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#podcast 1. Introduction - Definition of Erectile Dysfunction (ED) - Prevalence and Age Factors - Common Causes of ED 2. Understanding Penile Erections - Neurological and Vascular Factors - Role of Autonomic and Somatic Nerves - The Role of Nitric Oxide (NO) - Smooth Muscle Tone and Vasodilation - Penile Sinusoids and Blood Flow during Erection 3. Understanding Erectile Dysfunction and Its Associations - Factors Affecting ED - Diabetes and its Impact on Erectile Function - Neurological Disorders and ED - Chronic Renal Insufficiency and ED - Psychogenic ED - Androgen Deficiency and ED - Vascular Disease and ED - Veno-Occlusive Dysfunction and ED - Medications and Recreational Drugs and their Role in ED 4. Evaluating Erectile Dysfunction - Importance of Comprehensive Evaluation - Medical, Sexual, and Psycho-Social History - Physical Examination - Laboratory Tests and Hormone Assessment 5. Medical Treatment of Erectile Dysfunction - Androgen Therapy and its Benefits and Risks - Type 5 Phosphodiesterase Inhibitors (PDE5I) - Mechanism and Effectiveness - Cardiovascular Safety Concerns with PDE5I Use 6. Strategies for Men Who Don't Respond to PDE5 Inhibitors - Re-education on Medication Use - Dose Titration or Alternative PDE5 Inhibitor - Testosterone Level Assessment and Combination with PDE5 Inhibitors 7. PDE-5 Inhibitors and Cardiovascular Safety - Cardiovascular Safety Concerns and Studies - Cautionary Considerations for Patients with Certain Conditions - Interaction with Nitrates and Nitroglycerin 8. Conclusion - Importance of Individualized Treatment Approach - Considerations for Managing Erectile Dysfunction and Peyronie's Disease

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