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Why is metformin being used in patients without diabetes who are on antipsychotics like olanzapine or risperidone? In this episode, we break down the new clinical guidelines on how and when to use metformin to prevent or treat weight gain caused by antipsychotic medications. Check out the video here! https://www.youtube.com/watch?v=pdDwtZFzwmA 👂 Have you seen metformin used this way? Drop your experience in the comments—let's learn from each other. 📚 References: Carolan A, Hynes-Ryan C, Agarwal SM, et al. Metformin for the prevention of antipsychotic-induced weight gain: guideline development and consensus validation. Schizophr Bull. 2024; Published online Dec 9, 2024. PsychiatryOnline. Metformin can be used to prevent or treat antipsychotic-induced weight gain. https://psychiatryonline.org/doi/10.1176/appi.pn.2025.02.2.8 American Psychiatric Association (APA). Practice Guideline for the Treatment of Patients With Schizophrenia. Aoife Carolan, Caroline Hynes-Ryan, Sri Mahavir Agarwal, Rita Bourke, Walter Cullen, Fiona Gaughran, Margaret K Hahn, Amir Krivoy, John Lally, Stefan Leucht, John Lyne, Robert A McCutcheon, Michael J Norton, Karen O’Connor, Benjamin I Perry, Toby Pillinger, David Shiers, Dan Siskind, Andrew Thompson, Donal O’Shea, Dolores Keating, Brian O’Donoghue, Metformin for the Prevention of Antipsychotic-Induced Weight Gain: Guideline Development and Consensus Validation, Schizophrenia Bulletin, 2024;, sbae205, https://doi.org/10.1093/schbul/sbae205 ⚠️ Important Note: This video is for educational purposes only and does not replace professional medical advice. Always consult a healthcare provider before starting or changing medications. 📢 Disclaimer: The images used in this video are for educational/informational purposes only and belong to their respective owners. No copyright infringement is intended. ============================================================ #Metformin #Antipsychotics #WeightGain #PharmacyEducation #PharmacistLife #MentalHealthMedications #SchizophreniaTreatment #BipolarDisorder #Clozapine #Olanzapine #Quetiapine #Risperidone Metformin for antipsychotic-induced weight gain, metformin and antipsychotics, metformin weight gain prevention, metformin schizophrenia, metformin bipolar disorder, metformin olanzapine, metformin quetiapine, metformin risperidone, metformin clozapine, antipsychotic weight gain treatment, metformin guidelines 2024, metformin dosing for weight gain, metformin side effects, metformin and GLP-1 agonists, metformin and lifestyle changes, metformin for adolescents on antipsychotics, metformin and metabolic syndrome, off-label use of metformin, metformin and psychiatric medications, metformin and insulin resistance, metformin and appetite suppression
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Semaglutide is a medication that has been gaining attention for its potential use in weight loss. Originally approved as a once-weekly injection for type 2 diabetes, studies have shown that when given at a higher dose, semaglutide can lead to significant weight loss in people with obesity. This has led to the development of semaglutide as a weight loss medication, with a once-weekly injection specifically formulated for this purpose. But how exactly should semaglutide be dosed for weight loss? In this article, we will explore the guidelines and considerations for semaglutide dosage in the context of weight loss.
Proper Dosage Guidelines
When it comes to dosing semaglutide for weight loss, it is important to follow the recommendations provided by healthcare professionals. Typically, the starting dose for semaglutide for weight loss is lower than the dose used for type 2 diabetes. The recommended starting dose is usually around 0.25 mg once weekly, with the option to increase the dose gradually over time. Healthcare providers will monitor weight loss progress and adjust the dosage as needed to achieve the desired outcomes.
In addition to the recommended starting dose, it is essential to consider the individual patient’s characteristics when determining the appropriate dosage of semaglutide for weight loss. Factors such as age, weight, medical history, and other medications being taken can all influence the optimal dose of semaglutide. Healthcare providers will take these factors into account when prescribing the medication and make adjustments as necessary based on the individual’s response to treatment.
One important consideration when dosing semaglutide for weight loss is the potential for side effects. Like any medication, semaglutide can cause adverse reactions in some individuals, such as nausea, vomiting, diarrhea, and abdominal pain. These side effects can vary in severity and may impact the individual’s ability to tolerate the medication. Healthcare providers will closely monitor patients for side effects and may need to adjust the dosage or schedule of administration to minimize these effects.
Monitoring and Adjusting Dosage
Monitoring is a crucial aspect of dosing semaglutide for weight loss. Healthcare providers will regularly assess the patient’s weight, overall health, and response to treatment to determine if the current dosage is effective. If weight loss is not occurring as expected or if the patient is experiencing significant side effects, adjustments to the dosage may be necessary. In some cases, healthcare providers may need to increase the dose to achieve better results, while in others, they may need to decrease the dose to improve tolerability.
It is essential for patients taking semaglutide for weight loss to communicate openly with their healthcare providers about their treatment experience. Reporting any changes in weight, side effects, or other concerns can help healthcare providers make informed decisions about adjusting the dosage of semaglutide. Patients should not attempt to change the dosage or frequency of administration on their own without consulting their healthcare provider, as this can impact the safety and effectiveness of the treatment.
