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View show notes here: https://bit.ly/4exzjNe Become a member to receive exclusive content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ In this “Ask Me Anything” (AMA) episode, Peter dives back into the increasingly popular topic of GLP-1 agonists, such as Ozempic & Mounjaro, which have garnered widespread attention for their ability to promote weight loss. Peter covers the latest findings in this rapidly evolving landscape, including new insights into their long-term efficacy, side effects, & what happens when the drug is discontinued. Peter also explores their impact on body composition & how resistance training interacts with these treatments. Additionally, he compares different GLP-1 receptor agonists & discusses promising new drugs in the pipeline. Finally, Peter addresses questions about the role of compounding pharmacies in the GLP-1 agonist market, compares oral vs. injectable options, & provides key considerations for anyone deciding whether to use a GLP-1 agonist for weight loss. We discuss: 00:09 - The rapidly evolving landscape of GLP-1 agonists 5:14 - The mechanism of GLP-1 agonists, origin as diabetes treatments, & how they evolved into weight-loss drugs 09:08 - Overview of new data & open questions related to the benefits & risks of GLP-1 agonists 16:19 - New insights into the long-term safety of GLP-1 agonists & side effects In the full episode, we also discuss: The long-term efficacy of GLP-1 agonists, financial barriers, & more; The mechanisms behind GLP-1 agonists' ability to promote weight loss; New data on body weight changes after discontinuing the drug; Effects of GLP-1 agonists on lean mass & body composition, & the role of protein & resistance training in preserving muscle; Semaglutide vs. tirzepatide; How compounding pharmacies affect availability of GLP-1 drugs & the available formulations; How oral formulations of GLP-1 drugs compare to injectable formulations; How sublingual (under tongue) formulations of GLP-1 drugs compare to injectable formulations; Guidance for using compounding pharmacies to purchase GLP-1 agonists; Data on retatrutide—a promising new triple receptor agonist in the pipeline; Can GLP-1 agonists be beneficial for sleep apnea & immune function?; Potential neuroprotective benefits of GLP-1 agonists: impact on dementia risk; Exploring why GLP-1 agonists may reduce the risk of cancer, kidney disease, & cardiovascular disease; How GLP-1 agonists might boost fertility in women; Early indications that GLP-1 agonists may help treat substance abuse disorders; Potential health risks of GLP-1 agonists: addressing thyroid cancer concerns & the unknowns due to lack of data; Examining the potential link between GLP-1 agonists & increased depression or suicidal ideation; Major remaining questions: the effects of cyclic use, rebound appetite, impact on adolescents' development, & more; Key considerations when deciding whether to use a GLP-1 agonist for weight loss; -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, & all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, & much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan & simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only & does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information & the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, & they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures & the companies I invest in or advise, please visit my website where I keep an up-to-date & active list of such companies. For a full list of our registered & unregistered trademarks, trade names, & service marks, please review our Terms of Use: https://peterattiamd.com/terms-of-use/

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👍 Order your own functional medicine lab kits in my labshop: https://labs.rupahealth.com/store/storefront_6G8ar7P GLP-1 Medications: Side Effects & Weight Loss. Healthy and real weight loss can be difficult to achieve and the need for weight loss solutions is high, thus the creation of the GLP-1 (glp 1) agonists, which include Wegovy and Ozempic, among others. Wegovy weight loss and ozempic weight loss, as well as Trulicity or Saxenda, can be significant and can include healthy weight loss, but Wegovy side effects can be a problem as well (and the others have similar side effects). How do glp 1 agonists works? This video includes how glp 1 agonists work, glp 1 agonists side effects, costs, Wegovy reviews and Ozempic reviews, and more, to help you determine what tools are right for you on your healthy weight loss journey. Pendulum Akkermansia 20% off first order discount code DRMEYER, https://pendulumlife.com/ or my online supplement dispensary https://us.fullscript.com/o/catalog?query=%22pendulum%22 💩Trust Your Gut Course at a new deeply discounted price!!!! Check out the link below: https://cutt.ly/zNKDX4d For the PDF please join my email list here: https://www.drshelleymeyer.com/ Subscribers (already subscribed) will get the pdf automatically in their emails inbox. Would you like to learn how to fix your imbalanced gut bacteria, intestinal methane overgrowth or small intestinal bacterial overgrowth (SIBO)? Check out my ebook "The Ultimate SIBO Guide". This guide will walk you through How to recognize or diagnose IMO or SIBO How to eat when you have IMO or SIBO How to treat IMO or SIBO What supplements can help your gut recover And so much more! You will love this informative guide, it is a lifesaver when it comes to healing your gut! https://amzn.to/41KylpN ❤SOCIAL MEDIA LINKS: Instagram: @drshelleymeyer Check out my blog at https://www.drshelleymeyer.com/ Facebook: @drshelleymeyer 📲Check out my practice at highlandshealthwellness.com or solve your gut problems with my Trust your Gut course https://cutt.ly/zNKDX4d How to eat when you have IMO or SIBO How to treat IMO or SIBO What supplements can help your gut recover And so much more! You will love this informative guide, it is a lifesaver when it comes to healing your gut! https://amzn.to/46SKoFc *Disclosure: I only recommend products I would use myself and all opinions expressed here are our own. This post may contain affiliate links that at no additional cost to you, I may earn a small commission.

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00:00 - The Hidden Risks of GLP-1 Weight Loss Drugs: Muscle Loss and Fitness 02:58 - The Truth About GLP-1s: Separating Fact from Fiction 1. The Hidden Risks of GLP-1 Weight Loss Drugs: Muscle Loss and Fitness In this video, we explore the recent findings on GLP-1 drugs like semaglutide and tirzepatide. While these medications can help with weight loss, new research reveals they may lead to significant muscle loss and fail to improve fitness levels. Join us as we discuss: - The impact of GLP-1 drugs on muscle health - The importance of cardiorespiratory fitness (CRF) - Recommendations for patients considering these medications - The need for further research in this area Stay informed about your health and the medications you take! 2. The Truth About GLP-1s: Separating Fact from Fiction Dr. Scott Masey, a national weight loss doctor, joins Bloom Health Club to discuss the benefits and uses of GLP-1 drugs. Originally developed for diabetes, these medications are now being used to help people manage weight and improve their overall health. Dr. Masey shares his expertise on how GLP-1s can reduce cravings, support addiction recovery, and even protect the brain. He also answers viewer questions about staying on a maintenance dose and building lasting results. Learn more about the potential of GLP-1s and how they can change your life. Key points: - What are GLP-1s and how do they work? - Benefits of GLP-1s beyond weight loss - How to combine GLP-1s with nutrition and exercise for optimal results - Potential uses of GLP-1s in treating conditions like Alzheimer's - Tips for staying on a maintenance dose and achieving lasting results Visit National Weight Loss Centers for more information.

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