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GLP-1 medications like Ozempic and Wegovy are revolutionizing obesity treatment, but a new University of Virginia study reveals a potential downside: They don’t significantly boost cardiorespiratory fitness (CRF)—a critical predictor of long-term health and longevity. 🔬 Key Findings: ✔️ GLP-1s cut fat but also muscle—up to 40% of weight loss is lean mass. ✔️ No clear improvement in VO₂ max (a key measure of heart/lung fitness). ✔️ Low CRF = higher mortality risk, even if weight drops. 💡 The Solution? Exercise & protein intake may help preserve muscle. New drugs in development could offset muscle loss. Doctors urged to screen patients for malnutrition risks before prescribing. #Ozempic #WeightLoss #Health #Fitness #MedicalResearch 💬 Would you take a GLP-1 drug knowing it might not improve fitness? 🔔 Subscribe for more science-backed health insights! ⚕️ Why This Matters: CRF (cardiorespiratory fitness) is a stronger predictor of lifespan than BMI. Muscle loss on GLP-1s could increase frailty and metabolic risks. Combining meds with exercise might be the missing key to full health benefits. Study Published in: The Journal of Clinical Endocrinology & Metabolism DOI: 10.1210/clinem/dgaf335

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Semaglutide is a medication that has gained popularity in recent years for its potential to aid in weight loss programs. As a glucagon-like peptide-1 (GLP-1) receptor agonist, semaglutide works by increasing feelings of fullness, slowing stomach emptying, and reducing appetite. This makes it an attractive option for individuals struggling to lose weight through diet and exercise alone. In addition to its use in managing type 2 diabetes, semaglutide has been approved by the FDA for chronic weight management in adults with a body mass index (BMI) of 27 kg/m2 or higher who have at least one weight-related condition.

Dosage Chart

When using semaglutide for weight loss, it is important to follow a prescribed dosage chart to ensure safe and effective results. The recommended starting dose of semaglutide for weight management is 0.25 mg once weekly for the first 4 weeks. This dose can then be increased to 0.5 mg once weekly, and further increased to 1 mg once weekly, if necessary. It is important to consult with a healthcare provider before adjusting the dosage to determine the best plan for individual weight loss goals and health needs.

Individuals using semaglutide for weight loss should administer the medication by subcutaneous injection once weekly on the same day each week, at any time of day, with or without food. It is important to rotate injection sites to minimize the risk of injection site reactions. It is also recommended to monitor blood sugar levels regularly while taking semaglutide to ensure optimal glycemic control and adjust other diabetes medications as needed.

In addition to taking semaglutide as prescribed, individuals following a weight loss program with this medication should also focus on adopting healthy lifestyle habits, such as eating a balanced diet, staying physically active, and getting regular sleep. Semaglutide is not a stand-alone treatment for weight management but is intended to be used in conjunction with diet and exercise to achieve and maintain weight loss goals.

Potential Side Effects

As with any medication, there are potential side effects to be aware of when using semaglutide for weight loss. Common side effects of semaglutide may include nausea, diarrhea, vomiting, constipation, abdominal pain, and decreased appetite. These side effects are usually mild and may improve over time as the body adjusts to the medication. If side effects persist or worsen, it is important to contact a healthcare provider for further evaluation and management.

In rare cases, more serious side effects may occur with the use of semaglutide, such as pancreatitis, gallbladder problems, kidney problems, allergic reactions, and thyroid tumors. It is important to seek immediate medical attention if any unusual or severe symptoms develop while taking semaglutide. Healthcare providers will monitor for these potential side effects and adjust treatment as needed to ensure the safety and well-being of individuals using this medication for weight loss.

Overall, semaglutide can be a valuable tool in weight loss programs for individuals who have struggled to lose weight through diet and exercise alone. By following a prescribed dosage chart, monitoring blood sugar levels, adopting healthy lifestyle habits, and being aware of potential side effects, individuals can work with healthcare providers to achieve successful weight loss outcomes with the help of semaglutide.

