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Eli Lilly announced promising clinical trial results for orforglipron, a daily pill that could rival the effectiveness of injectable GLP-1 drugs like Ozempic and Mounjaro for type 2 diabetes and weight loss. This new oral medication demonstrated similar reductions in blood sugar and comparable weight loss to the injectables in a 40-week study. Unlike existing GLP-1s that require refrigeration and injection, orforglipron offers the convenience of a pill, potentially increasing its accessibility. While Eli Lilly anticipates seeking regulatory approval soon and analysts predict it will be a blockbuster, the drug's pricing and global accessibility remain key questions. The development of this non-peptide oral GLP-1 represents a significant advancement in pharmaceutical chemistry and could transform treatment options for millions.

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