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Dr. Simonds explains how combination drug therapy can break through stubborn weight loss plateaus by using medications that work through different mechanisms—like GLP-1s, phentermine, Topiramate, and metformin. If you’ve been taking just one medication and your progress has slowed, this video is for you. Learn how combining treatments can jumpstart your results and help you get back on track. 💡 What You’ll Learn: -Why weight loss plateaus happen -How combination therapy works -Which medication combinations are most effective -When to consider adding a second (or third) medication -How to take the next step with expert medical support 👉 Ready to move past your plateau? Book your appointment now: https://simondsmetabolics.com/schedule-appointment 📌 Medical Disclaimer: This video is for educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting or changing any medication or treatment plan.

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Can obesity be protective? Can rapid weightloss sometimes be harmful? Is there a hidden cause for why some people stall in weight loss that practically no one knows about? The answer is YES. But here’s a hint, its not diet, exercise, or sleep! In this video we attempt to answer some of those questions, and look at Persistent Organic Pollutant toxicity as a cause of obesity. We also examine the ways by which rapid weight loss can sometimes be detrimental for someone with a high toxic load. Finally, we look at safe and effective means of ridding the body of these chemicals. ---------------------------------------------------------- Find me: Website: https://www.eonutrition.co.uk/ Facebook: https://www.facebook.com/eonutrition Twitter: https://twitter.com/EO_Nutrition IG: https://www.instagram.com/eonutrition/ Check out my new FB group here: https://www.facebook.com/groups/thiamineprotocols For a clean form of thiamine TTFD with no fillers, look to Objective Nutrients https://www.objectivenutrients.com/ Looking for guidance on using high dose thiamine? Download my protocols here: https://thiamineprotocols.com/ DISCLAIMER: Elliot is not a medical professional and the information in this video is provided for general informational and educational purposes only and is not a substitute for professional advice. Always consult with your primary healthcare provider for medical advice. #obesity #obesityepidemic #fatloss #fat #obese #weightloss #weight #toxicity #toxic

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(https://isappscience.org/wp-content/uploads/2025/07/Greiner-cover.png) This episode features Dr. Thomas Greiner PhD from the University of Gothenburg (Sweden), speaking about the various functions of GLP-1 in the gut, and the role of gut microbes in GLP-1 production, with ultimate effects on host health. He noted that GLP-1 is produced by enteroendocrine cells called L-cells, both in the small intestine and the colon. These cells respond to nutrients and microbially-produced short-chain fatty acids, but responses differ between the small intestine and colon, leading Dr. Greiner to investigate the different functions of GLP-1 at these two sites. Using germ-free mice and other models, Dr. Greiner has developed a hypothesis that the function of GLP-1 in the small intestine is to improve insulin secretion postprandially, whereas the functions of GLP-1 in the colon are to allow for increased energy intake (in a situation of energy deficiency), dampen inflammation, and protect local tissues. He and his colleagues are taking two different approaches in aiming to improve metabolic health in humans: finding inhibitors of bacterial enzymes to decrease production of a harmful molecule produced by bacteria; and a probiotic approach of administering butyrate-producing bacteria. With the latter approach, the sensitivity of the bacteria to oxygen is a problem to overcome, but their group has evolved a bacterial strain to tolerate some oxygen, with the idea of testing it as a probiotic. Episode abbreviations and links: • Paper exploring the role of the gut microbiota in GLP-1 signaling: GLP-1R signaling modulates colonic energy metabolism, goblet cell number and survival in the absence of gut microbiota (https://www.sciencedirect.com/science/article/pii/S2212877824000553?via%3Dihub) • Study on the functions of GLP-1 in the colon: Microbial Modulation of Energy Availability in the Colon Regulates Intestinal Transit (https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(13)00365-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS193131281300365X%3Fshowall%3Dtrue) • Bäckhed Lab Instagram account: @backhed_lab (https://www.instagram.com/backhed_lab?igsh=MWdpdmlndDAxOWFjag==) About Dr. Thomas Greiner PhD: Thomas Greiner is a medical scientist at the Wallenberg Laboratory, University of Gothenburg, with over 15 years of experience in functional genetics and metabolic research. His work focuses on the intricate interplay between gut microbiota, intestinal hormones such as GLP-1, and host metabolism. He has explored how microbial and hormonal signals influence energy balance, intestinal function, and the development of metabolic diseases. His research primarily uses molecular approaches in mouse models to investigate the role of microbial signals in metabolic disease and to uncover new functions of gut hormones in regulating intestinal physiology. Sign up (https://isappscience.org/for-scientists/news/isapp-newsletters/) for our monthly newsletter Follow us (https://isappscience.org/contact/) on LinkedIn, Bluesky, X, Facebook, Instagram, Threads The post Unraveling the functions of GLP-1 in the gut, with Dr. Thomas Greiner PhD (https://isappscience.org/episode-65-unraveling-the-functions-of-glp-1-in-the-gut/) appeared first on International Scientific Association for Probiotics and Prebiotics (ISAPP) (https://isappscience.org) .

