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👇 Visit The Proof website for the full show notes and supporting studies. 👇 https://theproof.com/podcast/ You’ve probably heard the claim: "If you’re lean and metabolically healthy, high LDL doesn’t matter." In low-carb circles, it’s more than a claim, it’s a permission slip to eat as much butter and bacon as you like. But is that confidence backed by science? In this solo episode, I break down the much-discussed KETO-CTA study that aimed to assess cardiovascular risk in lean individuals following a long-term ketogenic diet. With commentary from Dr. Alan Flanagan, who co-authored a formal critique of the study, we examine the actual data and how it was presented. Whether you follow keto, are concerned about your LDL, or just want clarity on cardiovascular risk, this episode cuts through the noise. What we cover: - Who are Lean Mass Hyper-Responders (LMHRs) and why they were studied - What the KETO-CTA study actually measured and why calling it a "trial" is misleading - The significance of Non-Calcified Plaque Volume (NCPV) and Percent Atheroma Volume (PAV) - Why the primary outcome data was omitted from the published paper and why that matters - ApoB levels and plaque progression: what the study showed and what it didn't - The role of exploratory vs. pre-registered outcomes in research - Problems with media coverage and misleading headlines - How this study compares to others using similar imaging methods - Why the average subject showed plaque growth 4x faster than expected - What this means for people on a ketogenic diet with elevated ApoB - The importance of responsible science communication Subscribe and stay connected: Found this episode valuable? Subscribe to The Proof on YouTube and hit the notification bell to stay updated. Listening on Spotify or Apple Podcasts? Follow the show to ensure you never miss an episode. Support the show: The best way to support the show is to use the products and services offered by our sponsors. Visit http://theproof.com/friends for exclusive discounts. If you have any additional questions you would like answered in the future, let me know in the comments. Enjoy, friends. Simon This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Head to https://38tera.com/?ref=SIMON and use code PROOF for 25% off at checkout. Bragg Bragg Organic Apple Cider Vinegar is raw, unfiltered, and naturally fermented with 100% organic apples, always with the live “Mother” in every bottle. Get 20% off your first order at https://www.bragg.com with promo code SIMON. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on http://im8health.com/ Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at http://eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. LMNT Stay hydrated with LMNT. Get a free Sample Pack of LMNT’s most popular drink mix flavors with any purchase at http://drinklmnt.com/simon Find your favorite LMNT flavor, or share with a friend. And if you don’t like it? Full refund, no questions asked. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on http://join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) - Creator of http://theproof.com/ - Host of https://theproof.com/podcast/ - Author of https://theproof.com/book/ Subscribe & Connect: - YouTube: https://www.youtube.com/c/TheProofWithSimonHill?sub_confirmation=1 - Apple Podcasts: https://podcasts.apple.com/au/podcast/the-proof-with-simon-hill/id1367773989 - Spotify: https://open.spotify.com/show/7bAIJCVgnquxXZuQCdZyTi?si=84831dc34dc9408b - Instagram: https://www.instagram.com/theproof/ - X: https://x.com/theproof - Facebook: https://facebook.com/theproofwithsimonhill - Nourish your gut with my https://theproof.com/ferments/ and download my https://theproof.com/mealplan.

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Semaglutide is a medication commonly used to treat type 2 diabetes by helping the body regulate blood sugar levels. However, recent studies have shown that it can also be effective in promoting weight loss. When injected, semaglutide can help reduce appetite, control cravings, and increase feelings of fullness, making it easier to adhere to a healthy diet and lose weight in the process.

Proper Technique for Injecting Semaglutide

Before injecting semaglutide, it is essential to wash your hands thoroughly with soap and water. Select a clean, dry injection site on your abdomen or thigh and wipe the area with an alcohol swab. Remove the cap from the needle, being careful not to touch the needle itself. Hold the syringe like a pencil and insert the needle at a 90-degree angle into the skin. Slowly push the plunger down to inject the medication and then remove the needle. Apply gentle pressure to the injection site with a clean cotton ball to stop any bleeding.

It is recommended to rotate injection sites to prevent skin irritation or the formation of lumps under the skin. Keep track of the injection sites to ensure you are not injecting semaglutide into the same spot repeatedly. If you are unsure about the proper technique for injecting semaglutide, consult with your healthcare provider or a trained medical professional for guidance.

