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New evidence brings more good news about the unanticipated effects of the GLP-1 receptor agonists. https://www.medscape.com/viewarticle/glp-1-drugs-might-cut-dementia-risk-half-2025a10008bs?src=soc_yt -- TRANSCRIPT -- Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I’m Dr F. Perry Wilson from the Yale School of Medicine. It’s quite a thing that we live in an era with the biggest blockbuster weight-loss drugs in history, and I can look at you straight-faced and say, yeah, but honestly that’s not the most interesting thing about the GLP-1 receptor agonists such as Ozempic. Beyond their clear utility in weight loss, we have good data that demonstrate the drugs lead to improvements in rates of heart disease, liver disease, and even all-cause mortality, and intriguing reports of strange off-target effects: a reduction in gambling, drinking, drug use, smoking, and compulsive shopping. It’s honestly hard to find an organ system or self-destructive behavior that GLP-1 drugs don’t seem to improve somehow. It’s almost strange. It’s as if the statins came out and everyone was excited about the cholesterol going down, and then we discovered that they reversed hair loss or took three strokes off your golf game. How does one drug do so many things? I think the behavioral changes are the clue. The fact that people may drink or smoke less on these drugs should tell you that something is happening in their brains. And if these drugs are acting on the brain, you might well wonder if they can reduce the risk for brain disease — dementia. And, at least according to a new study, the answer appears to be yes. As the GLP-1 drugs started getting more and more popular, I decided to perform some due diligence and refresh what I had learned in med school about this thing called “glucagon-like peptide.” These drugs bind to the same receptor that GLP does, primarily to cause the pancreas to release more insulin when blood sugar is high. But we have plenty of drugs that stimulate insulin release. And they don’t seem to have all these other weird effects. So, what’s going on? When a drug acts on a specific receptor, it is worth seeing what cells in the body have that receptor, and this is a pretty interesting figure that shows that. You see high expression in the pancreas — no surprise. But next is expression in the heart muscle — interesting, considering these drugs have been shown to reduce the risk for heart disease. Then the salivary glands, and then… the cerebral cortex. The brain. And not just any part of the brain, the thinking part of the brain. A lot happens when these drugs bind to a receptor on a cell. But the brain is a mysterious and important organ. In contrast, the heart is relatively simple, and there are multiple randomized trials that show that GLP-1 drugs, as well as some other drugs for diabetes, such as the SGLT2 inhibitors, pioglitazone, and metformin, reduce the risk for cardiovascular disease in people with diabetes. So, it makes sense to ask whether these drugs would do the same for brain disease. Enter this study, "Cardioprotective Glucose-Lowering Agents and Dementia Risk," from Catriona Reddin and colleagues in JAMA Neurology. It’s an impressive bit of work combining data from 23 different randomized trials of these drugs including more than 150,000 individual people, to determine whether they reduce the risk for dementia. This is the best evidence we have to date for a neuroprotective effect of GLP-1 inhibitors. And this is the only type of study that could give us this evidence. The reason you need to combine so much data to detect a signal is that, to date, no randomized trials of GLP-1 drugs have been designed with dementia as a primary outcome. Transcript in its entirety can be found by clicking here: https://www.medscape.com/viewarticle/glp-1-drugs-might-cut-dementia-risk-half-2025a10008bs?src=soc_yt
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The television show Shark Tank, where entrepreneurs pitch their business ideas to a panel of wealthy investors, has made its mark on different industries throughout its tenure. One of those industries that Shark Tank has had a significant impact on is the keto diet industry. The keto diet, short for ketogenic diet, is a diet that is high in fat and very low in carbs that has become quite popular in recent years due to its purported health benefits, including weight loss and improved mental clarity. In this article, we are going to delve into how Shark Tank impacts the keto diet industry and helped it reach its present-day state and success.
The Power of Shark Tank
The US show Shark Tank can launch an enterprise into a skyrocketing trajectory of success for its entrepreneurs, aided by a shot at national visibility and assistance through funding from the show’s panel of investors, aptly termed ‘sharks’. For any company that makes the big-leagues cut and ultimately wins over the sharks, the publicity tends to lead to a considerable spike in sales and brand awareness for the company. Especially for a niche market product such as Keto Chow, having publicity on a national TV show can provide valuable exposure.
Another aspect of Shark Tank’s impact on the keto diet involves accelerating innovation in the keto diet space by bringing new production methods and services to consumers. Shark Tank entrepreneurs have brought a variety of products to the market, from keto-friendly snacks and supplements, to meal delivery services and keto cookbooks. On Shark Tank, they receive exposure and reach consumers who are following or interested in the ketogenic diet.
