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Even as we prioritize natural interventions in functional medicine, GLP-1 agonist drugs such as Wegovy and Ozempic offer sometimes life-changing support for those who have long struggled with resistant overweight/obesity and high blood sugar. However, there are side effects, including the risk of substantial muscle loss and sagging, aged skin ("Ozempic face" as it's indelicately known). It's a concern that hits home for me, considering the pivotal role we know that muscle plays in overall health and longevity. In this New Frontiers podcast episode I welcome back Dr. Anurag Singh to unravel the complexities of these issues. We explore the interplay between metabolic health and muscle preservation, touching on everything from the mechanisms of GLP-1 agonists and their long-term effects on aging and sarcopenia, to the promising potential of dietary and lifestyle interventions to counteract negative effects. We consider the potential for one of my all-time fave postbiotic epinutrients - Urolithin A - to assist by supporting mitochondrial health and preserving/enhancing muscle quality. This timely conversation is one you won't want to miss. Tune in and please leave us a review wherever you listen to New Frontiers. – DrKF Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for all the relevant links and resources. *Guest information* Anurag Singh, MD, PhD Chief Medical Officer at Timeline *Thank you to our sponsor* Timeline: https://tinyurl.com/4npjcvjf Mitopure: https://tinyurl.com/ypfjws2e Research from Timeline: https://tinyurl.com/53p6yjc9 [email protected] *Timeline Discount for New Frontiers Listeners* Timeline is offering Dr. Fitzgerald’s readers a 10% discount on Timeline products. Head on over to https://tinyurl.com/ypfjws2e and use the code KARA10 at the checkout. *Show Notes* Study: Once-Weekly Semaglutide in Adults with Overweight or Obesity: https://tinyurl.com/y3c2ypkw Pre-clinical trial (Recruiting): Effects of Urolithin A Supplementation on Glucose Metabolism in Healthy Adults 55= Years Old: A Randomized Triple-Masked Controlled Clinical Trial - https://https://tinyurl.com/bdzfccr8 Study: Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults - https://tinyurl.com/2p9pjpxc Study: Antidiabetic Effect of Urolithin A in Cultured L6 Myotubes and Type 2 Diabetic Model KK-Ay/Ta Mice with Glucose Intolerance - https://tinyurl.com/2jkhmu9w Study: Urolithin A, a Gut Metabolite, Improves Insulin Sensitivity Through Augmentation of Mitochondrial Function and Biogenesis - https://tinyurl.com/mvrjxxsm Study: Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults A Randomized Clinical Trial - https://tinyurl.com/fscfdd85 Study: The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans - https://tinyurl.com/mr2hd4ms Study: Direct supplementation with Urolithin A overcomes limitations of dietary exposure and gut microbiome variability in healthy adults to achieve consistent levels across the population - https://tinyurl.com/e6npdvyp Preprint article: Topical application of Urolithin A slows intrinsic skin aging and protects from UVB-mediated photodamage: Findings from Randomized Clinical Trials - https://tinyurl.com/2m2nzd56 Preclinical trial: Effects of Mitopure (Urolithin A) on Skeletal Muscle Function, Iron Metabolism and Endurance Performance (ENDURO) - https://tinyurl.com/nhkw2pvc Study: The gut microbiota metabolism of pomegranate or walnut ellagitannins yields two urolithin-metabotypes that correlate with cardiometabolic risk biomarkers: Comparison between normoweight, overweight-obesity and metabolic syndrome - PubMed (nih.gov) - https://tinyurl.com/mrkk33e5 Study: Urolithin A exerts antiobesity effects through enhancing adipose tissue thermogenesis in mice | PLOS Biology - https://tinyurl.com/3s38vtau Study: Urolithin A production drives the effects of pomegranate on the gut microbial metabolism of bile acids and cholesterol in mild dyslipidaemic overweight and obese individuals - PubMed (nih.gov) - https://tinyurl.com/wdzk3tx7 *DrKF Resources* FxMed Podcast: Beyond Mitochondrial Health: Can Urolithin A Slow Down Aging? - https://tinyurl.com/svzahswu DrKF Blog: Beyond Beauty: Targeting Skin Longevity with Urolithin A - https://tinyurl.com/5n6zfu9s DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Bio Age Lab Test: https://tinyurl.com/b7bjmfj9 Bio Age Self Assessment Quiz: https://tinyurl.com/4z8f7ucc Younger You Group Program: https://tinyurl.com/4hvusavw Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

