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GLP-1 is secreted by intestinal cells in response to glucose ingestion and acts on the vagus nerve and hypothalamus to induce satiety. Subscribe to Nourishable at https://www.youtube.com/c/Nourishable This video is part 6 of the Neurobiology of Food Intake module within a lecture series on the nutrition science of macronutrients. Neurobiology of Food Intake Lecture playlist: https://youtube.com/playlist?list=PLK6oS2Cd-6PE_gAHJP2eQaP01IrvL7OQJ Macronutrients Lecture playlist: https://youtube.com/playlist?list=PLK6oS2Cd-6PGI0ALaBRBb10s51Z0NEmvw Follow Nourishable on twitter, facebook and instagram to stay up to date on all things nutrition. https://twitter.com/nourishable fb.me/nourishable.tv https://www.instagram.com/nourishable/ Lecture Development, Hosting & Post-Production by Lara Hyde, PhD http://www.nourishable.tv Video Production by Robbie Hyde https://www.youtube.com/user/chedderchowder Opening Motion Graphics by Jay Purugganan https://www.c9studio.com/WP/ The information in this video is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images and information, contained on or available through this video is for general information purposes only. References Klockars, A. et al. Hypothalamic Integration of the Endocrine Signaling Related to Food Intake. Curr. Topics Behav. Neurosci. (2019) 43:239-270 Images Figures created with BioRender Glucagon-like peptide 1, or GLP-1, is a hormone secrets by the L cells in the intestine in response to glucose ingestion in proportion to consumed calories. GLP-1 stimulates insulin secretion from the pancreas to prepare the body for high blood glucose levels - this makes it an incretin because it increases insulin. Further, GLP-1 inhibits glucagon. GLP-1 binds to chemoreceptors on the vagus nerve to activate the vagus to send afferent signals to stimulate the nucleus tractus solitarius in the hindbrain to stimulate satiety. GLP slows gastric emptying which keeps the GI tract stretched and distended for longer - this activates the stretch-sensitive mechanoreceptors on the vagus to additionally stimulate the NTS. GLP-1 crosses the blood-brain-barrier of the hypothalamus to activate the POMC neurons in the arcuate nucleus. POMC neuron stimulation causes release of the neurotransmitter alpha MSH which stimulates the paraventricular hypothalamus to induce satiety. GLP-1 also inhibits the orexigenic AgRP neurons. GLP-1 is an anorexigenic, satiety-inducing hormone.

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Why Does Average Weight Loss on Wegovy Happen? In this informative video, we’ll break down the science behind Wegovy, a popular medication for weight loss. We’ll discuss its active ingredient, semaglutide, and how it mimics a natural hormone in the body that regulates appetite. You’ll learn about how this medication works to help reduce cravings and the desire to eat, leading to lower food consumption. We’ll also cover the effects of semaglutide on digestion and how this contributes to prolonged feelings of fullness after meals. Furthermore, we’ll share findings from clinical studies that highlight the average weight loss experienced by patients using Wegovy over different time frames. You’ll discover how varying doses of semaglutide can influence weight loss results and the additional health benefits that come with weight reduction, including improvements in blood pressure and cholesterol levels. If you’re exploring effective solutions for weight management and want to understand how Wegovy can fit into your journey, this video is for you. Join us for a detailed discussion on this medication and its role in tackling obesity and related health concerns. Don't forget to subscribe to our channel for more helpful information on health and wellness! ⬇️ Subscribe to our channel for more valuable insights. 🔗Subscribe: https://www.youtube.com/@ObesityFightersClub/?sub_confirmation=1 #Wegovy #WeightLoss #Semaglutide #ObesityManagement #HealthyLiving #WeightLossJourney #AppetiteControl #WeightLossMedication #HealthBenefits #WeightLossResults #Cholesterol #BloodPressure #MetabolicHealth #Nutrition #Wellness About Us: Welcome to Obesity Fighters Club! Our channel is dedicated to helping you achieve your weight loss goals and embrace a healthier lifestyle. We cover a variety of topics, including effective weight loss tips, healthy eating habits, and fitness motivation tailored for all levels. Whether you're seeking fat-burning workouts or meal planning strategies for sustainable weight loss, we’ve got you covered.The content provided is for general, informational, and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

