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HENDERSON, NV – PatchMD, a leading innovator in transdermal nutrient delivery, is excited to announce the launch of its new GLP-1 Support Patch Collection—a targeted solution designed to complement individuals using GLP-1 receptor agonist medications such as Ozempic, Wegovy, and Mounjaro for weight management. This new collection is available now at www.patchmd.com/glp-1-patches.html. GLP-1 receptor agonists are transforming the landscape of medical weight loss, yet many individuals experience nutrient deficiencies and side effects such as nausea and appetite suppression. PatchMD’s topical patches provide an innovative way to supplement essential vitamins, minerals, and other nutrients without the need for pills or powders—ensuring optimal absorption and convenience. Why PatchMD’s GLP-1 Patches? Unlike traditional oral supplements that pass through the digestive system, PatchMD’s GLP-1 patches deliver nutrients directly through the skin, bypassing potential gastrointestinal discomfort and absorption issues. This makes them an ideal choice for individuals experiencing nausea, reduced appetite, or other side effects commonly associated with GLP-1 medications. PatchMD’s GLP-1 Support Collection includes: - Essential Nutrient Support – Formulated to replenish key vitamins and minerals for overall well-being. - Nausea Relief Patch – Designed to help manage nausea, a common side effect of GLP-1 medications. - Appetite Suppression Patch – Supports metabolic health and appetite control in a natural, balanced way. - Metabolism Plus Patch – Provides additional energy and metabolic support to complement weight management. The Latest in GLP-1 Research & Innovation As a trusted name in transdermal supplementation, PatchMD remains at the forefront of scientific advancements in weight management support. We recently published detailed insights on two next-generation GLP-1 medications, providing valuable information for individuals seeking the latest updates in the field: - Mazdutide: A Next-Gen GLP-1 Therapy – Learn about this novel GLP-1/GIP dual agonist and its potential benefits: www.patchmd.com/mazdutide.html. - CagriSema: The Future of Weight Loss Medications – A deep dive into CagriSema and how it compares to existing treatments: www.patchmd.com/what-is-cagrisema.html. About PatchMD PatchMD is a leader in transdermal supplement technology, offering a variety of vitamin patches that bypass the digestive system for superior absorption. Our patches are lactose-free, gluten-free, and non-GMO, making them an excellent option for those with dietary restrictions. By providing an easy, effective, and hassle-free way to get essential nutrients, PatchMD empowers individuals to take charge of their health with science-backed supplementation. For more information about PatchMD’s GLP-1 Support Patches, visit www.patchmd.com. Source: https://thenewsfront.com/patchmd-introduces-new-glp-1-support-patches-for-individuals-on-weight-loss-medications/
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Obesity is a growing epidemic worldwide, with nearly 40% of adults and 18% of children and adolescents classified as obese. This chronic condition can lead to a myriad of health issues, including heart disease, type 2 diabetes, and certain types of cancer. Despite the availability of various diets, exercise regimens, and weight loss medications, many individuals struggle to achieve sustainable weight loss. However, recent advancements in medical science have shown promise in the form of semaglutide, a medication originally used to treat type 2 diabetes that has shown significant potential in promoting long-term weight loss.
The Science Behind Semaglutide
Semaglutide belongs to a class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists. These drugs work by mimicking the effects of a naturally occurring hormone in the body that regulates blood sugar levels and satiety. By activating GLP-1 receptors in the brain, semaglutide helps to reduce appetite, increase feelings of fullness, and slow down stomach emptying. In addition to its effects on weight loss, semaglutide has also been shown to improve blood sugar control and reduce the risk of cardiovascular events in patients with type 2 diabetes.
One of the key advantages of semaglutide over other weight loss medications is its long-acting nature. Unlike some drugs that require multiple doses throughout the day, semaglutide is administered once weekly via injection. This convenience not only improves adherence to treatment but also helps to maintain steady levels of the medication in the body, leading to more consistent weight loss results.
Benefits of Long-Term Semaglutide Use
Studies have demonstrated that individuals who use semaglutide for an extended period can achieve significant and sustainable weight loss. In one clinical trial, participants who took semaglutide for 68 weeks lost an average of 15% of their body weight, compared to just 2.4% in the placebo group. This weight loss was maintained over a 5-year follow-up period, highlighting the long-term efficacy of semaglutide in helping individuals achieve and maintain a healthier weight.
In addition to weight loss, long-term use of semaglutide has been associated with improvements in other health markers, such as blood pressure, cholesterol levels, and markers of inflammation. These benefits not only reduce the risk of developing obesity-related comorbidities but also improve overall quality of life for individuals struggling with excess weight.
Potential Side Effects and Considerations
While semaglutide offers significant benefits in terms of weight loss and metabolic health, it is not without potential side effects. Common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation. These gastrointestinal symptoms typically improve over time as the body adjusts to the medication. In rare cases, more serious side effects such as pancreatitis or thyroid tumors may occur, so it is important for individuals considering semaglutide for weight loss to discuss the risks and benefits with their healthcare provider.
Another consideration when using semaglutide for long-term weight loss is the cost of the medication. Semaglutide is a prescription medication that may not be covered by all insurance plans, making it inaccessible for some individuals. However, many pharmaceutical companies offer patient assistance programs or discounts to help offset the cost of the medication for those who need it.
