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@East-Bound's personal recount of case: https://youtu.be/7BpymtR2vpA @East-Bound Interview: https://youtu.be/o15HCjtSkug @chubbyemu video on this case: https://youtu.be/ChPeG19qKUo @HemeReview Podcast version: https://anchor.fm/chubbyemu 2,4-Dinitrophenol (DNP) is a chemical that is not approved for weight loss in the United States. It is a classic case of efficacy, but without safety in the setting of weight loss. This setting of weight loss can be prone to chemical misuse, further exacerbating understanding in human systems. Christopher is one of 2 - 3 cases documented in literature to have survived an accident with DNP for weight loss. As of 2021, one organization has permission from the US FDA to investigate DNP in some neurodegenerative disorders. These are rare diseases with limited standards of care, therefore extenuating circumstances to find anything that could potentially improve patient outcomes. Tweet me: https://www.twitter.com/hemereview IG me: https://www.instagram.com/hemereview FB me: https://www.facebook.com/hemereview References: Role of dantrolene in dinitrophenol (DNP) : A continuing question? Am J Emerg Med. 2019 Jun;37(6):1216.e1-1216.e2. https://pubmed.ncbi.nlm.nih.gov/30948257/ 2,4-dinitrophenol (DNP): a weight loss agent with significant acute toxicity . J Med Toxicol. 2011 Sep;7(3):205-12. https://pubmed.ncbi.nlm.nih.gov/21739343/ Ambient temperature and mortality from unintentional . JAMA. 1998 Jun 10;279(22):1795-800. https://pubmed.ncbi.nlm.nih.gov/9628710/ Dinitrophenol as a Medicine. Cells. 2019 Mar; 8(3): 280. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468406/ The Interaction of Highly Active Uncouplers With Mitochondria. Biochimica et Biophysica Acta, 639 (1981) 225-242. Beware the yellow slimming pill: fatal 2,4-dinitrophenol. BMJ Case Rep. 2016 Apr 4;2016. https://pubmed.ncbi.nlm.nih.gov/27045052/ Dantrolene is not the answer to 2,4-dinitrophenol poisoning: more heated debate. BMJ Case Rep. 2018 Dec 19;11(1):e225323. https://pubmed.ncbi.nlm.nih.gov/30573533/ The effect of 2,4-dinitrophenol on adipose-tissue metabolism. Biochem J. 1969 Feb;111(4):431-44. https://pubmed.ncbi.nlm.nih.gov/4388239/ The mechanism of uncoupling of oxidative phosphorylation by 2,4-dinitrophenol. J Biol Chem. 1967 Oct 25;242(20):4577-83. https://pubmed.ncbi.nlm.nih.gov/4964808/ MECHANISMS OF DINITROPHENOL TOXICITY. Simon E.W. Biological Reviews. Vol 28. (4). Nov 1953. Identification and Importance of Brown Adipose Tissue in Adult Humans. https://www.nejm.org/doi/full/10.1056/NEJMoa0810780 Mitochondrial uncoupling as a target for drug development for the treatment of obesity. Obes Rev. 2001 Nov;2(4):255-65. https://pubmed.ncbi.nlm.nih.gov/12119996/ LC-MS-MS analysis of 2,4-dinitrophenol and its phase I and II metabolites. J Ana Toxicol. Jan-Feb 2007;31(1):55-61. https://pubmed.ncbi.nlm.nih.gov/17389084/ Uncouplers of oxidative phosphorylation. Environ Health Perspect. 1990 Jul;87:213-8. https://pubmed.ncbi.nlm.nih.gov/2176586/ Texas Woman Charged with Selling Misbranded https://www.fda.gov/inspections-compliance-enforcement-and-criminal-investigations/press-releases/texas-woman-charged-selling-misbranded-drug

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Keto Diet Deep Dive: Benefits, Risks & the Science Behind the Hype Ever wondered if the keto diet is your ultimate health hack? On this super short solo episode of Bodyholic with Di, we unravel the ketogenic diet's promises and pitfalls. Discover groundbreaking research from the British Journal of Nutrition and the Journal of Diabetic Medicine, revealing keto's impact on weight loss & blood sugar control. We even explore a 2008 Lancet study suggesting keto's potential for neurological conditions. But it's not all sunshine & bulletproof coffee. We tackle the reality of keto flu, sustainability challenges, and nutritional trade-offs. Learn why this diet, despite its benefits, might not be for everyone. Whether keto-curious or a seasoned dieter, this science-backed quickie equips you to make informed health choices. Tune in to Bodyholic with Di and transform your understanding of what keto can - or can't - do for you. Keywords: keto diet, ketogenic diet, weight loss, blood sugar control, keto flu, health benefits, nutritional trade-offs, science-backed, Bodyholic with Di

