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How Testosterone Affects Fat Loss: Real Science of Low-T | Thomas DeLauer: I'm sick of the lack of legitimacy behind testosterone, so let's clear some of this up. I work with a lot of men that are battling Low-T by helping them with their lifestyle at http://www.ThomasDeLauer.com As men age, their testosterone levels decline. This is exacerbated by an increase in SHBG (sex-hormone binding globulin), which binds to testosterone and thus reduces the amount of free testosterone in the body. Low testosterone levels have been linked to obesity and many other health problems, including fatigue, memory problems and reduced muscle and bone mass. So what is the impact of testosterone on body fat? Testosterone and energy - low levels of testosterone are linked with low energy levels. Regaining regular testosterone levels can increase energy and lead to weight loss. Studies have found that testosterone supplementation reduces total body fat percentages. Obesity is often correlated with low testosterone levels in men. Just as testosterone therapy is associated with decreased obesity, losing weight is associated with increased testosterone levels. An article published in 2014 in the journal of Current Opinion in Endocrinology, Diabetes and Obesity looked at the existing data regarding testosterone therapy in overweight and obese men with testosterone deficiency (hypogonadism). -Many weight loss supplements have dangerous side effects or are ineffective -Looked at weight loss, BMI, waist circumference and body composition -Evaluated long-term testosterone therapy -About 40% of obese nondiabetic men and 50% of obese diabetic men over 45 have low levels of free testosterone -Many studies have found that testosterone therapy in obese men is correlated with increased lean body mass, weight loss, decreased BMI and reduced waist circumference. -Weight loss is significant and sustained with long-term testosterone therapy Testosterone plays a part in protein, fat and carbohydrate metabolism. -Testosterone is involved with mitochondrial function and thus energy production and utilization -This interference with energy production is likely why those with low testosterone levels experience a lack of energy -Testosterone therapy has been found to increase lipid oxidation and normalize glucose use in the body. It was found to increase energy and motivation. Weight gain is associated with an 88% increase in body fat and a 12% increase in lean body mass (LBM) and weight loss with a 72% decrease in body fat and a 28% decrease in LBM. -With testosterone therapy LBM has been shown to increase. -Increased LBM means increased energy expenditure at rest -Testosterone therapy is also associated with improved cardiometabolic function Testosterone deficiency is linked with a decrease in energy metabolism from fat and an increase in energy metabolism from glucose. -Testosterone therapy has been shown to increase lipid metabolism Safety? Safety is the main concern with testosterone replacement therapy. Possible risks discussed in literature include: -Increased risk of prostate and breast cancer -Liver toxicity and tumors -Sleep apnea exacerbation -Testicular infertility and atrophy It is necessary to talk with your doctor before starting testosterone therapy. Summary: If you are a male struggling to lose weight, testosterone therapy is a promising treatment to help with not only weight loss but body composition, energy levels and overall health. References: 1. Dose-dependent effects of testosterone on regional adipose tissue distribution… http://press.endocrine.org/doi/10.1210/jc.2003-031492?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed 2. Testosterone and weight loss: the evidence https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154787/ 3. Effects of testosterone treatment on body fat and lean mass in obese men on a hypocaloric diet… https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054608/ 4. The benefits and risks of testosterone replacement therapy: a review https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2701485/

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If you have struggled with weight loss in the past, you may be interested in participating in a Semaglutide weight loss trial. Semaglutide is a medication that has shown promising results in helping individuals achieve their weight loss goals. Clinical trials are essential in testing the effectiveness and safety of new medications, and participating in one can not only benefit you but also contribute to scientific research.

What is Semaglutide?

Semaglutide is a medication that was originally developed to treat type 2 diabetes. However, recent studies have shown that it can also be effective in promoting weight loss. Semaglutide works by mimicking the function of a hormone called glucagon-like peptide-1 (GLP-1), which helps regulate insulin and blood sugar levels. By increasing feelings of fullness and reducing appetite, Semaglutide can assist individuals in making healthier food choices and consuming fewer calories.

One of the main advantages of Semaglutide is that it can be administered via injection, making it a convenient option for individuals looking to manage their weight. Clinical trials have demonstrated that Semaglutide can lead to significant weight loss when combined with a healthy diet and regular exercise. If you have struggled to lose weight through diet and exercise alone, participating in a Semaglutide weight loss trial may be a viable option for you.





How to Participate

If you are interested in participating in a Semaglutide weight loss trial, the first step is to speak with your healthcare provider. They can provide you with more information about the trial and help you determine if it is the right choice for you. Your healthcare provider will evaluate your current health status and medical history to ensure that you meet the eligibility criteria for the trial.

Once you have been deemed eligible to participate in the trial, you will be required to undergo a series of assessments to establish a baseline for comparison. These assessments may include measurements of your weight, height, body mass index (BMI), blood pressure, and blood tests to evaluate your overall health. Additionally, you may be asked to keep a food diary and track your physical activity to monitor your progress throughout the trial.

Benefits of Participating

Participating in a Semaglutide weight loss trial can offer numerous benefits beyond just weight loss. You will have access to a team of healthcare professionals who can provide guidance and support as you work towards your weight loss goals. Additionally, you will be closely monitored throughout the trial to ensure your safety and well-being.

By participating in a clinical trial, you will also be contributing to the advancement of medical research. Your participation may help researchers better understand the effects of Semaglutide on weight loss and potentially lead to the development of more effective treatments for obesity and related health conditions. Overall, participating in a Semaglutide weight loss trial can be a rewarding experience that not only benefits you but also the scientific community as a whole.

Considerations Before Participating

Before deciding to participate in a Semaglutide weight loss trial, it is important to carefully consider the potential risks and benefits. While Semaglutide has shown promising results in clinical trials, it may not be suitable for everyone. You should discuss any concerns or questions with your healthcare provider before enrolling in the trial.

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It is also important to understand that participating in a clinical trial requires a commitment of time and effort. You may be required to attend regular appointments, adhere to a specific diet and exercise plan, and report any side effects or changes in your health status. It is essential to follow the trial protocol closely to ensure accurate results and maximize the potential benefits of the medication.

Conclusion

Overall, participating in a Semaglutide weight loss trial can be a valuable opportunity for individuals looking to achieve their weight loss goals. By working closely with healthcare professionals and contributing to scientific research, you can take a proactive step towards improving your health and well-being. If you are interested in participating in a Semaglutide weight loss trial, speak with your healthcare provider to learn more about this exciting opportunity.

Remember to carefully consider the potential risks and benefits before enrolling in a trial and ensure that you meet the eligibility criteria. By participating in a clinical trial, you can not only benefit yourself but also contribute to the development of innovative treatments for obesity and related health conditions.

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