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In this episode, Kim welcomes back Dr. Michelle Tubman to the podcast for an in-depth discussion on the popular GLP-1 agonists, such as Ozempic and Wegovy. Dr. Tubman, a physician specializing in emergency, obesity, and lifestyle medicine, breaks down everything you need to know about these medications: How injectable weight loss drugs work Side effects - both short and long termTheir effectiveness in facilitating long term weight loss and improved health outcomesMisconceptio...

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gip and glp GIP and GLP are abbreviations for two important hormones involved in the regulation of blood sugar levels and digestion: glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 (GLP-1). GIP (Glucose-Dependent Insulinotropic Peptide): GIP is a hormone secreted by cells in the small intestine in response to the ingestion of carbohydrates, particularly glucose and fat. Its primary role is to stimulate the release of insulin from pancreatic beta cells. GIP is considered an incretin hormone because it enhances the secretion of insulin from the pancreas in a glucose-dependent manner, meaning it is released when blood glucose levels are elevated. GIP also inhibits glucagon secretion from the pancreatic alpha cells and promotes the storage of fat in adipose tissue. GLP-1 (Glucagon-Like Peptide-1): GLP-1 is a hormone secreted by cells in the small intestine, specifically the L cells, in response to the presence of nutrients in the digestive system. GLP-1 has multiple effects on the body. One of its primary roles is to stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner. It also inhibits glucagon release from pancreatic alpha cells, which helps to lower blood glucose levels. GLP-1 slows down the emptying of the stomach, which can contribute to a feeling of fullness and aid in appetite control. Additionally, GLP-1 has been found to promote the growth and proliferation of beta cells in the pancreas. Both GIP and GLP-1 play crucial roles in the regulation of glucose metabolism and the control of blood sugar levels. They are part of the incretin system, which is involved in the fine-tuning of insulin and glucagon secretion based on the nutritional status of the body. These hormones have also gained attention in the management of type 2 diabetes, as medications known as GLP-1 receptor agonists and DPP-4 inhibitors that target these pathways have been developed to help regulate blood sugar levels in individuals with diabetes @umerfarooqbiology7083 #gip #glp1 #obesity #muhammadumerfarooqbiology

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