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Veronica Brady, PhD, FNP-BC of the University of Texas MD Anderson Cancer Center, joined Cancer Nursing Today to discuss her insights on the use of GLP-1 agonists in patients receiving treatment for various types of cancer. “It depends on the cancer that they’re being treated for,” Dr. Brady said. “If they are being treated for a pancreatic cancer, I do not advise use of a GLP-1. If they’re being treated for thyroid cancer, GLP-1s are contraindicated.” Although Dr. Brady did not advise the use of the medication during treatment for pancreatic or thyroid cancer, she highlighted treatment situations in which a GLP-1 could be helpful for patients. “If they are a person that is toward the end of their treatment and they have some concerns about their weight and their blood sugars are elevated, I would try a GLP-1,” she said. “Most definitely.” Dr. Brady explained that while GLP-1 agonists assist with appetite suppression to facilitate weight loss, it’s crucial that patients first adjust their diet to maximize the effectiveness of the medication. “If a person who’s willing to weigh themselves a couple times a week and track that weight loss, [a] GLP-1 in that situation may be feasible,” she said. “But if it’s somebody who is not going to pay attention, [who is] just going to take it because it’s going to decrease [their] appetite, [and] if they’re not eating well already, [then] GLP-1 is not the answer.” Dr. Brady emphasized that patients and their healthcare professionals should also consider the side effects of using a GLP-1 during cancer treatment. “Even if they’re weight-challenged, GLP-1s may not be the answer if they’re not eating well, if they’ve got nausea, [and] vomiting, that is not the drug of choice,” she explained. “So it’s a select patient group that we can use GLP-1s [for].”

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In recent years, the search for effective weight loss treatments has led to the development of new medications like oral semaglutide. This groundbreaking drug has shown promising results in helping individuals lose weight and improve their overall health. If you’re interested in learning more about oral semaglutide and how it may benefit you, read on to discover what you need to know.

How does Oral Semaglutide Work?

Oral semaglutide works by mimicking the effects of a natural hormone called glucagon-like peptide-1 (GLP-1). This hormone helps regulate blood sugar levels and promotes feelings of fullness after eating. By activating the same pathways as GLP-1, oral semaglutide can help control appetite, reduce calorie intake, and promote weight loss.

When taken before meals, oral semaglutide slows down the emptying of the stomach, which can lead to a lower overall food consumption. Additionally, it can increase insulin secretion and decrease glucagon secretion, which helps lower blood sugar levels and reduce fat storage.

Overall, oral semaglutide is thought to help individuals achieve weight loss by reducing calorie intake, increasing feelings of fullness, and improving overall glucose metabolism.

Benefits of Oral Semaglutide for Weight Loss

One of the main benefits of oral semaglutide is its convenience. Unlike other GLP-1 agonists that require injections, oral semaglutide can be taken in pill form, making it more accessible and easier to use for many individuals.

Studies have shown that oral semaglutide can lead to significant weight loss in individuals who are overweight or obese. In addition to weight loss, it can also improve other metabolic markers, such as blood sugar levels, cholesterol levels, and blood pressure.

Another benefit of oral semaglutide is its potential to reduce the risk of developing obesity-related health conditions, such as type 2 diabetes, heart disease, and stroke. By promoting weight loss and improving metabolic health, oral semaglutide may help prevent these serious health issues in the long run.

Potential Side Effects of Oral Semaglutide

Like any medication, oral semaglutide can cause side effects in some individuals. Common side effects of oral semaglutide include nausea, vomiting, diarrhea, and constipation. These side effects are usually mild and tend to improve over time as the body adjusts to the medication.

In rare cases, oral semaglutide may cause more serious side effects, such as pancreatitis or thyroid tumors. It’s important to speak with your healthcare provider before starting oral semaglutide to discuss any potential risks and benefits based on your individual health profile.

If you experience any unusual or severe side effects while taking oral semaglutide, it’s important to seek medical attention immediately. Your healthcare provider can help address any concerns and determine the best course of action moving forward.

Is Oral Semaglutide Right for You?

Before starting oral semaglutide for weight loss, it’s important to consult with your healthcare provider to determine if it’s the right treatment option for you. Your healthcare provider can assess your individual health needs, preferences, and risks to help you make an informed decision about whether oral semaglutide is a suitable choice.

If you have a history of pancreatitis, thyroid problems, or other serious health conditions, oral semaglutide may not be recommended for you. Additionally, certain medications or health conditions may interact with oral semaglutide, so it’s crucial to disclose all relevant information to your healthcare provider before starting treatment.

Ultimately, the decision to use oral semaglutide for weight loss should be based on a thorough evaluation of your health status and treatment goals. Your healthcare provider can provide personalized guidance and support to help you achieve your weight loss objectives safely and effectively.

Conclusion

Overall, oral semaglutide is a promising new treatment for weight loss that offers convenience, effectiveness, and potential health benefits. By mimicking the effects of GLP-1 and promoting weight loss through appetite control and improved metabolic function, oral semaglutide may help individuals achieve their weight loss goals and improve their overall health.

Before starting oral semaglutide, it’s important to discuss the potential risks and benefits with your healthcare provider to ensure that it’s the right choice for you. With proper guidance and monitoring, oral semaglutide may be a valuable tool in your weight loss journey and help you achieve long-term success in managing your weight and health.

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