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(FDA Approved Injectable "Ares" Therapy) Our SEMAGLUTIDE THERAPY can help reduce hunger to prevent overeating and regulate glucose levels to help your body process sugars more effectively. BENEFITS: • Slow stomach emptying. When digestion is slowed down, nutrients in food are released more slowly. This prevents blood sugar from spiking after a meal. • Reduce sugar released from the liver. The liver can release extra sugar into the blood as needed. GLP-1 RAs prevent the liver from putting too much sugar into your bloodstream. — (FDA Approved Injectable Therapy) Our TIRZEPATIDE THERAPY is a once-weekly injectable peptide for weight loss therapy which mimics hormones that are involved in blood sugar control and appetite, that can help prevent you from overeating and curb your appetite. May also improve how well your body breaks down sugars and fat. It’s the next step up from the Semaglutide therapy without the potential nausea side effect. BENEFITS: When used along with an individualized low-calorie, low-fat diet and exercise program to help with weight loss, overweight adults who may also have high blood pressure, diabetes, or high cholesterol see significant progress across all health markers. This therapy may assist with weight loss by signaling to your brain that you are full- so you eat less. Tirzepatide also slows the movement of food through your stomach so that you feel fuller longer. Text or call for more info: 727-389-3220

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🚨 GLP-1s Aren’t Magic (Part 1)! Before jumping on GLP-1 meds, consider the risks: nausea, muscle loss, and rebound weight gain. Start with the foundation—high-protein meals + daily movement. Build healthy habits before meds do the work for you. What are your thoughts? SUBSCRIBE LIKE AND COMMENT BELOW #health #nutrition #dietitian #diet #lifestyle #GLP1 #weightloss #protein #fitness Ask ChatGPT

How Did Kelly Clarkson Lose Her Weight? Detailed Insights

Hey my loves! 💕 Welcome back to Episode 3 of my weekly weight loss diaries! This week, I’m diving into the real struggles, small wins, and the mindset shifts that are making all the difference in my fat loss journey. If you’re trying to lose weight, build a sustainable routine, or just need some fitness motivation, this is for you! 🚀 💬 Drop a comment below with your biggest struggle or question—I’d love to help! 🔥 Want to Work With Me as Your Coach? 💪 Apply for 1:1 Coaching: https://anongymgirl.thisisfortis.com/enquire-with-me 📩 Join My Newsletter for Exclusive Tips & Updates: https://anongymgirl.thisisfortis.com/newsletter 💸 My Favourite Discounts: 🛍️ ESN Supplements – Use code ANON for a discount! ➡️ https://uk.esn.com/discount/ANON 🛍️ Gymshark Activewear – Use code ANON10 for 10% off! ➡️ https://uk.checkout.gymshark.com/ANON10 ✨ Let’s Connect! 📸 Instagram: @TheAnonGymGirl 🎥 TikTok: @TheAnonGymGirl 📩 For business inquiries: [email protected] #weightloss #weightlossjourney #fatloss #fitnessmotivation #caloriedeficit #healthylifestyle #gymmotivation #losingweight #sustainableweightloss #howtoloseweight #weightlossvlog #weightlossupdate #weightlossprogress #losingfat #fatlossplan #fitnessjourney #nutritiontips #fitnesscoach #strengthtraining #workoutmotivation #healthyhabits #bodyconfidence #discipline #consistencyiskey #mindsetmatters

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【夏までに5㎏痩せる~1分間エクササイズ~】 ★★★Day28★★★ 夏までに5㎏痩せるを目標に1日1分間でできるエクササイズを毎日アップしています! ダイエットはチリツモが大事!だから毎日1分で良いので運動する習慣を身につけましょう💛 今日は1日1分で下半身痩せできるエクササイズ☺ 【exercise1】 壁や椅子に手をついて、膝を曲げたまま足を真横に上げます。 足を上げたままで10回繰り返します。 【exercise2】 次に股関節を大きく外回しします。 こちらも10回繰り返します。 できるだけ大きく回すのがポイント☝ 【exercise3】 最後は膝を伸ばしたまま真横に10回上げます。 最後まで足を上げたままで行います。 この動きを1セットとし、終わったら逆の足にチェンジします。 見た目以上にきついけど、下半身が引き締まってきますよ☺ 夏に向けて毎日コツコツ頑張ろう🔥 *************************** 62歳のおばちゃんが人生最後のダイエットを頑張っています。 ▶もっと効果的なエクササイズも沢山公開しています!是非チャンネルも見に来てね♬ ▶感想・コメント頂けると嬉しいです。 *************************** #ダイエット #ダイエット仲間募集 #公開ダイエット #公開ダイエット日記 #公開ダイエット仲間募集 #更年期ダイエット #リベンジダイエット #リバウンドからの再スタート #宅トレ #すき間エクササイズ #下半身痩せ #脚痩せ #ヒップアップ #還暦女子 #還暦ダイエット挑戦中 #還暦ダイエット挑戦 #50代ダイエット #60代ダイエット #いつまでも綺麗でいたい

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