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The popular Australian TV and radio personality Chrissie Swan is one of the latest celebrities to lose weight and gain health by adopting the Keto diet. The popular Australian TV and radio personality, Chrissie Swan, struggled with weight loss for years. The television host and author developed a penchant for weight loss issues, which inspired many to follow her journey. However, the popular host and mother of two only found a sustainable way to lose weight and keep it off when she made Keto part of her general health and wellness regimen.

Chrissie Swan’s Journey to Keto

Chrissie Swan is a popular television personality and radio host in Australia. She had tried ‘every diet and weight-loss program’ but never made any headway. She found it hard to stick to strict meal plans, and difficult to eat in a way that supported good health. Then, after learning about the Keto diet (where your body burns fat, not carbs, for energy), everything changed. She decided to try Keto: The transformation was extraordinary.

But after just a few weeks on the Keto diet, Chrissie Swan could start to see a marked difference. It wasn’t only weight loss: she started feeling better and her focus improved, she was satisfied after eating and no longer wanted to keep snacking. Her blood pressure dropped. And she’s never been hungry. By fueling her body with healthy fats and protein, and cutting out carbs and sugar, Chrissie Swan found a way of eating that she could easily maintain and lose weight for life.

Chrissie Swan’s Keto Diet Success

Meal planning is another secret to sticking to the Keto diet. Chrissie plans and prepares everything in advance, including her meals and snacks. And she has success with this diet because she finds delicious recipes that are keto-friendly and tasty. They help to stop her cravings and avoid falling back into her unhealthy habits. Chrissie also credits her weight loss success to eating whole, nutrient-dense food like avocados, nuts, seeds and loads of vegetables. These are good foods that nourish the body and the brain.

Chrissie currently regularly exercises and stays active with some form of Keto diet to maintain her weight loss. These options keep her living life to the full and keeping her body healthy. ‘I go for a walk, go to the gym, do yoga. Make it something that’s about enjoyment. Doing something that you enjoy getting your body moving in ways that feel good to you. That’s super important because it is such a part of life.’

Chrissie Swan’s Tips for Keto Success

If you’re intrigued enough to want to try Keto yourself, writer Chrissie Swan shares some of the principles that helped her make the diet sustainable – and actually enjoyable. First of all, she stresses the importance of researching the Keto diet and the why behind it. Become aware of all the ins and outs of the Way of Eating. Read about ketosis and how fats and carbs are metabolised. This will help you to consciously build a sustainable eating plan for your own body from the ground up.

Chrissie then draws attention to how listening to your body, noticing how certain foods make you feel, can help you to retreat from food rules and follow your innate wisdom for what your body needs. It also helps you nurture your appetite so that hunger cues and cravings can be your instinctive guide. Tune in and you will become proficient at feeling your optimum appetite and can restrict or override when needed. As I’ve mentioned, everyone’s optimal food choices are different; each of us has a unique set of needs. So, reimagine your approach to nourishing your body – think about your personal pantry, then stock and adjust your diet accordingly so that your food choices support your goals for health, vitality and wellness.

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This workout uses a combination of cardio and strength exercises to help you burn those calories. Although I’m not a strong believer in losing local fat depots, this workout will help you to decrease your overall fat level and tone your belly. This cardio workout to lose belly fat burns calories during the workout, but will also give your metabolism a boost. This helps burning calories and fat even hours after performing the workout. Consisting of two sets that are repeated twice, this workout takes 4 x 5 minutes. After each set there will be a short water break. Be sure to go at your own pace! FitnessType is also on Facebook: https://www.facebook.com/fitnesstype Enjoy! Marischa

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