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As the popularity of GLP-1 (Glucagon-Like Peptide-1) agonists including semaglutide - branded as Wegovy or Ozempic, and tirzepatide (dual GIP/GLP-1 receptor agonist) - branded as Zepbound or Mounjaro, for the management of obesity, type 2 diabetes, and other metabolic conditions increases, so too does the need to assess the advantages and potential downsides of long-term use. While these medications can be very effective for weight control and diabetes support, questions around the optimal dietary approach in users remain. Join Dr. Bojana Jankovic Weatherly and Melissa Reade (MS, CDN, CNS) for an informative discussion addressing everything you need to know about GLP-1 agonists. We hope this conversation provides you with insights that you can bring to your physician if you are interested in taking these medications, or are already on them. BOJANA MD Website: https://drbojana.com Follow Dr. Bojana on Instagram: https://www.instagram.com/dr_bojana/?hl=en Assessing the Benefits, Risks, and Long-Term Metabolic Effects of GLP-1 Agonists: https://drbojana.com/assessing-the-benefits-risks-and-long-term-metabolic-effects-of-glp-1-agonists/ DISCLAIMER: All information in this video, including, but not limited to, the video itself, text, graphics, images and other material contained in this video, is strictly for informational purposes only. The content is NOT intended to serve as or be a substitute for professional medical, pediatric or psychiatric advice, nor is it designed to suggest any specific diagnosis or treatment. Please always seek medical advice from your physician or a qualified health care provider regarding any medical questions, condition or treatment, particularly before making any changes to your health care regimen, medications or lifestyle habits. Never disregard professional medical advice or delay seeking help from a health care provider due to something you have heard, seen or read in this video. Reliance on any information in this video, specifically applied to your own case, is solely at your own risk.
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Medications can be a powerful tool on your weight loss journey, but they’re just one part of the puzzle! When it comes to treating obesity, it's not just about cosmetic care; it’s about medical care. That’s why working with a healthcare provider makes all the difference. 👩⚕️✨ While many patients see success without medications, options like GLP-1s can now help people lose up to 15–20% of their weight, compared to the usual 5–10% with other meds. Impressive, right? #MedicalWeightLoss #ObesityCare #GLP1 #WeightLossSupport #HealthyJourney #ScienceBackedResults Dr. A has been helping patients lose weight since 2009, guiding them toward better health with sustainable solutions. Plus, she is accepting new patients! If you’re ready to start your weight loss journey, call or text us today at (614)442-2600 or visit https://prohealthservices.org/. Follow us on Facebook: https://www.FaceBook.com/ProHealthDrA Follow us on Instagram: https://www.Instagram.com/ProHealthDrA Follow us on YouTube: https://www.YouTube.com/@prohealthDrA Follow us on TikTok: https://www.TikTok.com/@ProHealthDrA
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This is an excerpt of the keynote 'Current Status and Potential Future of Obesity Therapies' by Associate Vice President James Trevaskis (Eli Lilly) at the conference Metabolism Day 2025. He provides an insightful overview of the current obesity therapeutics landscape and future innovations beyond GLP-1 receptor agonists, discusses the evolution of obesity treatments, highlights the success of GLP-1s like semaglutide and tirzepatide, while exploring emerging therapies including: Retatrutide - Eli Lilly's tri-agonist (GIP/GLP-1/glucagon) showing up to 24% weight loss Small molecule GLP-1 agonists - Oral alternatives like orforglipron Amylin-based therapies - The next major non-incretin class for obesity treatment Combination approaches - Including activin receptor inhibitors to preserve lean muscle mass during weight loss Trevaskis addresses key challenges in obesity drug development, including patient response variability, body composition changes, and the need for novel biological targets. He also shares Eli Lilly's innovative CRISPR-based approach for rapid target validation in obesity research. This talk offers valuable insights into the future of obesity medicine, discussing both the promise and challenges of developing more effective, personalized treatments for metabolic disease.
