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Tom DeLauer claims Ozempic and keto may share eerily similar effects… but is that really true? Dr. Eric Westman reacts to Tom’s breakdown of GLP-1s vs. low-carb diets. Are you just suppressing appetite — or rewiring your metabolism? What’s the real cost of “easy weight loss”? From visceral fat loss to ketone production, we explore the surprising overlaps and hidden dangers. Could pairing medication with diet unlock a better result — or are we just medicating bad habits? 👁️ Seen a video you'd like me to react to? Leave a comment below or join the YouTube membership for priority comments where your video recommendation will be seen first and any questions you may have will be answered 🎬 For more Reacts Video Click Here: https://www.youtube.com/playlist?list=PL55Chm2jfDSpOrkAYNuux9Pri4k5QmrZu 🟣 If you enjoy my channel and would like to support what I do there are a few different ways you can show your support listed below: 🟣BECOME A CHANNEL MEMBER ON YOUTUBE Receive priority comments, early access to new videos and join livestreams twice a month to ask me anything live! 🟣Support the channel via PayPal if you don't want anyone taking a chunk of what you send me and you can set up a recurring payment https://www.paypal.com/donate/?hosted_button_id=ZDZK4SN7DJYXC 🟣Vist Adapt Your Life Academy https://adaptyourlifeacademy.com/ 🟣Adapt Your Life Academy Online Courses: https://adaptyourlifeacademy.com/all-courses/ 🟣Bestselling Book – END YOUR CARB CONFUSION: https://www.amazon.com/Your-Carb-Confusion-Eric-Westman 🟣END YOUR CARB CONFUSION COOKBOOK: https://www.amazon.com/End-Your-Carb-Confusion 🟣FREE QUIZ to determine your personal carb threshold: https://adaptyourlifeacademy.com/carb-threshold-bonus/ ======================================================================== 🟣MY SOCIAL MEDIA 🟣Like my Facebook Page ➡️ https://www.facebook.com/AdaptYourLifeAcademy 🟣Follow me on Instagram ➡️ https://www.instagram.com/adaptyourlifeacademy/ 🟣Follow me on X ➡️ https://x.com/drericwestman ======================================================================== 🟣Dr. Eric Westman, Associate Professor of Medicine at Duke. He is Board Certified in Obesity Medicine & Internal Medicine, & founded the Duke Keto Medicine Clinic. He is a Fellow in The Obesity Society. He is the author of The New Atkins for a New You, Cholesterol Clarity, and Keto Clarity, and End Your Carb Confusion & co-founder of Adapt Your Life. Disclaimer: Nothing on our channel is medical advice. Dr. Westman and the Adapt Your Life team do not diagnose, treat, cure, or prevent any medical conditions online. We provide education to help people better understand their own health and support their well-being. Make sure you are working with YOUR licensed provider to monitor your health and medications. These posts and videos are not designed to and do not provide medical advice, professional diagnosis, opinion, treatment, or services to you or to any other individual. We do not promote or endorse affiliate links and/or products unless they are our own.

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Semaglutide is a medication that has gained popularity in recent years for its effectiveness in aiding weight loss. Many individuals turn to semaglutide as a treatment option for managing obesity and achieving their weight loss goals. However, one common question that arises is: how long do you stay on semaglutide for weight loss?

Understanding Semaglutide for Weight Loss

Semaglutide is a prescription medication that belongs to a class of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists. It works by mimicking the effects of a hormone in the body called GLP-1, which helps regulate blood sugar levels and reduce appetite. In addition to its benefits for managing type 2 diabetes, semaglutide has also been shown to be effective in promoting weight loss.

When used for weight loss, semaglutide is typically prescribed as a once-weekly injection. The medication works by helping individuals feel full sooner and stay full longer, leading to reduced caloric intake and weight loss over time. It is important to note that semaglutide should be used in conjunction with a healthy diet and regular exercise for optimal results.

Most individuals who use semaglutide for weight loss will start to see results within the first few months of treatment. In clinical trials, participants who took semaglutide experienced significant weight loss compared to those who took a placebo. The amount of weight loss can vary from person to person, but on average, individuals may lose around 5-10% of their body weight with semaglutide.

Treatment Duration and Long-Term Use

When it comes to how long you should stay on semaglutide for weight loss, the duration of treatment can vary depending on individual factors. Some individuals may only need to use semaglutide for a few months to reach their weight loss goals, while others may need to use it for a longer period of time to maintain their weight loss.

It is important to work closely with your healthcare provider to determine the right treatment duration for you. Your doctor will take into account factors such as your starting weight, weight loss goals, overall health, and any potential side effects of the medication when deciding how long you should stay on semaglutide.

In some cases, individuals may choose to use semaglutide for weight maintenance after reaching their initial weight loss goals. This can help prevent weight regain and support long-term success in managing obesity. Your healthcare provider can help you create a plan for transitioning to maintenance therapy with semaglutide if needed.

Potential Side Effects and Considerations

Like any medication, semaglutide can cause side effects in some individuals. Common side effects of semaglutide for weight loss may include nausea, vomiting, diarrhea, and constipation. These side effects are usually mild and improve over time as your body adjusts to the medication.

