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GLP-1 agonists are a class of medications that everyone is talking about right now because of their beneficial effects on weight loss. And while they are effective at helping with weight loss, there have been multiple studies that suggest that there is a link between their use and the new onset of thyroid cancer. Let's talk about this connection in more detail to see if it is something you should actually worry about. First off, where does this information come from? Studies like this one (https://pubmed.ncbi.nlm.nih.gov/36356111/) suggest that there is indeed a real risk of thyroid cancer with long term use of GLP-1 agonists in diabetes. This study showed that there were about 2,500 new cases of thyroid cancer in a sample size of over 3.7 million. The incidence of thyroid cancer in these patients was small but still real. It's important to note here that correlation does not equal causation but this is just adding to the pile of studies that suggest a link between these medications and thyroid cancer so it's definitely something that should be thought about prior to using them. Given this information, is it still worth taking medications like Wegovy, semaglutide, saxenda, and victoza? In some situations, it may make sense but my recommendation is to always try to lose weight with diet and exercise first. If you are going to use these medications then do your best to use them in the short term for no more than 1 year. This will minimize the negative side effects while maximizing their benefits. My personal recommendation would still be to try other treatments like bioidentical hormone replacement therapy prior to using GLP-1 agonists. #weightloss #glp1 #weight #weightlosstips #obesity #thyroidcancer #thyroid Download my free thyroid resources here (including hypothyroid symptoms checklist, the complete list of thyroid lab tests + optimal ranges, foods you should avoid if you have thyroid disease, and more): https://www.restartmed.com/start-here/ Recommended thyroid supplements to enhance thyroid function: - Supplements that everyone with hypothyroidism needs: https://bit.ly/3tekPej - Supplement bundle to help reverse Hashimoto's: https://bit.ly/3gSY9eJ - Supplements for those without a thyroid and for those after RAI: https://bit.ly/3tb36nZ - Supplements for active hyperthyroidism: https://bit.ly/3t70yHo See ALL of my specialized supplements including protein powders, thyroid supplements, and weight loss products here: https://www.restartmed.com/shop/ Want more from my blog? I have more than 400+ well-researched blog posts on thyroid management, hormone balancing, weight loss, and more. See all blog posts here: https://www.restartmed.com/blog/ Prefer to listen via podcast? Download all of my podcast episodes here: https://apple.co/3kNYTCS Disclaimer: Dr. Westin Childs received his Doctor of Osteopathic Medicine from Rocky Vista University College of Osteopathic medicine in 2013. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Childs is no longer practicing medicine and does not hold an active medical license so he can focus on helping people through videos, blog posts, research, and supplement formulation. To read more about why he is no longer licensed please see this page: https://www.restartmed.com/what-happened-to-my-medical-license/ This video is for general informational, educational, and entertainment purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Childs and you. You should not make any changes to your medications or health regimens without first consulting a physician. If you have any questions please consult with your current primary care provider. Restart Medical LLC and Dr. Westin Childs are not liable or responsible for any advice, course of treatment, diagnosis, or any other information, services, or product you obtain through this website or video. #thyroid #hypothyroidism #hashimoto's

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Obesity is a major health concern that affects millions of people around the world. It is associated with numerous health risks, including heart disease, diabetes, and certain types of cancer. Despite efforts to combat obesity, many individuals struggle to lose weight and maintain a healthy lifestyle. In recent years, semaglutide has emerged as a promising treatment for obesity, with studies showing that it can lead to significant weight loss in overweight individuals. But why does semaglutide cause weight loss? In this article, we will explore the mechanism behind semaglutide’s weight loss effects.

The Role of Semaglutide in Weight Loss

Semaglutide is a medication that belongs to a class of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists. GLP-1 is a hormone that is produced in the intestine in response to food intake. It plays a key role in regulating blood sugar levels and promoting satiety, or the feeling of fullness. When semaglutide is administered, it mimics the effects of GLP-1 in the body, leading to a number of beneficial effects that can help with weight loss.

One of the primary ways in which semaglutide promotes weight loss is by reducing appetite. GLP-1 has been shown to decrease hunger and increase feelings of fullness, which can help individuals consume fewer calories and lose weight. By activating the GLP-1 receptor in the brain, semaglutide can help regulate food intake and prevent overeating.

In addition to reducing appetite, semaglutide also affects the way the body uses and stores fat. Studies have shown that semaglutide can increase the breakdown of fat cells, leading to a decrease in fat mass. This can result in a reduction in overall body weight and improvements in body composition.

The Impact of Semaglutide on Metabolism

Another way in which semaglutide promotes weight loss is by improving metabolic function. GLP-1 has been shown to increase insulin sensitivity, which can help regulate blood sugar levels and prevent the development of type 2 diabetes. By enhancing insulin action, semaglutide can help individuals better control their blood sugar levels and reduce the risk of weight gain.

Furthermore, semaglutide has been shown to increase energy expenditure, or the number of calories the body burns at rest. This can help individuals achieve a negative energy balance, where they are burning more calories than they consume, leading to weight loss. By boosting metabolism, semaglutide can help individuals achieve their weight loss goals more effectively.

Potential Side Effects of Semaglutide

While semaglutide can be an effective treatment for weight loss, it is important to be aware of potential side effects. Common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation. These side effects are usually mild and tend to improve over time as the body adjusts to the medication.

In rare cases, semaglutide can also cause more serious side effects, such as pancreatitis or thyroid tumors. It is important to speak with a healthcare provider before starting semaglutide to discuss the potential risks and benefits of treatment. Additionally, individuals taking semaglutide should be monitored regularly by a healthcare provider to ensure the medication is safe and effective for them.

Conclusion

In conclusion, semaglutide is a medication that can promote weight loss through a variety of mechanisms. By reducing appetite, increasing fat breakdown, improving metabolic function, and boosting energy expenditure, semaglutide can help individuals achieve their weight loss goals. However, it is important to be aware of potential side effects and to speak with a healthcare provider before starting treatment. With the right approach, semaglutide can be a valuable tool in the fight against obesity and its associated health risks.

Frequently Asked Questions (FAQ)

1. How long does it take to see weight loss results with semaglutide?

It can vary from person to person, but many individuals start to see weight loss results within a few weeks of starting semaglutide treatment.

2. Can semaglutide be used as a long-term weight loss solution?

Semaglutide is currently approved for long-term use in individuals with obesity or overweight who have failed to lose weight through diet and exercise alone.

3. What should I do if I experience side effects while taking semaglutide?

If you experience side effects while taking semaglutide, it is important to speak with your healthcare provider. They can provide guidance on how to manage side effects and determine if the medication is still right for you.