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(9 Jun 2017) Jurors at Bill Cosby's sexual assault trial have heard excerpts from the comedian's lurid, decade-old deposition, but explosive sections about him obtaining quaaludes and giving them to women before sex are yet to come. Prosecutors on Friday are expected to continue focusing on Cosby's testimony, giving jurors a look at his view of women, sex and the night in January 2004 that Andrea Constand says he drugged and violated her at his suburban Philadelphia home. The 79-year-old Cosby has said he will not testify, giving his deposition from Constand's civil lawsuit and a prior police interview added weight as jurors consider charges that could put him in prison for the rest of his life. A detective on Thursday read portions of the deposition covering what Cosby described as several sexual encounters with Constand, including one before the alleged assault where he said he found himself "somewhere between permission and rejection." Friday's excerpts are expected to include an exchange where Cosby, once known as America's Dad, acknowledges using quaaludes in his pursuit of women for sex. Cosby testified in 2005 and 2006 as part of a lawsuit brought against him by Constand, the former director of women's basketball operations at his alma mater, Temple University. Constand testified this week she rejected Cosby's advances and would have fought him off again had the pills not left her paralyzed and semi-conscious. He has said the sexual encounter was consensual. =========================================================== Clients are reminded: (i) to check the terms of their licence agreements for use of content outside news programming and that further advice and assistance can be obtained from the AP Archive on: Tel +44 (0) 20 7482 7482 Email: [email protected] (ii) they should check with the applicable collecting society in their Territory regarding the clearance of any sound recording or performance included within the AP Television News service (iii) they have editorial responsibility for the use of all and any content included within the AP Television News service and for libel, privacy, compliance and third party rights applicable to their Territory. Find out more about AP Archive: http://www.aparchive.com/HowWeWork Twitter: https://twitter.com/AP_Archive Facebook: https://www.facebook.com/APArchives Instagram: https://www.instagram.com/APNews/ You can license this story through AP Archive: http://www.aparchive.com/metadata/youtube/adf40a458f49a9c49e213effa378dc0f

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With the increasing prevalence of obesity worldwide, there is a growing need for effective treatments that can help individuals achieve and maintain a healthy weight. One medication that has shown promise in this regard is semaglutide tablets. Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that is already approved for the treatment of type 2 diabetes.

The Mechanism of Action of Semaglutide Tablets

Semaglutide works by mimicking the effects of GLP-1, a hormone that is released by the intestines in response to food intake. GLP-1 helps regulate blood sugar levels by stimulating the release of insulin and inhibiting the release of glucagon, a hormone that raises blood sugar levels. In addition to its effects on blood sugar, GLP-1 also plays a role in appetite regulation and satiety. By activating GLP-1 receptors, semaglutide helps promote weight loss by reducing food intake and increasing feelings of fullness.

Clinical Trials of Semaglutide for Weight Loss

Several clinical trials have been conducted to evaluate the efficacy of semaglutide tablets in promoting weight loss. One of the most well-known trials is the STEP program, which consisted of four different trials involving over 4,500 participants with obesity or overweight. The results of these trials showed that semaglutide was associated with significant weight loss compared to placebo, with some participants achieving weight loss of over 15%.

Potential Side Effects of Semaglutide Tablets

Like any medication, semaglutide tablets can cause side effects. The most common side effects reported in clinical trials include nausea, vomiting, diarrhea, and constipation. These side effects are usually mild to moderate in severity and tend to improve over time as the body adjusts to the medication. It is important to discuss any concerns about side effects with your healthcare provider before starting treatment with semaglutide.

Considerations for Long-Term Use of Semaglutide

While semaglutide tablets have been shown to be effective for promoting weight loss in the short term, it is important to consider the long-term implications of using this medication. Some studies have raised concerns about the potential for semaglutide to increase the risk of certain health conditions, such as pancreatitis and thyroid tumors. These risks need to be weighed against the benefits of weight loss when making decisions about long-term treatment with semaglutide.

Conclusion

In conclusion, semaglutide tablets have shown promise as a treatment for promoting weight loss in individuals with obesity or overweight. The medication works by mimicking the effects of GLP-1, a hormone that helps regulate blood sugar levels and appetite. Clinical trials have demonstrated the efficacy of semaglutide in achieving significant weight loss, although potential side effects and long-term risks need to be considered. Ultimately, the decision to use semaglutide for weight loss should be made in consultation with a healthcare provider, taking into account individual health needs and risk factors.

Summary

In summary, semaglutide tablets have emerged as a promising option for individuals seeking to achieve weight loss and improve their overall health. The medication’s mechanism of action involves mimicking the effects of GLP-1 to regulate blood sugar levels and appetite, leading to significant weight loss in clinical trials. While side effects such as nausea and gastrointestinal discomfort may occur, these are usually mild and transient. Long-term use of semaglutide may be associated with certain risks, which should be discussed with a healthcare provider. Overall, semaglutide represents a valuable addition to the treatment options available for individuals struggling with obesity or overweight.

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