It is important to talk to your healthcare provider if you experience any bothersome side effects while taking semaglutide. Your doctor may be able to adjust your dosage or recommend strategies to help alleviate side effects. It is also essential to follow your healthcare provider’s instructions carefully when using semaglutide to ensure the best results and minimize potential risks.

Overall, semaglutide can be a valuable tool for individuals who are struggling to lose weight through diet and exercise alone. By working with your healthcare provider to determine the right treatment duration and approach for you, semaglutide can help support your weight loss goals and improve your overall health and well-being.

Conclusion

In conclusion, semaglutide is a promising medication for weight loss that can be used effectively under the guidance of a healthcare provider. The duration of treatment with semaglutide can vary depending on individual factors, and it is essential to work closely with your doctor to develop a personalized treatment plan. By understanding the potential benefits, side effects, and considerations of semaglutide for weight loss, you can make informed decisions about your weight management journey.

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Drs Akshay Jain and Lorenzo Leggio discuss GLP-1 RA therapy and its potential to mitigate alcohol misuse syndrome. https://www.staging.medscape.com/viewarticle/glp-1-ra-therapy-alcohol-use-disorder-2024a1000fur?src=soc_yt --TRANSCRIPT-- Akshay B. Jain, MD: Today we are very excited to have Dr Leggio join us all the way from the National Institutes of Health (NIH). He is an addiction physician scientist in the intramural research program at NIH. Welcome, Dr Leggio. Thanks for joining us. Lorenzo Leggio, MD, PhD: Thank you so much. Jain: We'll get right into this. Your session was, in my mind, extremely informative. The session looked at glucagon-like peptide 1 receptor agonist (GLP-1 RA) therapy and its potential effects on mitigating alcohol misuse syndrome, so, reduction of alcohol addiction potentially. We've seen in some previous clinical trials, including many from your group, that alcohol use is known to be reduced — the overall risk of incidence, as well as recurrence of alcohol use — in individuals who are on GLP-1 RA therapy. Can you share more insights about the data already out there? Leggio: At the preclinical level, we have a very robust line of studies, experiments, and publications looking at the effect of GLP-1 RAs, starting from exenatide up to, more recently, semaglutide. They show that these GLP-1 RAs do reduce alcohol drinking. They used different animal models of excessive alcohol drinking, using different species — for example, mice, rats, nonhuman primates — models that reflect the excessive alcohol drinking behavior that we see in patients, like physical alcohol dependence or binge-like alcohol drinking, and other behaviors in animal models that reflect the human condition. In addition to that, we recently have seen an increase in human evidence that GLP-1 RAs may reduce alcohol drinking. For example, there is some anecdotal evidence and some analyses using social media showing that people on GLP-1 RAs report drinking less alcohol. There are also some pharmacoepidemiology studies which are very intriguing and quite promising. In this case, people have been looking at electronic medical records; they have used the pharmacoepidemiology approaches to match patients on GLP-1 RAs because of diabetes or obesity, and have compared and matched to patients on different drugs as the controls. A study was recently published in Nature Communications by a group in Cleveland in collaboration with Dr Nora Volkow from the National Institute on Drug Abuse. This study shows the association between being on a GLP-1 RA and the lower incidence of alcohol use disorder and lower drinking. There is also some promise from prospective randomized clinical trials. In particular, there was one clinical trial from Denmark, a well-known and -conducted clinical trial where they looked at exenatide, and they didn't see an effect of exenatide compared with placebo in the main analysis. But in a subanalysis, they did see that exenatide reduced alcohol drinking, but only in patients with alcohol use disorder and obesity. This suggests that these medications may work for some patients and not for other patients. That's fine, because just like in any other field in medicine, including diabetes, obesity, hypertension, Parkinson's, and depression, not all medications work for everybody. If these medications will work for alcohol addiction, we do not expect that they will work for everybody. One ongoing question in the field is to try to identify the phenotypes or the subgroup of people who may be more responsive to these medications. Jain: This is such a fascinating field, and all these studies are coming out. In your review of all the literature so far, do you think this is dose dependent? Also, we see that, for instance, with certain individuals, when they take GLP-1 RA therapy, they might have a lot of gastrointestinal (GI) side effects. Recent studies have shown that the rate of these GI side effects does not necessarily correlate with the amount of weight loss. In the alcohol addiction field, do you think that the GI side effects, things like nausea, could also have a potential role in mitigating the alcohol addiction? Leggio: This is a great question. They may play a role; they may contribute, too, but we don't think that they are the driving mechanism of why people drink less, for at least a couple of reasons. One is that, similar to the obesity field, the data we have so far don't necessarily show a relationship between the GI side effects and the reduction in drinking. Plus, the reduction in drinking is likely to happen later when many GI side effects are gone or attenuated. Transcript in its entirety can be found by clicking here: https://www.staging.medscape.com/viewarticle/glp-1-ra-therapy-alcohol-use-disorder-2024a1000fur?src=soc_yt

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