After injecting semaglutide, dispose of the used needle and syringe in a puncture-proof container. Do not recap the needle or dispose of it in regular household trash. Properly dispose of the container following local regulations or guidelines to prevent needle-stick injuries and protect the environment.





Tips for Injecting Semaglutide

It is essential to follow the prescribed dosage and injection schedule provided by your healthcare provider. Skipping doses or injecting more than recommended can affect the effectiveness of semaglutide and may lead to adverse effects. If you miss a dose, take it as soon as you remember unless it is almost time for your next scheduled dose.

Monitor your blood sugar levels regularly while taking semaglutide, especially if you have diabetes. Semaglutide can affect your body’s insulin response and may require adjustments to your diabetes medication or insulin dosage. Keep a log of your blood sugar readings and report any significant changes to your healthcare provider.

Stay hydrated and maintain a balanced diet while using semaglutide for weight loss. Drinking plenty of water and eating a variety of nutritious foods can support your weight loss goals and enhance the effects of the medication. Avoid high-calorie, processed foods and prioritize fresh fruits, vegetables, lean proteins, and whole grains.

Possible Side Effects of Semaglutide Injection

Like any medication, semaglutide can cause side effects in some individuals. Common side effects of semaglutide injection may include nausea, diarrhea, vomiting, abdominal pain, and constipation. These side effects are usually mild and temporary, but if they persist or worsen, contact your healthcare provider for further evaluation.

In rare cases, semaglutide may cause more severe side effects such as pancreatitis, hypoglycemia, kidney problems, thyroid tumors, or allergic reactions. Seek immediate medical attention if you experience symptoms like severe abdominal pain, low blood sugar levels, difficulty breathing, or swelling of the face, lips, or throat. Your healthcare provider will monitor your progress and adjust your treatment plan as needed to minimize the risk of adverse effects.

If you have any concerns about the safety or effectiveness of semaglutide for weight loss, discuss them with your healthcare provider before starting treatment. Your provider can offer personalized advice based on your medical history, current medications, and weight loss goals to help you make an informed decision about incorporating semaglutide into your weight loss plan.

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SuperCut Keto is a great food supplement which is developed to help people fight fat and unhealthy body. This solution is available in capsule form and it’s every bottle contains 60 easy-to-swallow capsules. The formula is a proprietary blend of potent and effective ingredients which helps you to achieve your weight loss goals. It aids digestion, increases energy levels and fights free radicals.

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Semaglutide is a medication that has been gaining attention for its potential use in weight loss. Originally approved for the treatment of type 2 diabetes, semaglutide has been shown to also aid in weight loss when used at higher doses. But how much semaglutide should be used for weight loss, and what are the dosing recommendations?

What is Semaglutide?

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that works by mimicking the effects of incretin hormones in the body. Incretins help to regulate blood sugar levels by stimulating the release of insulin and decreasing the production of glucagon. In addition to its effects on blood sugar, semaglutide has also been shown to decrease appetite and promote weight loss.

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When used for weight loss, semaglutide is typically prescribed at higher doses than when used for diabetes management. The higher doses of semaglutide have been shown to lead to greater weight loss results, making it an attractive option for individuals looking to lose weight.

Dosing Recommendations

The dosing recommendations for semaglutide for weight loss can vary depending on the specific formulation of the medication being used. Currently, the most common formulation used for weight loss is semaglutide 2.4 mg once weekly. This dosage has been shown to be effective in aiding weight loss when combined with diet and exercise.

Prior to starting treatment with semaglutide for weight loss, it is important for individuals to consult with their healthcare provider. The healthcare provider will be able to determine the appropriate dosage based on the individual’s medical history, current medications, and weight loss goals.

Potential Side Effects

While semaglutide has been shown to be effective for weight loss, it is important to be aware of potential side effects associated with the medication. Common side effects of semaglutide may include nausea, vomiting, diarrhea, and constipation. These side effects typically subside over time as the body adjusts to the medication.

In rare cases, more serious side effects such as pancreatitis or gallbladder problems may occur. Individuals should contact their healthcare provider immediately if they experience severe abdominal pain, persistent nausea or vomiting, or jaundice while taking semaglutide.

Monitoring and Follow-Up

Individuals who are prescribed semaglutide for weight loss should be closely monitored by their healthcare provider. Regular follow-up appointments will allow the healthcare provider to track progress, adjust dosages if needed, and address any concerns or side effects that may arise during treatment.