Further, the volume of feedback and potential investment that the sharks offer these keto businesses helps improve their scope and enhance the offerings. The investors on Shark Tank come with hard-won industry knowledge, experience and the financial resources that can help the nascent business become a sustainable enterprise and break into the market against the fierce competition. A shark ‘yes’ could be what gives the niche keto business the platform and prominence to stand out from a noisy crowd of enthusiasts, and find an eager population of loyal customers searching for intelligent, quality innovation.
Success Stories from Shark Tank
Several keto businesses that have appeared on Shark Tank have seen huge growth following their appearance on the show. After appearing on the TV pitch show, Nui secured an investment from one of the Sharks. Based in New York, Nui makes low-carb, high-fat cookies that are keto-friendly. A state-wide ice cream company he started after graduation was short-lived Nui has seen huge sales and brand growth post-Shark Tank due to the exposure; its product line has expanded, and it now takes up a prime spot also as a leader in the ever-growing keto snack sector.
Another triumph belongs to Kettle Fire, which sells bone broth products. That’s a savoury favourite of keto dieters. With its natural health appeal, no carbs and a spike in demand based on strong on-air sales on Shark Tank, it recently received an investment from one of the sharks and expanded distribution channels to reach a wider customer base.
Much of this is down to Shark Tank, which has unambiguously been a catalyst, not just for keto products but for the entrepreneurship of keto businesses. Shark Tank’s visibility has brought new keto foods and services to market and provided incubation for future generations of keto entrepreneurs. Locating pro-keto founders that receive the Sharks’ endorsement and capital, even when the products were only peripherally related to keto, were scrutinised for their commitment and passion.
Conclusion
To conclude, the keto diet business benefits greatly from Shark Tank, as the show features valuable innovations of foods and services for people being on a ketogenic diet. In consequence, these entrepreneurs are able to develop and expand their businesses at the back of the show’s capabilities to offer exposure and investment. Moreover, keto products that succeed can quickly expand into a national or even worldwide product. This allows consumers the opportunity to consume low-carb, high-fat products – and for these producers, it allows them to expand into a market they likely wouldn’t have reached on their own. With Shark Tank continuing to spotlight entrepreneurs on their passion for bringing people to the ketogenic lifestyle and exhausting their desire and efforts in investing in their success, we can understand greater keto business growth and continue to witness innovation in the keto market, ultimately benefiting both those who run the business and, just as importantly, those who seek the ketogenic lifestyle.
Thank you for reading the Journalist’s Resource article on ‘Shark Tank’ Turbocharges the Keto Diet With High Fibre Breads and Cheese Nuggets’. Please let us know if you use this resource and if you have questions or would like to discuss further. If you would like to read more articles on the latest trends and developments in the keto diet industry, please visit our website.
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Are you looking for a delicious and convenient way to stay on track with your ketogenic diet? Look no further than Let’s Keto Apple Gummies! These tasty treats are the perfect snack to satisfy your cravings while still keeping you in ketosis. Packed with flavor and low in net carbs, our Apple Gummies are a guilt-free indulgence that you can enjoy anytime, anywhere.
The Perfect Keto Snack
Let’s Keto Apple Gummies are specially formulated to fit into your keto lifestyle. Each gummy is sweetened with natural ingredients like stevia and erythritol, so you can enjoy a tasty treat without worrying about spiking your blood sugar levels. With only 2g of net carbs per serving, these gummies are the perfect guilt-free snack to keep you on track towards your health and fitness goals.
These Apple Gummies are also a convenient option for on-the-go snacking. Whether you’re at work, traveling, or just relaxing at home, you can easily pop a few gummies into your mouth for a quick and satisfying pick-me-up. Say goodbye to the hassle of preparing complicated keto-friendly snacks – Let’s Keto Apple Gummies are ready to eat whenever you need a delicious bite.
Not only are these gummies delicious and convenient, but they’re also made with high-quality ingredients that support your overall health. Let’s Keto prioritizes using natural and clean ingredients in our products, so you can feel good about what you’re putting into your body. Our Apple Gummies are free from artificial flavors, colors, and preservatives, making them a wholesome choice for your keto diet.
