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This episode I describe the science of fat loss, including how fat is mobilized and oxidized (burned) and how to increase fat burning by leveraging the nervous system. Most people don't realize it, but our neurons connect to our fat and release epinephrine/adrenaline to facilitate fat oxidation. I explain how this can be accomplished with non-exercise movements such as fidgeting to burn thousands of calories of fat a day-- a practice is rarely discussed but very well supported by the science literature. I also discuss an optimal fat loss protocol using cold to create shiver, and how specific types and timing of exercise impact fat loss. I discuss if exercising fasted indeed increases fat oxidation-- it turns out the type and duration of exercise really matters. And I discuss the use of caffeine, GLP1 from Mate or guayusa and emerging new prescription compounds for fat loss. The episode includes a lot of tools, links to cost-free resources and explanation of the science underlying each tool for fat loss. #HubermanLab #FatLoss #Science Thank you to our sponsors: InsideTracker - http://insidetracker.com/huberman ExpressVPN - http://expressvpn.com/huberman Athletic Greens - http://athleticgreens.com/huberman Cold Protocols via The Cold Plunge: https://thecoldplunge.com/pages/protocols Our Patreon page: https://www.patreon.com/andrewhuberman Supplements from Thorne: http://www.thorne.com/u/huberman Social: Instagram - https://www.instagram.com/hubermanlab Twitter - https://twitter.com/hubermanlab Facebook - https://www.facebook.com/hubermanlab/ Website - https://hubermanlab.com Timestamps: 00:00:00 Introduction 00:06:00 Fat Loss: The Key Role of Neurons 00:08:44 The First Law of Fat Loss 00:11:00 Neurons Connect To Fat! (& That Really Matters) 00:13:38 5 Pillars of Metabolism: Sleep, Essential Fatty Acids, Glutamine, Microbiome, Thyroid 00:19:20 Mindset Truly Matters: Amazing Examples of Beliefs on Fat Loss 00:23:08 Our Brain Talks To Our Fat 00:25:00 The Most Incredible & Dangerous Fat Loss Agent 00:27:28 Losing Fat Is a Two-Part Process: Mobilization and Oxidation 00:32:25 The Critical Role of Adrenaline/Epinephrine, But NOT from Adrenal Glands 00:34:45 Fidgeting & Shivering: A Powerful Science-Supported Method For Fat Loss 00:41:24 How Fidgeting Works: Promotes Epinephrine Release into Fat. “N-E-A-T” 00:44:55 Two Ways of Using Shivering To Accelerate Fat Loss 00:47:30 White, Brown & Beige Fat; & Using Cold-Induced Shiver To Burn Fat 00:50:25 How To Use Cold Properly To Stimulate Fat Loss: Succinate Release Is Key/Shiver 00:52:26 Exact Protocols: (1-5X per week); Don’t Adapt! Submerge and Exit “Sets & Reps” 00:56:15 thecoldplunge.com see “protocols” tab Cold-Shiver-Fat-Loss Tool (cost free) 00:58:03 If Fat-Loss Is Your Goal, Avoid Cold Adaptation: Remember Polar Bear Swimmers 00:58:17 Irisin: Underwhelming; Succinate Is The

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Kelly Clarkson is still showcasing her incredible slim physique, a transformation that has become the talk of the town. With her new toned figure, comes a fresh wardrobe, and what better stage to flaunt her killer outfits than her own show?

On a recent episode, she left viewers in awe as she strutted onto the stage in a curve-hugging leather dress, proving once again that she’s a style icon in her own right. The caramel-colored outfit boasted half sleeves, a high neckline, and a stylish wrap-around detail at the bodice. To complement the ensemble flawlessly, she opted for cheetah-print pointed-toe pumps, adding a touch of fierce sophistication to her look.

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If you’re eating right and exercising but still struggling to lose weight, your hormones could be the culprit. Imbalances in insulin, cortisol, estrogen, and thyroid hormones can cause your body to store fat, slow metabolism, and increase cravings—making it harder to shed unwanted weight. At Delaware Integrative Medicine, we offer comprehensive hormone testing and GLP-1 Peptide Therapy to help regulate appetite, balance metabolism, and support sustainable weight loss.

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