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An Overview of Lauren Manzo’s Remarkable Transformation
Lauren Manzo, known for her appearance on the reality television series “The Real Housewives of New Jersey,” has made headlines not just for her family drama but for her incredible journey of personal transformation. In recent years, she has achieved an impressive 80-pound weight loss that has left fans and followers both inspired and curious about her approach to diet and fitness. This article delves into the game-changing diet hacks that contributed significantly to her success. Her journey is not simply about shedding pounds; it represents a profound shift in her lifestyle, emotional health, and overall well-being.

Weight loss journeys can often feel overwhelming, with countless diets and fitness regimens available promising quick results. However, Lauren’s approach stands out due to its focus on sustainability and enjoyment rather than deprivation and strict rules. She emphasizes that effective weight loss should not feel like punishment; instead, it should be a celebration of the self and a path toward greater health. By changing her relationship with food and adopting mindful eating habits, Lauren has managed to achieve her weight loss goals while still enjoying the foods she loves.
In this article, we will explore the pivotal diet hacks that facilitated Lauren’s transformation. These strategies are approachable and practical, making them applicable to anyone looking to make a change in their life. From understanding portion control to utilizing the benefits of nutrient-rich foods, Lauren’s approach offers key insights into how lifestyle changes can lead to sustainable health benefits. Join us as we unravel the techniques that helped Lauren Manzo redefine her life and achieve her body goals, providing inspiration for others who wish to embark on a similar journey.
Understanding Portion Control: A Key to Success
One of the cornerstones of Lauren Manzo’s diet transformation has been her focus on portion control, a concept often overlooked in today’s fast-paced eating culture. People frequently consume more than they realize, especially when dining out or snacking mindlessly. Lauren’s journey began by shifting her awareness towards the amount of food she was consuming. By learning to gauge appropriate serving sizes, she not only reduced her caloric intake but also embraced a more mindful way of enjoying her meals.
Learning how to measure portions does not require the use of complicated tools or scales. Instead, simple visual cues can assist individuals in identifying appropriate portions. For instance, Lauren discovered that a fist-sized portion of carbohydrates, a palm-sized piece of protein, and a plate full of vegetables was a balanced approach to constructing her meals. This visual representation made it easier for her to stay on track without feeling restricted or deprived. Over time, as Lauren incorporated these practices, she began to understand her body’s hunger signals better, allowing her to eat when truly hungry and stop when satisfied.
Moreover, practicing portion control has significant psychological benefits. By allowing herself to enjoy a wide variety of foods while keeping portions in check, Lauren formed a healthier relationship with food. This control alleviated the feelings of guilt and shame often associated with eating certain foods, empowering her to indulge in moderation. With less deprivation, she found it easier to stick with her eating habits over the long term, ultimately leading to her remarkable 80-pound weight loss.
The Power of Nutrient-Dense Foods
Another impactful hack from Lauren Manzo’s diet journey is her commitment to incorporating nutrient-dense foods into her meals. Instead of focusing solely on calorie restriction, Lauren shifted her attention to the quality of the foods she was consuming. Nutrient-dense foods, which are rich in vitamins, minerals, and other essential nutrients, not only support overall health but also promote feelings of fullness and satisfaction. Filling her plate with vegetables, lean proteins, healthy fats, and whole grains was a game changer for her weight loss journey.
Lauren’s commitment to meal prepping played a vital role in achieving this. By preparing meals in advance, she ensured that she always had healthy options available on busy days when temptation might lead her astray. This practice empowered her to make better food choices. For instance, she began each week by preparing a variety of salads packed with greens, colorful vegetables, and lean proteins. These nutrient-rich meals became staples in her diet, demonstrating that healthy eating doesn’t have to be boring or monotonous.
The incorporation of nutrient-dense foods also allowed Lauren to explore new ingredients and recipes. She became adventurous, stepping outside her comfort zone by trying different grains, legumes, and vegetables that she had previously overlooked. This not only introduced her to a broader array of flavors and textures but also kept her meals exciting. By integrating diverse nutrients into her diet, Lauren nurtured her body while simultaneously engaging in the joy of cooking and eating.