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Are love handles holding you back from feeling your best? This workout is here to help you burn fat and sculpt a more defined waist with just 13 moves. A no-equipment routine that will target your side fat while also toning your core. We have 4 phases for our workout today as these phases provides a structured approach for targeting your love handles. This is done by combining strength training, core activation, leg work, and dynamic movements. The first Phase is your Core Activation & Strengthening, designed to engage and strengthen your core and side muscles, primarily targeting your obliques. This will set the tone for engaging your love handles. Phase 2 is Leg and Glute Activation. This is added to activate your lower body. It complements the core work for overall fat loss and muscle shaping. Phase 3 is Dynamic Core and Full-Body Engagement. This provides functional core tone. It will also build stability over time. Last Phase is your Core Finisher & Flexibility. The goal is to maximize the effect, ensuring muscles are fully engaged and fatigued by doing repetitions until the end of the session. With each rep you do, you're one step closer to your dream goals! Goodbye to love handles! Keep working on your routine, it's all about patience and consistency with workouts like this. Soon you'll see the results that you've beein working on. Just keep pushing! Good luck and have fun! ❤️💪 _**Don’t forget to share your experience and progress in the comment section. If you want to be notified when I upload a new video, make sure to subscribe to our channel. I upload new videos everyday from Monday to Saturday!_ ========================================== Stay connected on my other social media platforms so you can share your journey with others and stay motivated! *Instagram:* https://www.instagram.com/robertasgym/ *TikTok:* https://www.tiktok.com/@robertasgym *Reddit:* https://www.reddit.com/user/robertasgym/ *Twitter:* https://x.com/robertasgym *Tumblr:* https://www.tumblr.com/blog/robertasgym *Wordpress:* https://robertasgym.com/ Let’s keep the motivation going! 💪 ========================================== *TIMECODES:* 00:00 Introduction 00:11 Side Plank Pulse Left 00:38 Side Plank Pulse Right 01:06 Rest 01:24 Side Leg Raise Left 01:57 Side Leg Raise Right 02:31 Rest 02:49 Diagonal Abs Left 03:18 Diagonal Abs Right 03:48 Rest 04:06 Side Crunches Left 04:36 Side Crunches Right 05:07 Rest 05:25 Waist Pinchers Left 05:52 Waist Pinchers Right 06:21 Rest 06:39 Step Back Jacks 07:00 Rest 07:18 Knee Stretch Left 08:09 Knee Stretch Right 08:59 Rest 09:17 Thigh Stretch Left 10:08 Thigh Stretch Right 10:58 Rest 11:16 T Plank 12:07 Rest 12:25 Russian Twist 12:45 Rest 13:03 Side Lunge Windmill 13:27 Rest 13:45 Bird Dog 14:35 Rest 14:53 Knee Tuck Crunch 15:24 Rest 15:42 Side Plank Pulse Left 16:09 Side Plank Pulse Right 16:36 Rest 16:54 Side Leg Raise Left 17:28 Side Leg Raise Right 18:02 Rest 18:20 Diagonal Abs Left 18:49 Diagonal Abs Right 19:19 Rest 19:37 Side Crunches Left 20:07 Side Crunches Right 20:37 Rest 20:55 Waist Pinchers Left 21:23 Waist Pinchers Right 21:51 Rest 22:09 Step Back Jacks 22:31 Rest 22:49 Knee Stretch Left 23:40 Knee Stretch Right 24:30 Rest 24:48 Thigh Stretch Left 25:38 Thigh Stretch Right 26:29 Rest 26:47 T Plank 27:37 Rest 27:55 Russian Twist 28:15 Rest 28:33 Side Lunge Windmill 28:58 Rest 29:16 Bird Dog 30:06 Rest 30:24 Knee Tuck Crunch