In addition to regular check-ins with the healthcare provider, individuals should also continue to follow a healthy diet and exercise regimen while taking semaglutide for weight loss. These lifestyle modifications will help to maximize the effectiveness of the medication and support long-term weight loss goals.

Conclusion

Semaglutide can be a valuable tool for individuals looking to achieve weight loss goals. By following dosing recommendations, being aware of potential side effects, and maintaining regular monitoring and follow-up with healthcare providers, individuals can successfully incorporate semaglutide into their weight loss journey.

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Queen Latifah is a renowned actress, singer, and producer in the entertainment industry. Over the years, she has been known for her talent, charisma, and confidence. However, like many people, Queen Latifah struggled with her weight and overall health. In recent years, she has made significant changes to her lifestyle, resulting in a noticeable weight loss and improved health. Her journey is not only inspiring but also serves as a motivation for others who are looking to make positive changes in their own lives.

Queen Latifah’s Motivations

Queen Latifah’s motivations for losing weight and improving her health are multi-faceted. One of the main reasons behind her decision to focus on her health was her own well-being. She realized that being overweight was affecting her energy levels, overall health, and quality of life. Additionally, as a public figure, Queen Latifah wanted to set a positive example for her fans and followers. She understood the impact her actions could have on others, especially those struggling with similar challenges.

Another important motivation for Queen Latifah was her desire to have longevity in her career. As an actress and performer, maintaining good health is essential for her to continue working and pursuing her passion. By taking control of her health and weight, Queen Latifah was not only investing in herself but also in her future career opportunities.

Furthermore, Queen Latifah’s personal growth and self-improvement journey played a significant role in her decision to focus on her health. She viewed the process of losing weight and becoming healthier as a way to challenge herself, push her limits, and grow as an individual. This mindset shift helped her stay motivated and committed to her goals, even when faced with obstacles and setbacks.

Queen Latifah’s Methods

Queen Latifah’s weight loss journey involved a combination of healthy eating, regular exercise, and lifestyle changes. One of the key aspects of her approach was adopting a balanced and nutritious diet. She focused on incorporating more whole foods, fruits, vegetables, lean proteins, and healthy fats into her meals. Queen Latifah also made an effort to reduce her intake of processed foods, sugar, and unhealthy snacks, which helped her manage her calorie intake and improve her overall nutrition.

In addition to making changes to her diet, Queen Latifah committed to a consistent exercise routine. She engaged in a variety of physical activities, including cardio, strength training, yoga, and dancing. By staying active and incorporating different types of workouts into her routine, Queen Latifah was able to burn calories, build muscle, and improve her overall fitness levels. Regular exercise also helped her stay motivated, boost her mood, and maintain her weight loss progress.

Alongside diet and exercise, Queen Latifah prioritized self-care, stress management, and mental well-being as part of her health improvement journey. She focused on getting enough rest, practicing mindfulness, and seeking support from friends, family, and health professionals. By taking a holistic approach to her health, Queen Latifah was able to address not only the physical aspects of weight loss but also the emotional and psychological factors that play a role in overall well-being.

Queen Latifah’s Impact

Queen Latifah’s weight loss and health improvement journey have had a positive impact on her life, career, and relationships. By prioritizing her health and well-being, she has experienced increased energy, stamina, and confidence, which have benefited her both personally and professionally. Queen Latifah’s transformation has inspired others to make positive changes in their own lives, showing that with dedication, perseverance, and support, anyone can achieve their health and fitness goals.

Moreover, Queen Latifah’s willingness to share her journey and be transparent about her challenges has resonated with many people who struggle with weight and health issues. Her authenticity and vulnerability have created a sense of connection and relatability, making her a role model for those seeking guidance, motivation, and encouragement on their own paths to wellness. Queen Latifah’s impact extends beyond her personal achievements, as she continues to inspire others to prioritize their health, embrace self-love, and strive for a better quality of life.

Overall, Queen Latifah’s weight loss journey is a testament to the power of determination, resilience, and self-care. Her story serves as a reminder that it is never too late to make positive changes, and that with the right mindset and support system, anything is possible. Queen Latifah’s motivations and methods for health improvement are not only inspiring but also serve as a source of empowerment for those who are on their own paths to transformation. As she continues to evolve and grow, Queen Latifah’s journey remains a beacon of hope and inspiration for anyone looking to make a difference in their health and well-being.

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