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Are GLP-1RAs the solution to the obesity crisis? Let's explore... Hello 👋 I'm Luke, a PhD student at the University of Oxford, with a keen interest in evidence-based decision-making, health economics, and clinical research. My goal is to help people better understand the science behind health claims so they can make informed choices. In this video, we examine claims made about GLP-1 patches, look at the research cited by companies selling them, and discuss whether they’re likely to be effective for weight loss. 🔍 Topics Covered: ✔️ What are GLP-1 patches? ✔️ What does the evidence provided say? ✔️ Are these patches misleading? ✔️ The importance of randomized controlled trials 💬 What do you think? Let me know in the comments if you've come across these patches & whether you think they actually work! ⚠️ Disclaimer This video is for educational and informational purposes only. It is based on publicly available research and my own independent analysis. It is NOT medical advice. Always consult a qualified healthcare professional before making any health decisions. 📖 References: Zheng et al (2024): https://doi.org/10.1038/s41392-024-01931-z Haase et al (2021): https://doi.org/10.1038/s41366-021-00788-4 Wilding et al (2021): https://doi.org/10.1056/nejmoa2032183 Jastreboff et al (2022): https://doi.org/10.1056/nejmoa2206038 Wilding et al (2022): https://doi.org/10.1111/dom.14725 Lincoff et al (2023): https://doi.org/10.1056/nejmoa2307563 Theis et al (2021): https://doi.org/10.1111/1468-0009.12498

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Click Here To Try My Natural Weight loss Program http://ow.ly/G1MW8 As the Days start getting colder and the days shorter and less light, our brains often start to crave comfort food and have less drive to exercise and these two things can add up to 10-20 pounds of excess weight by next summer when it’s time for body baring outfits again! To help curb the winter weight gain and help you feel fabulous all winter, inside and out, I’ve created to the Top 10 Tips for Losing Weight This Winter to make sure you can still wear your favourite shorts come springtime! Don’t Get Hungry. If you are not eating enough of the right foods and your hunger drive starts to kick in more frequently, it sends a very powerful drive from your brain to eat absolutely anything! Usually when you are hungry you are more likely to eat the high carb comfort foods that are bad for your waistline. Solution: eat smaller more frequent meals with protein at every meal, snack on a few nuts in between meals like almonds, which are full of fibre and curb hunger, and avoid heavy high carb meals like pasta, pastries, bread and pizzas. Sleep 1 extra hour each night. It has been proven in multiple large studies that getting less sleep than you need (and you need more than you think--ladies you need about 9 hours a night!) leads to gaining weight and children and adults who don’t sleep as long have higher risk for obesity and that short sleep times is an independant risk factor for obesity. This is because not getting enough sleep chronically affects the areas of the brain that control sleep cycles such as the brainstem, thalamus, and areas of the limbic system, as explained by the folks at Harvard University. Work on upping your sleep to help with weight loss effortlessly and help your mood and daytime energy levels too by gradually bringing forward your bedtime over a two week period by 5-10 minutes a day until you have reached a bedtime 1 hour earlier than when you started! Schedule in 20 minutes a day of exercise like it was the most important meeting of your day. We tend to walk less, bike less and move less in the winter months and the exercise that may be naturally built in to your day will usually decrease in the winter. The only way to battle this is to schedule 30 minutes a day to exercise, either at a gym on the treadmill while you watch your favorite tv show, at a workout class, or at home with a workout video or laying a yoga mat in your bedroom or other personal home space will you will not be disturbed in. Make it the SAME TIME each day and if you find you are really tired in the evenings and don’t have a really early work start, mornings work best to make sure your brain doesn’t come up with a million excuses to skip out after a long day! For weight loss yoga videos, and to learn how to get the healthy weight loss results you want, easily and naturally, without starving yourself or killing it at the gym, check out my Weight Management Online program here: http://askdrdani.com/natural-weightloss/ YOU CAN overcome the health issues that are holding you back from the freedom of feeling amazing every day.

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🧬 Berberin se stal hitem mezi biohackery, sportovci i lidmi hledajícími přírodní cestu ke snížení krevního cukru, cholesterolu a tělesné hmotnosti. Označuje se jako „přírodní Ozempic“ nebo „bylinný metformin“. Co o něm ale říká skutečná věda? V tomto videu rozebírám: ✅ Jak funguje berberin (aktivace AMPK, ovlivnění GLP-1, vliv na LDL receptory) ✅ Jeho účinky na glykémii a HbA1c ✅ Možný vliv na hubnutí ✅ Efekty na cholesterol, triglyceridy a aterosklerózu ⚠️ Rizika, lékové interakce a pro koho berberin není vhodný Vše podloženo nejnovějšími vědeckými studiemi. Na konci videa se dozvíte, jestli má berberin v praxi smysl – a pro koho ano, a pro koho ne. 📌 Sledujte mě pro další videa o dlouhověkosti, zdraví a efektivním tréninku. 📚 Odkazy na studie a další informace najdete v popisu níže. #dlouhovekost #zdravi #pohyb #hubnuti #ozempic #mounjaro #berberin #suplementy #biohacking #zdravyzivot #kratkecviceni 🚀BONUSOVÝ OBSAH, TEA TIME PODCAST, E-BOOKY, TIPY, AUDIO NOVÝCH EPIZOD A MNOHO DALŠÍHO NAJDEŠ NA: https://www.forendors.cz/miloslav.sindelar Moc díky za podporu! Kontakt: [email protected] https://www.linkedin.com/in/miloslav-šindelář-68a714230/ 👉Komplexní webinář o dlouhověkosti (NOVÝ TERMÍN): https://www.konec-prokrastinace.cz/prednaska/registrace/2025-06-30-webinar-dlouhovekost/ __________________________________________ Longevity CZ/SK soukromá skupina: https://www.facebook.com/groups/984517159922769 Edukační příspěvky: https://x.com/Milosval1 https://www.instagram.com/milosval/ __________________________________________ Zdroje a studie: https://pmc.ncbi.nlm.nih.gov/articles/PMC9650693/ https://pubmed.ncbi.nlm.nih.gov/19945441/ https://pmc.ncbi.nlm.nih.gov/articles/PMC8874997/ https://pmc.ncbi.nlm.nih.gov/articles/PMC2410097/ https://www.mdpi.com/2072-6643/14/17/3459 https://link.springer.com/article/10.1186/s12902-023-01442-y https://pmc.ncbi.nlm.nih.gov/articles/PMC4529214/ https://www.sciencedirect.com/science/article/pii/S1744388119303871 https://link.springer.com/chapter/10.1007/112_2020_42 __________________________________________ Kapitoly ve videu: 0:00 Úvod 00:50 Mechanismy účinku 4:17 Benefity berberinu 9:03 Rizika a interakce 14:16 Doporučení a shrnutí