A Versatile Treat for Every Occasion
Let’s Keto Apple Gummies are a versatile treat that can be enjoyed in various ways. Whether you eat them on their own as a sweet snack, incorporate them into your favorite keto recipes, or use them as a topping for yogurt or ice cream, the possibilities are endless. Get creative and explore different ways to enjoy these delicious gummies while staying true to your keto lifestyle.
With Let’s Keto Apple Gummies, you no longer have to sacrifice flavor for your ketogenic diet. Indulge in the sweet taste of apples without worrying about derailing your progress. These gummies are a satisfying treat that will keep you on track towards your health and wellness goals. Try Let’s Keto Apple Gummies today and discover a new favorite snack that will elevate your keto experience.
FAQ
Q: Are Let’s Keto Apple Gummies suitable for people with dietary restrictions?
A: Yes, Let’s Keto Apple Gummies are keto-friendly, gluten-free, and made with natural ingredients. They are suitable for individuals following a ketogenic diet or those with gluten sensitivities.
Q: How many gummies come in a serving?
A: Each serving of Let’s Keto Apple Gummies contains approximately 10 gummies. This serving size is perfect for a quick and satisfying snack to curb your cravings.
Q: Can I eat Let’s Keto Apple Gummies if I have diabetes?
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In this modern era, the exclusively popular ketogenic diet continually racks up statistics of its proven capacity to facilitate weight loss as well as to upgrade one’s own health and well-being. Among the expansive market of available dietary supplements facilitating these measures of the keto diet is one product attracting the lion’s share of buying consumers, namely Pure BHB Keto, highlighted over on the Shark Tank show. The purpose of this article is to present a scientific review on Pure BHB Keto with particular emphasis on a review of supplement ingredients, its proposed mechanism of action, and its benefits in facilitating ketosis and thereby increased weight loss.
Ingredients of Pure BHB Keto
Pure BHB Keto is a keto dietary supplement that one of its active ingredients is beta-hydroxybutyrate (BHB), The loss of body weight occurs because of the ability of BHB to help the body to quickly enter the metabolic state in which fat is oxidized for fuel instead of carbs by forcing the body into ketosis.
Furthermore addition to BHB, Pure BHB Keto may have other ingredients to offer you. These ingredients may include vitamins, minerals and natural extracts that help with the overall development of the body. These other ingredients bring the whole formulation to a new level of effectiveness.
Mechanism of Action
When you ingest Pure BHB Keto, the BHB contained in the supplement is quickly transported into the bloodstream and then into the tissues of the body where it can be used as an energy-producing fuel source for the mitochondria. This means that Pure BHB Keto helps your body recreate the healthful metabolic state of ketosis – the process where your body’s energy sources switch from the usual glucose intake to utilizing fats for fuel.
Suppressing appetite and promoting ketosis, such as Pure BHB Keto can help you to burn fat more effectively and to lose more weight. Furthermore, ketones such as BHB can act as a neuroprotective agent, improve both cognitive function and human performance by restoring mitochondria and reducing inflammation in the body. This is why Pure BHB Keto helps you not only lose weight but also to support your general health and wellbeing.
Potential Benefits of Pure BHB Keto
Some of the advantages of taking Pure BHB Keto to enter a state of ketosis and lose weight is that it could help users get into a state of ketosis more quickly without having to follow such a strict low-carb diet. It can also be helpful if there are people who struggle to maintain a ketogenic diet for whatever the reason might be.
Ketones put your body into ‘ketosis’ – they are an additional form of fuel to help the body reach ketosis. Additionally, Pure BHB Keto can help those going through the keto flu, which is how people who start the keto diet feel before their bodies get used to a diet that’s low on carbs. Pure BHB Keto provides an extra helping hand, making us feel spirited and energetic again. The exogenous ketones such as BHB can help combat the fatigue and brain fog – symptoms experienced by many people who are starting the keto diet or during a carbohydrate withdrawal phase. With some extra help, it is easier to stick to the keto diet and achieve the goal of weight loss.
Conclusion
In summary, Pure BHB Keto has BHB as an active ingredient in a dietary supplement. Pure BHB Keto uses exogenous ketones to help you attain ketosis, and through that, it can assist with weight loss. You will be able to lose weight in a quicker manner because you have an external source of energy derived from fat, which sets you on the path for ketosis. Ketosis has many benefits for health and primarily weight loss. Although it is still important to have more research done on Pure BHB Keto so we understand the long-term effects of Pure BHB Keto’s ingredients on the body, the current body of research provides a strong enough foundation to state that Pure BHB Keto is an important tool for people who are looking for more effective ways to reach their weight loss and health goals.
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