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Valerie Bertinelli, an Emmy-winning actress, celebrity chef, and author, has been an open book about her lifelong struggles with weight and body image. Over the years, her journey has evolved from chasing quick fixes to embracing a holistic, self-compassionate approach to health and wellness.

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Download "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Test and other GPAT Materials - https://play.google.com/store/apps/details?id=co.bolton.nqilv Disclaimer:- This video is for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have watched on this channel. Vildagliptin (LAF237) is an orally active antihyperglycemic agent that selectively inhibits the dipeptidyl peptidase-4 (DPP-4) enzyme. It is used to manage type II diabetes mellitus, where GLP-1 secretion and insulinotropic effects are impaired, By inhibiting DPP-4, vildagliptin prevents the degradation of glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), which are incretin hormones that promote insulin secretion and regulate blood glucose levels. Elevated levels of GLP-1 and GIP consequently results in improved glycemic control.6 In clinical trials, vildagliptin has a relatively low risk of hypoglycemia. Vildagliptin is indicated in the treatment of type II diabetes mellitus in adults. As monotherapy, vildagliptin is indicated in adults inadequately controlled by diet and exercise alone and for whom metformin is inappropriate due to contraindications or intolerance. It is also indicated as dual therapy in combination with metformin, a sulphonylurea, or a thiazolidinedione in adults patients with insufficient glycemic control despite maximal tolerated dose of monotherapy. Vildagliptin is indicated in the treatment of type II diabetes mellitus in adults. As monotherapy, vildagliptin is indicated in adults inadequately controlled by diet and exercise alone and for whom metformin is inappropriate due to contraindications or intolerance.6 It is also indicated as dual therapy in combination with metformin, a sulphonylurea, or a thiazolidinedione in adults patients with insufficient glycemic control despite maximal tolerated dose of monotherapy. Vildagliptin is also marketed in a combination product with metformin for the treatment of adults with type II diabetes mellitus who inadequately respond to either monotherapy of vildagliptin or metformin. This fixed-dose formulation can be used in combination with a sulphonylurea or insulin (i.e., triple therapy) as an adjunct to diet and exercise in adults who do not achieve adequate glycemic control with monotherapy or dual therapy. Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) are incretin hormones that regulate blood glucose levels and maintain glucose homeostasis. It is estimated that the activity of GLP-1 and GIP contribute more than 70% to the insulin response to an oral glucose challenge. They stimulate insulin secretion in a glucose-dependent manner via G-protein-coupled GIP and GLP-1 receptor signalling. In addition to their effects on insulin secretion, GLP-1 is also involved in promoting islet neogenesis and differentiation, as well as attenuating pancreatic beta-cell apoptosis. Incretin hormones also exert extra-pancreatic effects, such as lipogenesis and myocardial function Get in touch with the solution Pharmacy and Pharmacy Dictionary by just clicking the following links- Mobile App - https://play.google.com/store/apps/details?id=co.bolton.nqilv Facebook Group- https://www.facebook.com/groups/solutionpharamcy The main channel for a detailed Syllabus (Solution- Pharmacy) - https://www.youtube.com/c/SOLUTIONpushpendra E-Mail for official and other work - [email protected] #Pharmacydictionarybypushpendrapatel #Pharmacologyclass

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Struggling to stay energized and lose weight after baby #4? I got you! 💥 Here's exactly what I eat in a day to feel my best and keep the weight loss going! From a smoothie that fuels me all morning 🥬🍓 to a satisfying lunch and my favorite low-calorie chocolate mocha to power through the day ☕. Plus, my go-to electrolytes to stay hydrated and on track! 💧 It's all about finding that balance that works for YOU-let me show you how!👇 #PostpartumJourney #WeightLoss #HealthyMeals #StayEnergized #SmoothieRecipe #LunchIdeas #Electrolytes #HealthyEating #TiffanyPlate #PostpartumWeightLoss #HealthyChoices

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Let's not get sucked into the 'I have to do this' mindset. It's not about signing up for an intense Spartan Race unless that's your thing. Find what speaks to you. Do you know Jelly Roll? His journey is pure inspiration. Despite battles with weight and past struggles, he touches hearts and souls. It's a wake-up call. His health's on the line, but he's pushing for better. Starting with a 5k, it's a game-changer. And let me tell you, he's not running it like a marathon champ, but he's finishing strong. That's the spirit. We all have our journey. It's about progress, not perfection.