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Many people who are overweight or obese are turning to drugs used to manage diabetes for help dropping those extra pounds. Doctors say there are things to know before you consider taking this route.
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Semaglutide is a drug that has been making waves in the weight loss world due to its effectiveness in helping individuals shed excess pounds. But how exactly does semaglutide work for weight loss? Understanding the science behind this medication is crucial for anyone considering it as a treatment option. In this article, we will delve into the mechanisms of semaglutide and explore how it can help you achieve your weight loss goals.
How Does Semaglutide Work?
Semaglutide belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists. These drugs mimic the effects of a naturally occurring hormone in the body called GLP-1. GLP-1 is released from the gut in response to food intake and helps regulate blood sugar levels by stimulating the release of insulin from the pancreas. In addition to its effects on blood sugar, GLP-1 also plays a role in regulating appetite and food intake.
When semaglutide is administered, it activates the GLP-1 receptors in the body, leading to a cascade of physiological effects. One of the primary ways that semaglutide helps with weight loss is by reducing appetite and promoting a feeling of fullness. This is achieved through the modulation of brain circuits that control hunger and satiety, ultimately leading to a decrease in food intake.
Another key mechanism by which semaglutide promotes weight loss is by slowing down gastric emptying. This means that food stays in the stomach for a longer period of time, which can help individuals feel fuller for longer and reduce overall calorie intake. By slowing the rate at which food is digested and absorbed, semaglutide can help regulate blood sugar levels and prevent spikes in insulin that can lead to weight gain.
The Role of Semaglutide in Metabolism
Aside from its effects on appetite and food intake, semaglutide also has a direct impact on metabolism. Studies have shown that semaglutide can increase the body’s energy expenditure, or the number of calories burned at rest. This is achieved through the activation of brown fat, a type of fat tissue that generates heat by burning calories. By increasing energy expenditure, semaglutide can help individuals achieve a negative energy balance, which is essential for weight loss.
In addition to its effects on energy expenditure, semaglutide can also improve insulin sensitivity and glucose metabolism. Insulin sensitivity refers to how effectively the body responds to insulin, the hormone responsible for regulating blood sugar levels. By enhancing insulin sensitivity, semaglutide can help the body better utilize glucose for energy production, which can prevent the excess storage of fat and promote weight loss.
Overall, the multifaceted effects of semaglutide on appetite, metabolism, and insulin sensitivity make it a powerful tool for weight loss. By targeting key pathways involved in weight regulation, semaglutide offers a comprehensive approach to managing obesity and achieving long-term success in maintaining a healthy weight.
Considerations and Potential Side Effects
While semaglutide has shown great promise as a weight loss treatment, it is important to consider the potential side effects associated with this medication. Common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation. These side effects are typically mild to moderate in nature and tend to improve over time as the body adjusts to the medication.
In rare cases, semaglutide can also lead to more serious side effects such as pancreatitis or thyroid tumors. It is essential to discuss these risks with your healthcare provider before starting treatment with semaglutide. Additionally, semaglutide is not recommended for individuals with a history of pancreatitis or thyroid cancer, as it may exacerbate these conditions.
As with any medication, it is crucial to use semaglutide under the supervision of a healthcare provider to ensure safe and effective treatment. Your doctor can help determine if semaglutide is the right option for you based on your individual health status and weight loss goals. By understanding how semaglutide works and its potential benefits and risks, you can make an informed decision about incorporating this medication into your weight loss journey.
