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In this episode, we talk about WeightWatchers' purchase of a telehealth company and adding Weight Loss Medication with GLP-!s like Wegovy and Zepbound to their Program for more sustainable weight loss. We also discuss the importance of seeing Obesity as a disease.

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When we eat a meal containing carbohydrates a peptide called GLP-1 is released into the blood and acts in several ways to improve glucose regulation. It stimulates insulin release from the pancreas, increases insulin sensitivity, and suppresses appetite. A peptide called exenatide originally discovered in the venom of the Gila monster activates GLP-1 receptors and is now prescribed as a treatment for diabetes and obesity. Preclinical studies at the NIH showed that exenatide prevents neuronal damage and improves functional outcome in experimental models of Parkinson’s and Alzheimer’s diseases. Professor Tom Foltynie at University College London then led clinical trials of exenatide in Parkinson’s disease which demonstrated beneficial effects of exenatide. In this episode I talk with Professor Foltynie about GLP1 receptor agonists and how they protect neurons against damage and dysfunction in Parkinson’s and other neurological disorders. LINKS Professor Foltynie’s webpage: https://www.ucl.ac.uk/ion/research/our-departments/clinical-and-movement-neurosciences/people/prof-t-foltynie Lancet article: RCT of Exenatide in Parkinson’s disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831666/pdf/nihms939356.pdf Review articles on GLP1 and its effects on diabetes and obesity https://www.cell.com/action/showPdf?pii=S1550-4131%2818%2930179-7 Review article on energy metabolism and Parkinson’s disease: https://content.iospress.com/download/journal-of-parkinsons-disease/jpd130335?id=journal-of-parkinsons-disease%2Fjpd130335 Preclinical studies of Exenatide for: Parkinson’s disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633544/pdf/zpq1285.pdf Alzheimer’s disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948479/ Huntington’s disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628604/pdf/318.pdf

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Witness a personal weight loss journey after using a medication. This individual highlights changes to their body shape, showcasing the potential effects of the treatment. The video may offer inspiration or insights for those exploring weight management options.#weightlossjourney #transformation #healthylifestyle #wellness #bodypositivity

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🔥 Lose Fat in Seconds! 😂 (Not Clickbait… kinda 😆) Tired of long workouts? Well, here’s the ultimate instant fat loss trick… 😜 Watch till the end for the secret! 👉 Don’t forget to LIKE 👍, SUBSCRIBE 🔔, and COMMENT if you’ve ever tried this "method"! 😂 #LoseFatFast #FitnessHack #FunnyShorts

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