option for patients with obesity and related comorbidities, such as type 2 diabetes and cardiovascular disease.
Semaglutide is administered via a once-weekly injection under the skin and is typically used in conjunction with diet and exercise to maximize its weight loss effects. The convenience of a once-weekly injection makes semaglutide a practical and easy-to-use treatment option for patients who struggle with adherence to daily medications or frequent doctor visits.
How Does Semaglutide Promote Weight Loss?
Semaglutide promotes weight loss through a variety of mechanisms, including appetite suppression, increased feelings of fullness, and slowing down the emptying of the stomach. By reducing appetite and increasing satiety, semaglutide helps to decrease caloric intake and promote weight loss in individuals with obesity.
Additionally, semaglutide has been shown to improve insulin sensitivity and reduce insulin resistance, leading to better blood sugar control and a lower risk of developing type 2 diabetes. Improved insulin sensitivity also contributes to weight loss by promoting the utilization of glucose for energy production and reducing the storage of fat in the body.
Furthermore, semaglutide has been found to reduce inflammation in the body, which is a common feature of obesity and is associated with an increased risk of chronic diseases such as heart disease, stroke, and certain types of cancer. By reducing inflammation, semaglutide may help to improve overall health and reduce the risk of obesity-related complications.
Who Can Benefit from Semaglutide?
Semaglutide is recommended for individuals with a body mass index (BMI) of 30 kg/m² or higher, or a BMI of 27 kg/m² or higher with at least one weight-related comorbidity, such as type 2 diabetes, high blood pressure, or dyslipidemia. Patients who have not achieved weight loss with diet and exercise alone or who are unable to undergo bariatric surgery may benefit from treatment with semaglutide.
It is important to note that semaglutide is not a magic bullet for weight loss and should be used in conjunction with a healthy diet and regular exercise to achieve optimal results. Lifestyle modifications, such as increasing physical activity, reducing caloric intake, and improving sleep habits, are essential components of a successful weight loss plan and can enhance the effects of semaglutide.
Individuals who are considering treatment with semaglutide should consult with their healthcare provider to determine if it is a suitable option for them and to discuss the potential risks and benefits of therapy. Close monitoring by a healthcare professional is recommended to ensure safe and effective use of semaglutide and to make any necessary adjustments to the treatment plan as needed.
What Are the Side Effects of Semaglutide?
Like any medication, semaglutide may cause side effects in some individuals, although not everyone will experience them. Common side effects of semaglutide may include nausea, vomiting, diarrhea, constipation, abdominal pain, and decreased appetite. These side effects are usually mild to moderate in severity and tend to improve over time as the body adjusts to the medication.
In rare cases, semaglutide may cause more serious side effects, such as pancreatitis, thyroid tumors, or allergic reactions. Patients should seek medical attention if they experience symptoms such as severe abdominal pain, persistent vomiting, difficulty breathing, swelling of the face or throat, or changes in vision while taking semaglutide.
It is important for patients to inform their healthcare provider of any side effects they experience while taking semaglutide and to follow up regularly to monitor their progress and address any concerns. By working closely with their healthcare team, patients can maximize the benefits of semaglutide while minimizing the risks of treatment.
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Here's What To Do... Trying to loose fat is a natural part of life, if I needed to drop some pounds fast this is EXACTLY what I would do... Increase Strength Training, kind of a no brainer...BUT, strength training creates an afterburn effect which causes your body to continue burning fat even after your workout. Cutting out ALL processed carbs and sugars...This is crucial because those same processed carbs and sugary foods are very calorie dense but not very filling. Therefore, by getting rid of them it makes it much easier to reduce overall calorie intake. High Intensity Interval Training is more beneficial than traditional long duration cardio...This is because it preserves your muscle mass while burning your fat. Instead of everything burning off at once. If you don't know where to start, DM "Fat Loss" and I will get you started. #fitness #fatloss #fitover40 #mensfitness
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