Conclusion

When used as part of a comprehensive weight loss program, semaglutide can be a beneficial tool for individuals seeking to achieve and maintain a healthy weight. By working with healthcare providers to follow a prescribed dosage chart, monitor blood sugar levels, adopt healthy lifestyle habits, and be aware of potential side effects, individuals can maximize the effectiveness of semaglutide in their weight loss journey. With the right support and guidance, semaglutide can help individuals overcome barriers to weight loss and improve their overall health and well-being.

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If you’re eating your protein, tracking your macros, and still not seeing results—this is the follow-up episode you didn’t know you needed. Chalene breaks down the biggest protein mistakes people are making, especially women over 40, that could be sabotaging fat loss, metabolism, and muscle gains. Backed by science and real-life experience, she uncovers the one change that helped her drop weight and reduce the stress around food. If you're ready to age powerfully and stop guessing with your nutrition, this episode is packed with eye-opening truths. Watch more videos like this 👇 How Much Protein Do You Really Need?: https://youtu.be/jXSaR0ZG21w?si=9dnVZ2jFkqCqHKKu I Eat These Foods Every Day and DON’T GAIN WEIGHT (Over 50): https://youtu.be/y7q4ofpDHJc How To Stay On A Healthy Track When Life Gets Crazy: https://youtu.be/MdrQLOzerBA I Dropped 10% Body Fat With This Diet Plan: https://youtu.be/3L7dyY7VOhU Links in the video: 🎉 Come to Camp Be More!! Reclaim Your HEALTH. It’s Time for Your MIDLIFE MAKEOVER! 👉 http://phaseitup.com/campbemore 🎯 Try MASSZYMES – a 100% plant-based digestive enzyme blend that boosts nutrient absorption and speeds up muscle recovery 👉 https://chalene.com/digest 💪🏼 You're Too Young To Feel Old! Join the all-new Phase It!! A Personalized Plan to Fit Your Life 👉 Go to https://phaseitup.com What You’ll Learn ⬇️ ➡️ Why you might be over-consuming calories even when tracking macros ➡️ The difference between setting protein goals based on ideal weight vs. lean body mass ➡️ The truth about muscle loss and why protein timing matters ➡️ What the protein leverage hypothesis is and how it may be sabotaging your satiety ➡️ How to simplify your nutrition without obsessing over numbers or math ➡️ Why protein is even more important during perimenopause and menopause ➡️ What the latest research says about post-workout recovery + metabolism ➡️ How to build muscle, boost your metabolic rate, and finally lose body fat — not just weight 🤩 Check Out Dr. Stephanie Estima ► YouTube: https://www.youtube.com/@DrStephanieEstima/videos ► Podcast: https://podcasts.apple.com/us/podcast/better-with-dr-stephanie/id1479074542 💪🏼 Inbody Scale - https://amzn.to/4i5lE11 Fat Loss Full Playlist ► https://youtube.com/playlist?list=PLb8hDoRky2_KB1KDL4h3JnxRjr0DXYrLk&si=IVzDB-WD1-OIEeha 🤓 Research: Protein intake and metabolism ➜ https://health.clevelandclinic.org/protein-deficiency-symptoms Post-workout protein consumption and satiety. ➜ https://pmc.ncbi.nlm.nih.gov/articles/PMC7824960/ https://pmc.ncbi.nlm.nih.gov/articles/PMC7539343/#sec10 https://pubmed.ncbi.nlm.nih.gov/37935299/ ➜ Lean body mass vs. total weight to calculate protein needs https://pmc.ncbi.nlm.nih.gov/articles/PMC9066312/ ➜ Low vs. high protein diets https://pmc.ncbi.nlm.nih.gov/articles/PMC11091325/ ➜ Protein leverage hypothesis https://royalsocietypublishing.org/doi/10.1098/rstb.2022.0212 ➜ Even distribution of protein across meals https://pubmed.ncbi.nlm.nih.gov/38563983/ https://jses.net/wp-content/uploads/2022/03/Roberts-et-al.-2022.pdf ======================== For more resources and tips, join me on Patreon ➜ http://chalene.com/more And don't forget to join my weekly newsletter for lifestyle tips and deals of the week: ➜ https://chalene.com/newsletter Let’s Connect... Website ➜ https://chalene.com Instagram: ➜ https://www.instagram.com/chalenejohnson TikTok: ➜ https://www.tiktok.com/@chalenejohnson

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