Mindful Eating: Cultivating a Positive Relationship with Food
A significant aspect of Lauren Manzo’s transformation can be attributed to her practice of mindful eating. In an era where many individuals are distracted by screens, busy schedules, and fast-paced lifestyles, it can be easy to lose touch with one’s body and its dietary needs. Lauren recognized the importance of reconnecting with the act of eating. By intentionally slowing down and paying attention to her meals without distraction, she learned to savor each bite and appreciate her food fully.
Mindful eating involves engaging all the senses while eating. Lauren found joy in the colors, textures, and flavors of her meals. She took the time to notice how certain foods made her feel both physically and emotionally. This awareness helped her discern what nourished her body and what did not. By practicing gratitude for her meals, Lauren cultivated a deeper appreciation of food, elevating her experience and reinforcing her commitment to healthy eating habits.
Furthermore, mindful eating has numerous benefits, like reducing emotional eating and improving digestion. Lauren noticed that when she was fully present during meals, she was less likely to eat out of boredom or stress. By focusing on the experience rather than mindlessly consuming food, she could listen to her body’s signals of hunger and fullness more accurately. This profound connection not only enhanced her relationship with food but also contributed to her sustainable weight loss success.
Staying Active: The Role of Fitness in Weight Loss
While Lauren Manzo’s weight loss is primarily rooted in her dietary changes, staying active plays an integral role in her transformation. Engaging in physical activity not only enhances the effectiveness of healthy eating but also promotes numerous overall wellness benefits. After deciding to prioritize her health, Lauren explored different types of exercises to find what felt most enjoyable and sustainable for her lifestyle. This exploration was crucial for her motivation, and it helped her integrate fitness into her daily routine seamlessly.
Lauren embraced a combination of strength training, cardio, and flexibility exercises. She realized that varying her workouts kept things fresh and exciting, preventing feelings of monotony. Strength training helped her build muscle, which is essential for increasing metabolism, while cardio workouts provided an effective means of burning calories. By incorporating activities she enjoyed, such as dancing or hiking, Lauren was able to cultivate a positive relationship with exercise, making it something she looked forward to rather than a chore.
Additionally, Lauren benefited from the sense of community and support that came with engaging in group workouts or fitness classes. Surrounding herself with like-minded individuals kept her motivated to stay accountable to her goals. She discovered that fitness was not just about weight loss but also about cultivating friendships, sharing experiences, and celebrating achievements. The combination of enjoyment, social interaction, and physical activity contributed to Lauren’s emotional well-being, proving that the journey to a healthier self can indeed be fun.
Final Thoughts on Lauren Manzo’s Weight Loss Journey
Lauren Manzo’s transformational journey is a testament to the power of dedication, mindful practices, and the right lifestyle changes. Her emphasis on portion control, nutrient-dense food choices, mindful eating, and incorporating enjoyable physical activity has led to her impressive 80-pound weight loss and a healthier overall lifestyle. Each of these strategies reflects her commitment to not only losing weight but also enhancing her quality of life. This journey shows that achieving one’s health goals is possible, and each small change can lead to significant, lasting results.
People often wonder how sustainable weight loss can be achieved. The answer lies in finding a balance that fits one’s lifestyle. Lauren’s story serves as an excellent reminder that it’s essential to listen to one’s body, prioritize what makes you feel good, and enjoy the process. It’s not merely about the numbers on a scale but rather about creating a fulfilling life that embraces health, passion, and happiness.
As Lauren continues to inspire her followers with her journey, she reinforces the notion that anyone can take charge of their health. Her tips can serve as valuable tools for anyone looking to embark on a weight loss journey or simply wishing to live a healthier life. The key is to start small, remain consistent, and remember that it is the cumulative effect of these small changes that leads to monumental transformations.
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