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Semaglutide, a once-a-week injection used to treat type 2 diabetes, has recently gained attention for its potential as a weight-loss aid. In fact, studies have shown that patients taking semaglutide have experienced significant weight loss, making it an attractive option for those struggling to shed pounds. However, determining the right dose of semaglutide for weight loss can be a complex process that requires careful consideration of several factors.
Factors to Consider When Determining Semaglutide Dose for Weight Loss
When it comes to determining the appropriate dose of semaglutide for weight loss, several factors need to be taken into account. One of the most important considerations is the patient’s starting weight and weight loss goals. Patients who are significantly overweight may require a higher dose of semaglutide to see results, whereas those who are only looking to lose a few pounds may benefit from a lower dose.
Another important factor to consider is the patient’s overall health and medical history. Patients with certain medical conditions, such as kidney or liver disease, may need to be prescribed a lower dose of semaglutide to prevent any potential complications. Additionally, patients taking other medications that could interact with semaglutide may also need a modified dose.
It’s also crucial to consider the patient’s tolerance to the medication when determining the dose of semaglutide for weight loss. Some patients may experience side effects, such as nausea or diarrhea, when taking semaglutide, which could impact their ability to stick to the prescribed dose. In these cases, a lower dose may be necessary to minimize side effects while still promoting weight loss.
Guidelines for Prescribing Semaglutide for Weight Loss
When prescribing semaglutide for weight loss, healthcare providers should follow specific guidelines to ensure the safety and effectiveness of the treatment. The recommended starting dose of semaglutide for weight loss is typically 0.25 mg once weekly, with the option to increase to 0.5 mg after four weeks if necessary. Patients should be monitored closely for any side effects or changes in weight during the initial weeks of treatment.
In some cases, healthcare providers may recommend a higher dose of semaglutide for patients who have not seen significant weight loss after several weeks of treatment. However, it’s essential to balance the potential benefits of a higher dose with the increased risk of side effects. Healthcare providers should work closely with patients to adjust their dose as needed based on their individual response to the medication.

Patients prescribed semaglutide for weight loss should also receive comprehensive counseling on diet, exercise, and lifestyle changes to maximize the effectiveness of the treatment. While semaglutide can help promote weight loss, it is not a standalone solution and should be used in conjunction with other healthy habits to achieve long-term success.
Frequently Asked Questions About Semaglutide Dosing for Weight Loss
Q: How long does it typically take to see results from semaglutide for weight loss? A: Patients may start to see weight loss results within the first month of treatment, with significant progress typically seen after three to six months of consistent use.
Q: What are the common side effects of semaglutide for weight loss, and how can they be managed? A: Common side effects of semaglutide include nausea, diarrhea, and constipation. These side effects can often be managed by starting with a lower dose and gradually increasing as tolerated.
Q: Are there any restrictions on who can take semaglutide for weight loss? A: Semaglutide is not recommended for pregnant or breastfeeding women, individuals with a history of pancreatitis, or those with a personal or family history of medullary thyroid carcinoma.
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#mounjaro #Weightloss #Tirzepatide #zepbound This video has been a LOOOOOOONG time in the making. I am soooo excited that I got to do it... finally! Like, Comment & Subscribe... Thank you! My other channel (with my wife): @YoKendog ---------------------- FOLLOW ME: Instagram: 2BeFatNoMore MyFitnessPal: Eat2LiveInOKC _______________________ I am paying full price, out of pocket, for Mounjaro. If you would like to help me continue my journey: Venmo - https://www.venmo.com/u/KEDOGN PayPal - [email protected] Cash App - $Kedogn Any and all donations are very appreciated. _______________________ This is my story... I have struggled with weight issues for most of my life. I'd lose some, then gain it and more back every time. I have tried it all: fasting, Weight Watchers, NutriSystem, Herbalife, Slimfast, Adkins, South Beach... you name a fad diet in the past 30 years and I have probably tried it and FAILED! In late December 2021 my wife and I moved to Oklahoma City for work. I looked at this as a 'fresh new start' and I decided that I was going to start a new diet/lifestyle just after the first of the year and so on January 10, 2022, I made the change I needed to and that lasted about a month. I struggled HARD to lose weight. In April of that year I hurt my right knee really bad and had to see a specialist about that. He gave me this look after checking out my knee, and then he looked away towards the wall. He did this a couple times until *I* finally said to him, "Doc are you telling me I need to lose weight?" and he replied something fancy that essentially meant "YES!!". That started me right there on a journey. I **HAD** to lose weight. He was the FIRST ever doc to tell me that, so this would be my motivation... however, a stop by Taco Bell on the way home first was needed since I would be 'going without'. Over the next 4 months I lost and maintained a loss of just 35lbs when I finally set up an appointment with my new Primary Care Physician. I dreaded that appointment as I just knew that she would want to talk about weight and sure enough, about 15 minutes into it she asked me about my weight and if I was interested in losing it. I told her "it's not like I enjoy having it, Doc". She then mentioned Mounjaro to me and I fought her on it immediately. I told her I didn't want to inject into my body something that wasn't meant for it, being that Mounjaro was a medicine for those with Type 2 Diabetes, and I didn't have that. She understood and eventually talked me into trying it. I gave in, reluctantly, and I agreed to 3 months. I told her that if it didn't work in 3 months, I don't want to hear anything else from her again about my weight. That I would give it my best for those 3 months and if it fails, it fails and nothing else can be said. I took my first Mounjaro shot around 9:15am on September 2, 2022 and I weighed 560lbs at that time. Videos on this channel detail my journey from then until now as I have lost over 263lbs since that first shot, even though I have not been able to take the medication as prescribed for various reasons, one being cost. This medicine really is life changing and these videos are the story of how Mounjaro changed my life for the better....#mounjaro ..
