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(USMLE topics) Methamphetamine: mechanism of action, short-term and long-term effects, addiction and overdose. Purchase a license to download a non-watermarked copy of this video on AlilaMedicalMedia(dot)com ©Alila Medical Media. All rights reserved. Voice by: Ashley Fleming All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition. Methamphetamine, also called meth or crystal meth, among other names, is a psychostimulant drug mainly known for its recreational use. Methamphetamine is chemically similar to amphetamine, a drug used to treat attention-deficit hyperactivity disorder, obesity and narcolepsy; but being more potent and highly addictive, methamphetamine is rarely prescribed for medical treatments. Most commonly, the drug is produced illegally, from pseudoephedrine, an ingredient in cold medicines. It can exist as white powder, pills, or bluish-white crystals, and can be consumed by swallowing, smoking, snorting, or injecting. Methamphetamine acts to increase the amount of a neurotransmitter called dopamine in the brain. Dopamine is at the basis of the brain reward pathway, which is designed to “reward” the body for important behaviors that are essential for survival, such as feeding when hungry. Engaging in enjoyable activities causes dopamine release from dopamine-producing neurons into a space between neurons, where it binds to and stimulates its receptors on the neighboring neuron. This stimulation is believed to produce pleasurable feelings or rewarding effect. Normally, dopamine molecules are promptly cleared from the synaptic space to ensure that the postsynaptic neurons are not over-stimulated. This is possible thanks to the action of dopamine-transporter, which channels dopamine back to the transmitting neuron. Methamphetamine binds to dopamine-transporter and blocks dopamine re-uptake. In addition, it can enter the transmitting neuron and trigger more dopamine release. The result is that dopamine builds-up in the synapse to a much greater amount than normal. This produces a continuous over-stimulation of receiving neurons and is responsible for the prolonged and intense euphoria experienced by drug users. At a low dose, methamphetamine stimulates the brain and can elevate mood and alertness; and by accelerating heart rate and breathing rate, it increases energy in fatigued individuals. It also reduces appetite and promotes weight loss. These seemingly “positive” effects keep users coming back for more, eventually leading to addiction and potential overdose. Long-term drug users may experience extreme weight loss, severe dental damage, and constant hyperactivity which results in anxiety, sleeping disorders and violent behaviors. Overdose takes the drug’s effects to the extreme and can cause psychosis, heart attacks, seizures, strokes, organ failures, and even death. Currently, there is no approved pharmacological treatment for methamphetamine addiction; the most effective treatments are cognitive behavioral therapies.

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The struggle to lose weight is a common challenge faced by many individuals looking to improve their health and wellness. With so many fad diets and weight loss supplements on the market, it can be overwhelming to find a safe and effective solution that fits your lifestyle. Thankfully, Leannx Keto Gummies offer a natural and convenient way to support your weight loss goals.

What are Leannx Gummies?

Leannx Gummies are a specially formulated dietary supplement that combines the power of keto with the delicious taste of gummies. These gummies are infused with exogenous ketones, which are known for their ability to support the body’s natural ketosis process. By taking Leannx Gummies regularly, you can help your body burn fat more efficiently and reach your weight loss goals faster.

Unlike many weight loss supplements on the market, Leannx Gummies are made with all-natural ingredients that are free from harmful chemicals and additives. This means you can feel confident in the quality and safety of the product you are putting into your body. Plus, with their convenient gummy form, you can easily incorporate Leannx Gummies into your daily routine without any hassle.

How do Leannx Gummies work?

Leannx Gummies work by providing your body with a source of exogenous ketones, which can help kickstart the natural ketosis process. Ketosis is a metabolic state in which your body burns fat for energy instead of carbohydrates. By supplementing with exogenous ketones, you can help your body enter and maintain ketosis more effectively, leading to increased fat burning and weight loss.

In addition to supporting ketosis, Leannx Gummies are also rich in antioxidants and other essential nutrients that can help boost your overall health and well-being. These gummies can help improve your energy levels, enhance mental clarity, and reduce inflammation in the body. By taking Leannx Gummies regularly, you can enjoy a wide range of health benefits in addition to supporting your weight loss goals.

Why choose Leannx Gummies?

There are many weight loss supplements on the market, so why choose Leannx Gummies? The answer is simple – Leannx Gummies offer a safe, natural, and effective way to support your weight loss journey. These gummies are made with high-quality ingredients that are backed by scientific research and formulated to deliver real results. Plus, with their delicious taste and convenient gummy form, taking Leannx Gummies is a pleasant experience that you can look forward to each day.

Furthermore, Leannx Gummies are manufactured in a GMP-certified facility in the USA, ensuring the highest standards of quality and safety. This means you can trust that you are getting a premium product that is free from harmful contaminants and meets strict regulatory guidelines. With Leannx Gummies, you can feel confident in the integrity of the product you are using to support your weight loss goals.

Where can I buy Leannx Gummies?

If you are ready to lean into weight loss with Leannx Keto Gummies, you can purchase them directly from the official Leannx website. This ensures that you are getting a genuine product that is backed by a money-back guarantee. Simply visit the official website, place your order, and start your journey towards a healthier, happier you with Leannx Gummies.

Are Leannx Gummies right for me?

Leannx Gummies are designed for individuals who are looking to support their weight loss goals in a safe and natural way. Whether you are following a keto diet or simply looking for a boost in your weight loss journey, Leannx Gummies can help you reach your goals more effectively. However, it is always recommended to consult with your healthcare provider before starting any new dietary supplement to ensure that it is right for you.

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With their delicious taste, convenient form, and powerful formula, Leannx Gummies are a great choice for anyone looking to lean into weight loss and improve their overall health and wellness. Give Leannx Gummies a try today and see the difference they can make in your weight loss journey.

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If you've ever felt like you're failing your diet before you've even finished your morning coffee... this one's for you. Most people don’t need more willpower—they need a better setup. Because when life is draining your mental battery before 9am, expecting yourself to have monk-like discipline by dinner is... optimistic, at best. In this video, we explore why willpower keeps letting you down and what actually makes consistency easier—especially if you're juggling kids, work, and the chaos of real life. Spoiler: it’s not about being “more motivated.” If you’ve ever found yourself staring into your fridge at 6pm thinking, “screw it,” watch this before you blame yourself again. Need some help losing weight? Head to fatlossfundamentals.co.uk

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You’re doing everything right — training hard, eating clean, grinding every day… and still feel stuck. What gives? Here’s the truth: Your body isn’t broken, but it might be burned out. And if you’re constantly pushing harder without refueling, your body’s hitting survival mode. In this video, I break down: ✅ Why more cardio and fewer calories are keeping you stuck ✅ How to train smarter (not harder) to finally break through ✅ The 3 key steps to reset your metabolism and start burning fat again If you’re tired of spinning your wheels and ready to make real progress, this one’s for you. 📩 Apply for Kettlebell Kuts Coaching: https://precisionkettlebells.com/transformation-application 🔔 Subscribe for weekly fat loss tips, kettlebell workouts, and mindset shifts that actually work.

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Looking for More Muscle and Less Fat? The Research shows that you actually need to eat more - seriously. Check out the video. Check out more Naked Nutrition TV videos at http://www.nakednutritionnetwork.com

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