Combining Semaglutide with Lifestyle Changes
While semaglutide can be an effective tool for weight loss, it is not a standalone solution. To achieve the best results, it is essential to combine semaglutide treatment with lifestyle changes such as diet modification and increased physical activity. Healthcare providers will work with patients to develop a comprehensive weight loss plan that incorporates semaglutide therapy alongside healthy lifestyle habits. This multifaceted approach can enhance the effectiveness of semaglutide and support long-term weight management.
Patients should be prepared to make changes to their diet and exercise habits when starting semaglutide for weight loss. Healthcare providers may recommend a specific meal plan, calorie intake target, or exercise routine to complement the effects of semaglutide. By following these recommendations and staying consistent with treatment, patients can maximize the benefits of semaglutide and improve their chances of successful weight loss.
Conclusion
In conclusion, proper dosing of semaglutide for weight loss involves starting at a lower dose and gradually increasing as needed, considering individual patient characteristics, monitoring for side effects, and adjusting the dosage based on response to treatment. Healthcare providers play a crucial role in guiding patients through the dosing process and ensuring that semaglutide is used safely and effectively for weight loss. By combining semaglutide treatment with lifestyle changes, patients can optimize their weight loss results and improve their overall health and well-being.
It is essential for patients considering semaglutide for weight loss to consult with their healthcare providers to determine the most appropriate dosage and treatment plan for their individual needs. Open communication, regular monitoring, and a commitment to healthy habits can help ensure the success of semaglutide therapy for weight loss.
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Top 10 Common Side Effects of Metformin (And How to Handle Them) If you're taking metformin for type 2 diabetes, you're not alone — it’s one of the most prescribed medications worldwide. While it’s incredibly effective at lowering blood sugar and improving insulin sensitivity, metformin can come with a few side effects, especially when you're just starting out. Wondering what to expect? Here are the 10 most common side effects of metformin, plus tips to manage them like a pro. 1. Nausea Feeling queasy after taking metformin? You’re not alone. Nausea is super common, especially when starting treatment. 👉 Quick Fix: Always take it with food, and start with a low dose. 2. Diarrhea Metformin can speed up digestion, sometimes a little too much. 💡 Pro Tip: Ask your doctor about switching to extended-release metformin (XR) if diarrhea doesn’t ease up. 3. Stomach Cramps & Bloating That gassy, crampy feeling? Totally normal at first. 🍽️ Fix it fast: Avoid greasy or spicy foods and eat smaller meals. 4. Metallic Taste A weird, bitter taste in your mouth after taking metformin? Yep, it’s a thing. 😬 Solution: Stay hydrated, chew sugar-free gum, or suck on mints. 5. Loss of Appetite Metformin can help reduce appetite — sometimes too well. 📉 What to watch for: If you’re losing too much weight or skipping meals often, talk to your doctor. 6. Vitamin B12 Deficiency (Long-Term) Over time, metformin can lower your B12 levels — which can cause fatigue, nerve issues, and memory problems. 🧪 Simple solution: Get regular blood tests and supplement if needed. 7. Headaches New to metformin and feeling a little headachy? 💧 Try this: Stay hydrated, eat regularly, and monitor your blood sugar. 8. Fatigue or Weakness Low energy on metformin? Could be due to B12 deficiency, low blood sugar, or digestive issues. 💬 Check in: If it lasts more than a few days, ask your doctor to run some tests. 9. Lactic Acidosis (Rare but Serious) This is very rare — but serious. Know the warning signs: deep breathing, muscle pain, confusion, and extreme fatigue. 🚨 Act fast: Seek emergency help if you notice these symptoms, especially if you have kidney issues or drink heavily. 10. Low Blood Sugar (When Combined with Other Meds) Metformin alone usually won’t drop your blood sugar too low — but when combined with insulin or other diabetes meds, it can. 🍬 Keep safe: Monitor blood sugar and carry a quick source of glucose just in case. When to Call Your Doctor Don’t tough it out — contact your provider if you experience: Persistent nausea, diarrhea, or fatigue Tingling in hands or feet Memory issues Symptoms of lactic acidosis How to Make Metformin Easier on Your Body ✔️ Take it with food ✔️ Start low, go slow ✔️ Try extended-release if needed ✔️ Stay hydrated and avoid alcohol ✔️ Monitor B12 levels Final Thoughts Metformin is a game-changer in managing type 2 diabetes — and most side effects are temporary and manageable. The key? Know what to expect, listen to your body, and stay in touch with your healthcare provider. Have you had side effects on metformin? Drop a comment below and share your tips — someone else might really benefit from your experience! Medical disclaimer: Medinaz Academy does not provide medical advice. The content available in our books and videos, on our website, or on our social media handles do not provide a diagnosis or other recommendation for treatment and are not a substitute for the professional judgment of a healthcare professional in diagnosis and treatment of any person or animal. We intend to provide educational information only. The determination of the need for medical services and the types of healthcare to be provided to a patient are decisions that should be made only by a physician or other licensed health care provider. Always seek the advice of a physician or other qualified healthcare provider with any questions you have regarding a medical condition. #shortsfeed #diabetes #metformin #bloodsugar #health #latestnews
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