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For this week’s Metabolic Classroom lecture, Dr. Bikman focuses on natural ways to boost GLP-1 (Glucagon-Like Peptide-1), a powerful gut hormone involved in appetite control, blood sugar regulation, and metabolic health. Ben begins by explaining that GLP-1 is secreted in response to food intake, influencing glucagon suppression, slowing gastric emptying, and activating satiety centers in the brain. However, research shows that individuals with obesity tend to have a blunted GLP-1 response, particularly after consuming carbohydrates. This means that people with obesity may not experience the same level of fullness and appetite regulation, which can contribute to overeating. Dr. Bikman then discusses concerns with GLP-1 receptor agonist medications, such as Ozempic and Wegovy. While they effectively promote weight loss, they also come with significant downsides, including loss of lean mass (up to 40% of total weight lost), increased mental health risks (depression, anxiety, and suicidal thoughts), and a return of sweet cravings over time. Additionally, 70% of people discontinue these drugs within two years, often regaining weight—primarily as fat—due to muscle loss during treatment. He then presents natural methods to enhance GLP-1 production without drugs. His lab at BYU found that Yerba Mate significantly increases GLP-1 by 40-50%, likely due to its ferulic acid content and bitter taste receptors that also reduce sweet cravings. Allulose, a rare sugar, has also been shown to stimulate GLP-1 and improve glucose control, even in individuals with type 1 diabetes. Other natural boosters include a low-carbohydrate, protein-rich diet, which triples GLP-1 levels compared to a low-fat diet, collagen peptides, which enhance GLP-1 secretion and insulin sensitivity, and quality sleep, since poor sleep is linked to impaired GLP-1 signaling and increased hunger. Dr. Bikman concludes by emphasizing that leveraging diet and lifestyle changes is the most effective and sustainable way to improve GLP-1 levels, regulate appetite, and support long-term metabolic health. While GLP-1 medications may serve a purpose, particularly for those struggling with carbohydrate cravings, they come with risks that should not be ignored. Instead, strategies such as Yerba Mate, allulose, low-carb diets, collagen peptides, and better sleep can provide natural, lasting benefits without side effects. Show Notes/References: For complete show notes and references referred to in this episode, we invite you to become a Ben Bikman Insider subscriber. As a subscriber, you’ll enjoy real-time, livestream Metabolic Classroom access which includes live Q&A with Ben, ad-free Metabolic Classroom Podcast episodes, show notes and references, Ben’s Research Reviews Podcast, and a searchable archive that includes all Metabolic Classroom episodes and Research Reviews. Learn more: https://www.benbikman.com (Auto-Translate Note: You can click the gear icon at the bottom of this video to auto-translate captions. For example, to translate into Polish, select Subtitles, choose Auto-Translate, then first choose English, then choose Auto-Translate again, then choose Polish.) #GLP1 #WeightLoss #Ozempic #Wegovy #MetabolicHealth #AppetiteControl #YerbaMate #LowCarbDiet #FatLoss #Allulose #BloodSugarControl #InsulinResistance #HormonalBalance #DrBenBikman #NaturalHealth #Type2Diabetes #CollagenPeptides #KetogenicDiet #MetabolicFlexibility #HealthyLiving #GLP-1 Timestamps (approximate): 00:59 - The Role of GLP-1 in Appetite & Blood Sugar Control 02:16 - GLP-1 & Glucagon Suppression: Balancing Blood Sugar 03:24 - How GLP-1 Affects Hunger & Satiety Through the Brain 06:43 - Why Obese Individuals Have a Blunted GLP-1 Response 10:09 - GLP-1 Medications: Benefits & Serious Concerns 14:19 - Yerba Mate: A Natural GLP-1 Booster (Study from Dr. Bikman’s Lab) 16:24 - Allulose: A Rare Sugar That Enhances GLP-1 & Blood Sugar Control 18:59 - How Low-Carb Diets Naturally Boost GLP-1 by 3x 21:40 - Collagen Peptides & Their Unexpected GLP-1 Benefits 23:05 - Sleep & Circadian Rhythm’s Role in GLP-1 Regulation 24:22 - Conclusion: The Best Natural Ways to Enhance GLP-1 Ben’s favorite yerba maté and fiber supplement: https://ufeelgreat.com/usa/en/c/1BA884 Ben’s favorite meal-replacement shake: https://gethlth.com (discount: BEN10) Ben’s favorite electrolytes (and more): https://redmond.life (discount: BEN15) Ben’s favorite allulose source: https://rxsugar.com (discount: BEN20) Ben’s favorite health check-up for women: https://choosejoi.co/drben15 (discount: DRBEN15) Ben’s favorite health check-up for men: https://blokes.co/drben15 (discount: DRBEN15) Ben’s favorite exogenous ketone: https://www.americanketone.com (discount: BEN10) Ben’s favorite dress shirts and pants: https://toughapparel.com/?ref=40 (use BEN10 for 10% off) Other products Ben likes: https://www.amazon.com/shop/benbikmanphd Learn more about becoming an Insider on our website: https://www.benbikman.com
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Weight loss pills have become a popular option for people looking to shed some extra pounds. With so many options available on the market, it can be overwhelming to choose the right one. One option that many people consider is prescription weight loss pills. While these pills can be effective in helping individuals lose weight, they also come with risks and side effects that need to be carefully considered.
Are Prescription Weight Loss Pills Safe?