Conclusion
In conclusion, the long-term use of semaglutide has shown promise in promoting sustainable weight loss and improving overall health outcomes for individuals struggling with obesity. By harnessing the power of GLP-1 receptors, semaglutide helps to reduce appetite, increase feelings of fullness, and promote steady weight loss over time. While potential side effects and cost considerations should be taken into account, the benefits of semaglutide in terms of weight loss, metabolic health, and quality of life make it a valuable tool in the fight against obesity.
For more information on semaglutide and its use for weight loss, consult with your healthcare provider to determine if this medication is right for you.
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The video version of this podcast can be found here: https://youtu.be/W0LL-1BwV3w?si=OT-GNCXaHoA7dcbs This podcast makes reference to guidelines produced by the "National Institute for Health and Care Excellence" in the UK, also referred to as "NICE". Please note that the content on this channel reflects my professional interpretation/summary of the guidance and that I am in no way affiliated with, employed by or funded/sponsored by NICE. My name is Fernando Florido and I am a General Practitioner in the United Kingdom. In this video I will go through a National Patient Safety Alert released on 3.1.2024 by the Department of Health and NHS England on the shortage of GLP1 receptor agonists, touching on sections of the NICE guideline on type 2 diabetes as well as relevant pharmaceutical information, always focusing on what is relevant in Primary Care only. I am not giving medical advice; this video is intended for health care professionals; it is only my summary and my interpretation of the guidelines and you must use your clinical judgement. There is a podcast version of this and other videos that you can access here: Primary Care guidelines podcast: · Redcircle: https://redcircle.com/shows/primary-care-guidelines · Spotify: https://open.spotify.com/show/5BmqS0Ol16oQ7Kr1WYzupK · Apple podcasts: https://podcasts.apple.com/gb/podcast/primary-care-guidelines/id1608821148 There is a YouTube version of this and other videos that you can access here: • The Practical GP YouTube Channel: https://youtube.com/@practicalgp?si=ecJGF5QCuMLQ6hrk The PDF document related to the safety alert on GLP- RA shortage can be found here: · https://www.cas.mhra.gov.uk/ViewandAcknowledgment/ViewAttachment.aspx?Attachment_id=104161 The safety alert on GLP- RA shortage can be found here: · https://www.cas.mhra.gov.uk/ViewandAcknowledgment/ViewAlert.aspx?AlertID=103245 The Central Alerting System Homepage can be found here: · https://www.cas.mhra.gov.uk/Home.aspx Intro / outro music: Track: Halfway Through — Broke In Summer [Audio Library Release] • Music provided by Audio Library Plus • Watch: https://youtu.be/aBGk6aJM3IU (https://www.youtube.com/watch?t=0s&v=aBGk6aJM3IU) • Free Download / Stream: https://alplus.io/halfway-through (https://www.youtube.com/redirect?event=video_description&q=https%3A%2F%2Falplus.io%2Fhalfway-through&redir_token=QUFFLUhqbVNpZlBNM0lCeDIxQzRkU29qUnJGQy15WEtTQXxBQ3Jtc0tuUUFSMkZwSEVuaHdUTWlYV21fZmpjWS1WRXI3R0hZU056MkpmRFpKdXdGYm1La3BlazhUemZ5SkVMTFdaWWRvSG9Ucy1neWpudTJ0MUIxNnl2NmhvR0lmdzduWXEwUUg0alduYkRNdjlWWTNsMnhzaw&v=aBGk6aJM3IU) Transcript If you are listening to this podcast on YouTube, for a better experience, switch to the video version. The link is in the top right corner of the video and in the episode description. Hello and welcome, I am Fernando, a GP in the UK. In this episode I will go through a National Patient Safety Alert released on 3.1.2023 by the Department of Health and NHS England on the shortage of GLP1 receptor agonists, touching on sections of the NICE guideline on type 2 diabetes as well as relevant pharmaceutical information, always focusing on what is relevant in Primary Care only. If you want to access the safety alert website or the associated PDF document, the link is in the episode description. Right, let’s jump into it. You are probably aware that the supply of GLP-1 receptor agonists continues to be limited, with supplies not expected to return to normal until at least the end of 2024. The supply issues have been caused by an increase in demand for these products for licensed and off-label indications. The situation at the moment is that exenatide as Byetta® will be discontinued in March 2024. In addition, liraglutide as Victoza® continues to be out of stock and further stock is not expected until end of 2024. The supply of other agents such as injectable semaglutide as Ozempic® and Dulaglutide as Trulicity® may be unreliable and the shortages may cause significant issues. So, what is the solution? Well, oral semaglutide has come to the rescue. Semaglutide as Rybelsus® tablets are now available in sufficient quantities to support initiation of GLP-1 RA for type 2 diabetes in line with NICE guidance. So let’s remind ourselves of what NICE recommends for type 2 diabetes. NICE says that if triple therapy with metformin and 2 other oral drugs is not effective, not tolerated or contraindicated, we can consider triple therapy by switching one drug for a GLP‑1 receptor agonist if: · The BMI is 35 or higher and there are psychological or medical problems associated with obesity. We will adjust the BMI to 32.5 for people from Black, Asian and other minority ethnic groups or · For lower BMIs if: o insulin would have occupational implications or o weight loss would benefit other significant comorbidities. NICE also says that we should only ...
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