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Join me as I share my personal journey with Semaglutide for weight loss! From my initial struggles to the amazing progress I’ve made, I’ll walk you through why I believe this medication is worth it. Whether you’re curious about how it works, the results you can expect, or if it’s the right choice for you, this video has you covered. Don’t forget to like, comment, and subscribe for more weight loss tips and real-life updates! Let's stay in touch. https://instagram.com/candidlyclaudia https://vm.tiktok.com/ZMRQW8YPQ/ Thank you so much for watching! Claudia #WeightLossJourney #Semaglutide #wegovy

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In this episode, MC shares her journey of 9 months using the GLP-1 drug mounjaro. What does the future hold for GLP-1 drugs amid shortage concerns? Stay informed about the latest developments in healthcare and their impact on your health. GLP-1 Shortages is an issue we are learning is a continuing problem. While the pharmaceutical companies of these drugs are trying to move forward with manufacturing facilities, the process is moving very slowly. I work in research and understand the regulations around manufacturing these medications. Still, the shortages exist. While the companies reassure the many patients who are finding success that these shortages will soon end, it doesn't seem consistent. Initially, I was frustrated that I had to go down to the low dose again, but at least I was maintaining. I have been able to reaccess the 5mg dose and am hopeful that I will continue to get access. I am grateful I have a team that helps me plan for possible future shortages. While my original plan was to be under 200 lbs by June, I have modified this to be by the end of the summer. Slow and steady wins the race. I discovered that the FDA allows compound pharmacies to help provide a similar product when there are shortages. Some physicians are working with patients who are more at risk for heart disease and are prescribing microdoses of these drugs to be made by the compound pharmacies. Finally, what I deeply became aware of during this process of reflection was that no matter what, the use of this drug is not a fix-all choice. I still need to move my body (try exercise snacks - breaks of 1-3 minutes of getting your heart rate up), increase my muscle density, and improve my food choices. Ultra-processed foods are a leading cause of inflammation in our bodies. Eating smart must become a way of life for me, and I hope you, too, will see this as a way to improve your health and longevity. Join me on this journey of discovering more about the holistic process of building the healthiest life possible. DISCLAIMER. All of the ideas and information shared on my channel are not supported by my employer or endorsed by any company. Nor do I have any affiliates with any of the referrals listed below. Everything on my channel is shared for education and entertainment. Please speak to your doctor. The information here is not intended to replace your medical care nor to be intended for your health care. These are my experiences and what has worked or doesn't work. RESOURCES: www.stroke.org www.strokesupportassoc.org https://www.cdc.gov/stroke/prevention.htm You can contact me at - [email protected] or www.marycatherinegeorge.

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Can Mounjaro cause hair loss? Mounjaro weight loss and Zepbound weight loss. My tips that I believe prevented hair loss on Mounjaro and Zepbound. *Not medical advice, talk to your own healthcare provider My Mounjaro/Zepbound Amazon Necessities Travel Case: https://amzn.to/3WYwfnm Best Deoderant: https://amzn.to/4aVy6Nj Ninja Creami: https://amzn.to/4dXohAZ Favorite Smoothie Blender: https://amzn.to/4bXRVEl Handheld Frother: https://amzn.to/4bDBdKD Smart Body Scale: https://amzn.to/4bILs0A Food Scale: https://amzn.to/3VjbQbg Control Underarm Sweat: https://amzn.to/4aA0IeI Motive Pure Electrolytes: https://amzn.to/3KqI2mM Grass Fed Organic Whey Protein: https://amzn.to/4dS3vTg Favorite Protein Bars: YUM https://amzn.to/3V3VfXX Mini Beef Sticks: https://amzn.to/3WWLVHT Gin Gin Ginger Chews: https://amzn.to/4dW8PVH Collagen Peptides: https://amzn.to/3WPOtHK Hair Towel Wrap: https://amzn.to/3QT62Tk Hair Brush: Boar Bristle: https://amzn.to/4bJC9gg Hair Brush: https://amzn.to/3wKC3WO Silk Pillowcase: Primary: https://amzn.to/3yvrGXD Travel: https://amzn.to/4boqxQ0 Innersense: https://amzn.to/4c5cqzh Travel Case: https://amzn.to/3WYwfnm #mounjaro #zepbound #weightloss #mounjarojourney #mounjaroweightloss #tirzepatide

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