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Obesity expert Dr Holly Lofton reviews three alternatives to GLP-1s to help patients drop excess weight. https://www.medscape.com/viewarticle/1000474?src=soc_yt -- TRANSCRIPT -- Hi. I'm Dr Holly Lofton. I'm a board-certified obesity medicine specialist, and I direct the medical weight management program at NYU Langone Health. There is so much information about glucagon-like peptide 1 (GLP-1) agonists as anti-obesity medications. I bet you can't think of a single person who hasn't heard of them, and many of your friends or family members may have even tried them. However, we also have what we call the first generation of medications for weight management, and I'll talk about some of those today. Phentermine. If your patient is not able to tolerate a GLP-1 agonist or is unable to access these medicines for various reasons, one option is phentermine, which has been around for decades. It is an oral medication that's usually taken once a day in the morning. It is a classic appetite suppressant. Phentermine makes people feel less hungry. It also gives people a little more energy, so they're able to increase their activity while creating a caloric deficit, and this leads to weight loss over time. Phentermine differs from the GLP-1 agonists, which are intended for chronic weight management. The FDA has approved phentermine for short-term weight loss; its use is recommended for no more than 12 weeks at a time. The medication comes in doses ranging from 8 mg to 37.5 mg and is usually slowly titrated up depending on tolerance and effect. Side effects that are most often reported include a racing heart, insomnia, agitation, and dry mouth. This drug is not for everyone. Phentermine is contraindicated in those with uncontrolled hypertension, with cardiac disease (such as a history of heart attack), or who are at high risk for heart attack or stroke. Some drug interactions can occur, which should be considered on a case-by-case basis. Phentermine may be an option for your patients if an elevated appetite is keeping them from losing weight. It should be used as an adjunct to lifestyle recommendations, which means eating fewer calories and increasing activity. Phentermine-Topiramate. Another non–GLP-1 agonist medication indicated for obesity is phentermine-topiramate [Qsymia]. This is another oral medication. The idea behind combining these two medications is that they can generate more appetite suppression without the high potential for side effects of phentermine alone, such as agitation, increased heart rate, or increased blood pressure. Topiramate is used for migraine or seizure prevention. One side effect of topiramate is unintentional weight loss, so they decided to combine phentermine with topiramate in one pill. Phentermine-topiramate comes in four different doses and is usually titrated up from the lowest to the highest dose. People who can't tolerate the higher doses of phentermine are able to tolerate Qsymia because the dose of phentermine is lower. This medication came to the market in 2012, after the SEQUEL trial, which demonstrated its safety and efficacy, achieved about 12% weight loss, which for many years was the highest weight loss seen with any other anti-obesity medications on the market. Because this is a combination medication, it has some potential side effects and contraindications. For example, we don't give phentermine-topiramate to people with uncontrolled hypertension or anxiety, and it is contraindicated in those with glaucoma. We don't give this medication to anyone who has had adverse reactions or hypersensitivity to either of the ingredients. Because the combination contains topiramate, it should not be prescribed to anyone with childbearing potential unless they are using an effective form of hormonal contraception or even two effective forms. Topiramate can increase the risk of having a baby with a cleft palate by five times if they become pregnant while taking this medication. Phentermine-topiramate is dosed once daily. One commonly reported side effect is paresthesia: numbness and tingling of the fingers and toes that can manifest as feeling very cold when it's cold outside. Although some patients report paresthesia, most say that it's not so intolerable that they want to discontinue the medication. There have been reports of vision changes in people taking phentermine-topiramate; if severe vision changes occur, it is recommended to discontinue the medication. Transcript in its entirety can be found by clicking here: https://www.medscape.com/viewarticle/1000474?src=soc_yt
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