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How do you work out your calories to lose fat?! Sounds simple, right? That's because it is very straightforward! Even the equation I give you to work out your maintenance calorie levels is very easy to use. I forgot to mention in the video, with the equation, you can reduce your calories by 10% after a few weeks of maintenance. Or you can just start in a 10% deficit. Your goal should be to maintain/build muscle while losing fat, that's why we start so modest. Remember to reevaluate your calorie levels every 2-4 weeks to see if you need to reduce calorie levels or keep them the same. --------------------------------------------------------------------------------------------------------------------- I hope you enjoyed this video. Be sure to smash that thumbs up button! Hit that subscribe button and turn on the bell notification to be updated whenever I post a video. Until the next video, keep pushing those limits! --------------------------------------------------------------------------------------------------------------------------- Follow me: *Instagram: www.instagram.com/adamscottfit *Facebook: www.facebook.com/adamscottfit If you want me to help you with your training or nutrition, go visit www.adamscottfit.com for tailor-made plans. **DISCLAIMER** The information in this video is merely the opinion of me based on my research and studies. The research and information covered in this video is open to public domain for discussion and in no way breaches or breaks the boundaries of the law in the United Kingdom where I live. I am not a doctor, nor do I claim to have any formal medical background. I am not liable, either expressly or in an implied manner, nor claim any responsibility for any emotional or physical problems that may occur directly or indirectly from watching this video! #caloriecalculator #losefat #calories
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Dr. G and Bri break down all there is to know about weight loss meds, from what to expect during a consultation to why a plastic surgery office is the place to go for them. They also share their own personal experiences with these meds: the benefits, the side effects, and how their cravings have done a total 180. Dr. G & Bri cover: - The differences between semaglutide and tirzepatide - The headache of medication shortages - Risks of unregulated compounding pharmacies - Why medical oversight makes all the difference - Bonus perks of weight loss meds (beyond the scale) - What happens if you overindulge while on these meds - The importance of sourcing meds from legit providers - Why lab work is a must before you start - Whether you need to stay on the meds after reaching your goal - Tips for managing loose skin after weight loss Trending stories: Forbes, Plastic Surgeons Predict The Top Aesthetic Procedures For 2025 https://www.forbes.com/sites/jessicaourisman/2024/12/16/plastic-surgeons-predict-the-top-aesthetic-procedures-for-2025/ Yahoo, "I Went To The Wrong Guy To Put My Face Back Together": 7 Male Celebrities Who Opened Up About Their Cosmetic Surgery Regrets https://www.yahoo.com/entertainment/7-famous-men-regretted-cosmetic-113103303.html Weight loss-related articles: Daily Mail, Demand for Ozempic and Wegovy will soar in New Year - as people keen to lose weight say they'll enjoy one final festive feast before starting obesity drugs https://www.dailymail.co.uk/femail/article-14189787/Ozempic-Wegovy-sales-soar-New-Year-Christmas-dinner.html Daily Mail, Sports Illustrated Swimsuit model Brooks Nader admits she 'really liked' Ozempic https://www.dailymail.co.uk/femail/article-14186091/sports-illustrated-model-brooks-nader-really-liked-ozempic.html ScienceNews, The benefits of Ozempic and its kin may extend far beyond weight loss https://www.sciencenews.org/article/benefits-ozempic-weight-loss-glp1 Links Learn more about our prescription weight loss program https://restoresdplasticsurgery.com/procedures/prescription-weight-loss-program/ Hosted by San Diego plastic surgeon Dr. Kat Gallus and her trusty sidekick scrub tech Bri, this is a podcast for women who have always wished they had a slightly snarky, super experienced, and totally unintimidating female plastic surgeon as their BFF to help sort through the what, where, and why of the available cosmetic treatment options. All the B’s covers aesthetics and plastic surgery through the lens of trending pop culture stories and celebrity gossip. Who are the B’s? The all-female team working closely with Dr. Gallus every day at Restore SD Plastic Surgery in La Jolla, California. Getting plastic surgery is a big deal, and they go the extra mile to make sure you feel super comfortable and know exactly what's going on. To learn more about the practice or ask a question, go to https://restoresdplasticsurgery.com/ Follow Dr. Gallus and the team on Instagram @restoresdplasticsurgery (https://www.instagram.com/restoresdplasticsurgery/) Watch Dr. Gallus and Bri on YouTube @restoresdplasticsurgery7487 (https://www.youtube.com/channel/UChuFFMd4bauIfHr1wgIRTQA) Got a question for us? Send us a message or leave us a voicemail at https://itsthebs.com/ Co-hosts: Dr. Katerina Gallus & Brianna Lempe Producer: Eva Sheie Assistant Producers: Mary Ellen Clarkson & Hannah Burkhart Engineering: Aron Devereaux Theme music: Rear View, Nbhd Nick Cover Art: Dan Childs All the B’s is a production of The Axis: https://www.theaxis.io/ Contents of this video: 00:00 - 2024 wrapped 01:35 - Lindsay Lohan’s whole new face 02:40 - Regenerative aesthetics 08:10 - The early intervention facelift 11:20 - Post weight loss body procedures 12:20 - Male celebrities with cosmetic surgery regrets 25:05 - Demand for Ozempic and Wegovy in 2025 27:30 - Brooks Nader admits she “really liked” Ozempic 30:45 - Why was there so much controversy with semaglutide? 33:30 - Semaglutide & tirzepatide shortages 37:00 - Why is lab work important for weight loss meds? 38:40 - Benefits of semaglutide 40:15 - Our experiences on weight loss meds 52:40 - Our patients’ weight loss results 53:40 - Maintenance on weight loss medications 56:10 - Staying active on weight loss meds 57:48 - Getting rid of loose skin after weight loss 59:20 - Getting to your goal weight to be eligible for surgery 1:01:10 - Scheduling your weight loss consultation 1:03:40 - Does the skinny shot hurt? 1:04:16 - The most common GLP-1 injection sites 1:04:40 - Takeaways
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