Prescription weight loss pills are only recommended for individuals who are considered obese or have serious health risks due to their weight. These pills are usually prescribed by a doctor after a thorough evaluation of the patient’s overall health and weight loss goals. It is important to follow the doctor’s instructions carefully and monitor any potential side effects closely. Common side effects of prescription weight loss pills include increased heart rate, high blood pressure, and insomnia.
It is essential to remember that prescription weight loss pills are not a magic solution to weight loss. They work best when combined with a healthy diet and regular exercise routine. It is also crucial to understand that these pills are not suitable for everyone, and it is essential to discuss any concerns or questions with a doctor before starting a prescription weight loss pill regimen.
While prescription weight loss pills can be effective in helping individuals lose weight, they should not be the only method used. Lifestyle changes, such as eating a balanced diet and incorporating regular physical activity, are essential for long-term weight loss success. It is crucial to approach weight loss as a holistic journey that involves both physical and mental well-being.
How Do Prescription Weight Loss Pills Work?
Prescription weight loss pills work in various ways to help individuals lose weight. Some pills work by suppressing appetite, making it easier for individuals to eat less and feel full faster. Others work by blocking fat absorption, preventing the body from absorbing calories from fat. Some pills may also increase metabolism, helping the body burn calories more efficiently.
It is essential to understand that prescription weight loss pills are not a one-size-fits-all solution. Different pills work in different ways, and what works for one individual may not work for another. It is crucial to consult with a doctor to determine the best option for individual weight loss goals and health needs.
Overall, prescription weight loss pills can be an effective tool for individuals looking to lose weight. However, it is essential to approach their use with caution and under the guidance of a healthcare professional. By combining the use of prescription weight loss pills with lifestyle changes, individuals can achieve long-term weight loss success.
Common Questions About Prescription Weight Loss Pills
1. Are prescription weight loss pills safe for everyone?
Prescription weight loss pills are not suitable for everyone and should only be used under the guidance of a healthcare professional. Individuals with certain health conditions or medications may not be candidates for prescription weight loss pills.
2. What are the common side effects of prescription weight loss pills?

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Common side effects of prescription weight loss pills include increased heart rate, high blood pressure, and insomnia. It is essential to monitor any side effects closely and consult with a doctor if any concerns arise.
3. Can prescription weight loss pills be used as a long-term solution?
Prescription weight loss pills are not recommended for long-term use and should be used in conjunction with lifestyle changes for sustainable weight loss. It is essential to discuss long-term weight loss goals with a doctor to develop a holistic approach to weight loss.
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While many people are familiar with the use of CBD products for pain relief or anxiety management, the potential benefits of CBD for erectile dysfunction (ED) are lesser known. Ultra CBD gummies have gained popularity in recent years as a natural remedy for a variety of health issues, including ED. In this article, we will explore the potential of Ultra CBD gummies as part of a comprehensive weight management plan to address ED.
The Role of CBD in ED
CBD, or cannabidiol, is a compound found in cannabis plants that has been shown to have a wide range of potential health benefits. Research suggests that CBD may help improve blood flow and circulation, which are key factors in achieving and maintaining an erection. Additionally, CBD is known for its anti-inflammatory properties, which may help reduce inflammation in the body and improve overall health and wellness.
When it comes to ED, a variety of factors can contribute to the condition, including stress, anxiety, and poor circulation. By incorporating Ultra CBD gummies into a comprehensive weight management plan, individuals may be able to address some of these underlying issues and improve their overall sexual health.
It is important to note that while CBD shows promise in the treatment of ED, more research is needed to fully understand its effects on sexual health. As with any supplement, it is always best to consult with a healthcare provider before incorporating Ultra CBD gummies into your routine.
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Weight management plays a significant role in overall health and wellness, including sexual health. Excess weight and obesity can contribute to a variety of health issues, including ED. By incorporating Ultra CBD gummies into a weight management plan, individuals may be able to address multiple factors contributing to their ED and improve their overall quality of life.
Ultra CBD gummies are a convenient and discreet way to incorporate CBD into your daily routine. These gummies are easy to take on the go and can be a practical addition to a busy lifestyle. Additionally, Ultra CBD gummies come in a variety of flavors, making them a tasty and enjoyable way to support your weight management goals.
When used in conjunction with a healthy diet and regular exercise, Ultra CBD gummies may help individuals achieve and maintain a healthy weight. By reducing inflammation in the body and promoting overall wellness, these gummies can support weight loss efforts and improve sexual health in the process.
How to Incorporate Ultra CBD Gummies into Your Routine
When incorporating Ultra CBD gummies into a weight management plan, it is important to start slowly and gradually increase your dosage as needed. Begin by taking one gummy per day and monitor how your body responds. If you do not notice any changes, you may consider increasing your dosage to two gummies per day.
It is also important to be consistent with your use of Ultra CBD gummies. Taking them at the same time each day can help you establish a routine and maximize their potential benefits. Additionally, be sure to follow the recommended dosage guidelines provided by the manufacturer to ensure safe and effective use of the product.
As with any supplement, it is important to listen to your body and pay attention to how you feel when taking Ultra CBD gummies. If you experience any negative side effects or discomfort, discontinue use and consult with a healthcare provider. Remember that CBD affects everyone differently, so what works for one person may not work for another.
Conclusion
Overall, Ultra CBD gummies have the potential to be a valuable addition to a comprehensive weight management plan for individuals with ED. By addressing underlying issues such as stress, anxiety, and poor circulation, these gummies may help improve sexual health and overall well-being. As with any supplement, it is important to consult with a healthcare provider before incorporating Ultra CBD gummies into your routine to ensure safe and effective use.
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