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Your gut bacteria are your secret weight loss tool!! There has been a lot of hype surrounding the new GLP-1 agonist medications ,(Semaglutide, Wegovy, Ozempic, etc) due to their profound impact on weight loss. The reason that these drugs are so effective is due to their ability to stimulate cells within our gut to produce the hormone GLP-1, which is essentially a signal to your body that you are in a "fed state". This signal is detected by the pancreas, causing the release of insulin and the disposal of blood glucose (which is why the drug was initially meant to treat type 2 diabetes, due to the impact on blood glucose specifically). GLP-1 is also able to signal to the brain, which leads to a reduction in gastric emptying, and the slowing of digestion (which is one of the reasons people feel full so quickly on these medications)... The problem with these drugs, however, is the large proportion of people who experience significant side effects (mainly nausea and GI related distress, along with the potential to lose significant muscle mass). The side effect profiles are included in the clinical trial data (SURMOUNT, SURPASS, or SUSTAIN trials). What if I said you can have the same impact on GLP-1, but WITHOUT the drug and therefore without the side effects?!! Well guess what! YOU CAN!.. All you have to do is take care of your gut!! There are many strains and species of healthy bacteria lining our gut, and when we feed them dietary fiber (beans, vegetables, lentils, nuts, seeds, etc), they produce various short-chain fatty acids (butyrate, propionate, acetate). Those then go on to stimulate the gut to produce GLP-1!.. Which has the exact same effect that these pharmaceutical companies are going after!! Simply promoting a healthy gut microbiome with dietary fiber will result in an increase in GLP-1 secretion, and improved metabolic health. Here is a study exactly that (PMID: 29590046). Interested in learning more about the gut, and how it plays a role in our overall health? Tune in to the Kickback Science episode where we talk all about gut health: https://bit.ly/45jpJdf #gut #health #GLP1 #weightloss #metabolism #nutrition #fitness #science #research

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