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The 2024 Lasker–DeBakey Clinical Medical Research Award has been presented for the discovery of GLP-1 and its application to the treatment of obesity. Lasker winner Svetlana Mojsov, PhD, discusses her role in this innovative discovery and more with JAMA Senior Editor Anne Rentoumis Cappola, MD, ScM. Related Content: Chemistry Matters—From a Putative Peptide to Effective Treatments for Diabetes and Obesity https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.17571?utm_campaign=podcasts&utm_medium=social&utm_source=youtube&utm_content=public Discovery of cGAS as a DNA-Sensing Enzyme That Triggers Inflammation https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.17873?utm_campaign=podcasts&utm_medium=social&utm_source=youtube&utm_content=public GLP-1 for Treating Obesity—Origin, History, and Evolution https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.18000?utm_campaign=podcasts&utm_medium=social&utm_source=youtube&utm_content=public AIDS in Africa—Impact of Research https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.18271?utm_campaign=podcasts&utm_medium=social&utm_source=youtube&utm_content=public Podcast was originally published on September 19, 2024. https://edhub.ama-assn.org/jn-learning/audio-player/10.1001/jama.2024.18624?utm_campaign=podcasts&utm_medium=social&utm_source=youtube&utm_content=public --------------------------------------------------------------------------------- Follow JAMA Author Interviews on: Youtube: https://www.youtube.com/playlist?list=PL4VOPuLXRs1dWJCIIu2iOIOWRGUc0nTOU Apple Podcasts: https://podcasts.apple.com/us/podcast/jama-author-interviews-covering/id410339697 Spotify: https://open.spotify.com/show/61HE3v2dmxyg3nsIRAK25C?si=bcbb384405d44b71 Pocket Casts: https://pca.st/DAh2 Your podcast app of choice: https://pod.link/410339697 Website: https://jamanetwork.com/journals/jama/pages/jama-author-interviews --------------------------------------------------------------------------------- For more from JAMA • https://www.jama.com • https://www.facebook.com/JAMAJournal • https://www.twitter.com/JAMA_Current • https://www.linkedin.com/company/jamanetwork Follow the JAMA Network • https://www.jamanetwork.com • http://www.jamanetworkaudio.com • https://www.facebook.com/JAMANetwork • https://www.twitter.com/JAMANetwork • https://www.instagram.com/JAMANetwork • https://www.pinterest.com/JAMANetwork

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Today Dayna Summers joins me to talk about the pros and cons of her experience with 3 different GLP-1 agonists (Semaglutide, Ozempic, and Mounjaro) and what led to her choice to begin taking them. After a complicated upbringing, Dayna went on to become a marathon runner, triathlete, and bodybuilder. She built her Real Estate brokerage from the ground up & is now among the top 1% of realtors, nationwide. While at the top of her game in 2017, complications in her personal life lead to an onslaught of stress, weight gain, and a devastating diagnosis of type 2 diabetes. A lot of us have heard the buzz surrounding these weight loss prescriptions, and most of us know at least one person who is taking them. Ozempic, Mounjaro, Wegovy, and Semaglutide are names that, by now, many of us are familiar with. The reaction from the public regarding these medications is pretty split, depending on who you ask. Some will suggest that those who decide to go the route of weight loss prescriptions are taking the easy way out. They are accused of being lazy, lacking discipline & will power. As with most polarizing topics, there are two sides to consider before rushing to judgment and I think Dayna’s story will help us understand things a bit differently. Subscribe to Humanity Unlocked on Apple Podcasts! https://podcasts.apple.com/us/podcast/humanity-unlocked/id1687164732 Follow us on Instagram! https://www.instagram.com/humanityunlockedpodcast/ Find us on TikTok! https://www.tiktok.com/@humanityunlockedpodcast?is_from_webapp=1&sender_device=pc #GLP1 #GLP1agonists #weightloss #type2diabetes #health #fitness #wellness #motivation #inspiration #podcast #ozempicweightloss #wegovyweightloss #mounjaroweightloss #semaglutideweightloss #weightlossmedication

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