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MC Shares the surprise that insurance companies stop their coverage of these medications once a person reaches a BMI of 30. What arbitrary craziness is this? Shouldn't the doctor make a decision on what is medically appropriate, not the insurance company? Why are insurance companies practicing medicine? Please note my disclaimer. The ideas and information shared on my channel are not supported by my employer or endorsed by any company. I do not have any affiliates with any of the referrals listed below. Everything on my channel is shared for education and entertainment. You can contact me at - [email protected] or www.marycatherinegeorge.com

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From Shark Tank to Your Home: The Truth About Diet Gummies

In recent years, there has been a surge in the popularity of diet gummies, thanks in part to the exposure they received on popular television shows like Shark Tank. These gummies claim to help individuals lose weight by suppressing their appetite, increasing their metabolism, and promoting fat burning. But are these claims too good to be true? In this article, we will explore the truth behind diet gummies, their effectiveness, and potential risks.

The Ingredients of Diet Gummies

One of the key ingredients in diet gummies is usually a substance called hydroxycitric acid (HCA), which is derived from the fruit of the Garcinia Cambogia plant. HCA is believed to block an enzyme called citrate lyase, which the body uses to make fat. By inhibiting this enzyme, HCA may help to reduce fat storage and control appetite. However, studies on the effectiveness of HCA for weight loss have been mixed, with some showing positive results and others showing no significant impact.

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Another common ingredient in diet gummies is green coffee bean extract, which is believed to help with weight loss by reducing the absorption of carbohydrates and increasing fat burning. Green coffee bean extract contains chlorogenic acid, which is thought to have antioxidant and metabolism-boosting properties. While some studies have shown promising results for green coffee bean extract in aiding weight loss, more research is needed to confirm its effectiveness.

Some diet gummies also contain fiber, such as glucomannan, which is a water-soluble dietary fiber derived from the konjac plant. Fiber is known to promote feelings of fullness and reduce calorie intake, which can aid in weight loss. However, the effectiveness of fiber in the form of diet gummies is debatable, as the amount of fiber in each gummy may not be enough to have a significant impact on weight loss.

Potential Risks of Diet Gummies

While diet gummies may seem like a convenient and tasty way to help with weight loss, they come with potential risks and side effects. Some users may experience digestive issues such as bloating, gas, and diarrhea, especially if the gummies contain high amounts of fiber or sugar alcohols. Additionally, the long-term effects of regularly consuming diet gummies are not well-studied, so it is unclear how they may impact overall health over time.

Another risk of diet gummies is the potential for overconsumption. Since gummies are often seen as a harmless treat, individuals may be tempted to consume more than the recommended dosage in hopes of speeding up weight loss. This can lead to an excessive intake of certain ingredients, which may cause negative effects on health.

It is also important to note that diet gummies are not a magical solution for weight loss. While they may offer some benefits in terms of appetite control and metabolism, they should not be relied upon as the sole method for losing weight. A healthy diet, regular exercise, and lifestyle changes are still the most effective and sustainable ways to achieve and maintain a healthy weight.

Conclusion

In conclusion, diet gummies may offer some benefits in aiding weight loss, but their effectiveness and safety are not guaranteed. It is important to carefully read the label, follow the recommended dosage, and consult with a healthcare provider before incorporating diet gummies into your weight loss plan. Remember that there is no substitute for a balanced diet and active lifestyle when it comes to achieving long-term weight loss and overall health.

Whether you decide to try diet gummies or not, it is crucial to approach weight loss with caution and prioritize your health above all else.

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Let's talk about healthy weight loss! There are many synthetic (9 total) pharmaceutical injections that mimic the GLP1 hormone (that naturally occurs in your body) and regulate hunger, digestion, satiation, and more. NOW there is an all-natural version with no short or long-term side effects (because it's not synthetic). It launches this October 9th, and I can't wait to share the ingredients, studies, and results!

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