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Essential Nutrition Priorities for GLP-1 Users: A Comprehensive Guide In this insightful video, Christopher and Laraine Durham, known as 'The Downsized,' dive into the critical nutritional guidance necessary for individuals using GLP-1 medications such as Zepbound, Wegovy, Ozempic, Mounjaro, Semaglutide, and Tirzepatide to treat obesity. With a combined weight loss of more than 150 pounds, Christopher and Laraine share their personal experiences and the lessons they've learned along the way. This content, representing the second video in their series on GLP-1s and nutrition, discusses eight crucial nutrition priorities outlined by the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and the Obesity Society. The guidance titled 'Nutritional Priorities to Support GLP-1 Therapy for Obesity,' published across four peer-reviewed journals in 2025, emphasizes a personalized treatment plan, baseline nutrition assessment, managing gastrointestinal side effects, emphasizing nutrient-dense foods, preventing micronutrient deficiencies, prioritizing protein to preserve lean mass, maximizing weight loss through nutrition, and addressing lifestyle factors beyond food. The information is broken down for ease of understanding and practical application, making it accessible for patients aiming to enhance their treatment experience and overall health. The video encourages maintaining a balanced diet, regular physical activity, proper sleep, stress management, and the importance of community support while on GLP-1 therapy. The episode ends with a call to action for viewers to like, subscribe, and engage with further content from The Downsized to continue their health journey. https://www.sciencedirect.com/science/article/pii/S0002916525002400 DOWNSIZED GLP-1 COMPANION PRODUCT STORE: https://thedownsized.org/downsized-store Join CLUB DOWNSIZED: https://www.youtube.com/@thedownsized/join DOWNSIZED WEBSITE: https://thedownsized.org/ FOR SPONSORSHIPS, BRAND DEALS & COLLABS: https://thedownsized.org/contact/ 00:00 Introduction to GLP-1 and Obesity Treatment 00:29 Meet the Hosts: Christopher and Laraine Durham 01:00 Overview of GLP-1 Nutrition Guidance 02:09 Priority 1: Personalized Treatment Plans 04:16 Priority 2: Assess Nutrition at Baseline 05:27 Priority 3: Managing Gastrointestinal Side Effects 07:16 Priority 4: Emphasize Nutrient-Dense Foods 09:11 Priority 5: Prevent Micronutrient Deficiencies 11:10 Priority 6: Prioritize Protein and Preserve Lean Mass 12:52 Priority 7: Maximize Weight Loss and Metabolic Health 14:52 Priority 8: Address Lifestyle Beyond Food 18:40 Conclusion and Final Thoughts

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The ketogenic diet, often referred to as the keto diet, has become increasingly popular for its effectiveness in promoting weight loss and improving overall health. By consuming low-carb, high-fat foods, the body enters a state of ketosis, where it burns fat for energy instead of carbohydrates. While the keto diet can provide numerous benefits, some people may find it challenging to maintain due to its strict restrictions on carb intake. However, by incorporating apple cider vinegar (ACV) into your keto journey, you can enhance the effectiveness of the diet and potentially accelerate your weight loss goals.

Benefits of Combining Keto and ACV

Apple cider vinegar has long been touted for its numerous health benefits, including aiding in weight loss, improving digestion, and reducing blood sugar levels. When combined with the keto diet, ACV can provide several additional advantages that can help you achieve your health and wellness goals more efficiently.

One of the main benefits of incorporating ACV into a keto diet is its potential to increase feelings of fullness and reduce appetite. The acetic acid found in ACV has been shown to promote feelings of satiety, which can help prevent overeating and reduce calorie intake, leading to weight loss.

Additionally, ACV can help regulate blood sugar levels, which is especially important for individuals following a keto diet. By stabilizing blood sugar levels, ACV can prevent spikes and crashes in energy levels, helping you maintain a steady supply of energy throughout the day.

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How to Incorporate ACV into Your Keto Diet

There are several ways to incorporate apple cider vinegar into your keto diet to maximize its benefits. One of the simplest methods is to mix a tablespoon of ACV with a glass of water and drink it before meals. This can help promote digestion, reduce cravings, and enhance the fat-burning effects of the keto diet.

You can also use ACV as a salad dressing by mixing it with olive oil, herbs, and spices. This not only adds flavor to your meals but also provides the benefits of ACV in a delicious and easy-to-consume form. Additionally, you can incorporate ACV into your cooking by using it as a marinade or sauce for meats and vegetables.

Potential Side Effects and Precautions

While ACV can offer numerous benefits when combined with a keto diet, it is essential to be aware of potential side effects and precautions. Consuming large amounts of ACV can lead to digestive issues, tooth enamel erosion, and interactions with certain medications. It is recommended to start with small doses of ACV and gradually increase consumption to avoid any adverse effects.

Additionally, ACV is highly acidic and can cause irritation or damage to the esophagus if consumed in its undiluted form. It is essential to dilute ACV with water or mix it with other ingredients to minimize the risk of irritation. If you have any underlying health conditions or concerns, it is advisable to consult with a healthcare professional before incorporating ACV into your keto diet.

Conclusion

In conclusion, combining apple cider vinegar with a ketogenic diet can amplify the benefits of both practices and enhance your weight loss journey. By incorporating ACV into your daily routine, you can experience increased feelings of fullness, improved digestion, and stabilized blood sugar levels. However, it is essential to consume ACV in moderation and be mindful of any side effects or precautions. With the right approach, ACV can be a valuable addition to your keto journey and help you achieve your health and wellness goals more effectively.

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Exploring Personalized Weight Loss with Weight Trekker: An Interview with Al Maloney In this episode of The Downsized, host Laraine Durham discusses the use of GLP-1 medications for weight loss, sharing her personal success story of losing over 50 pounds with compounded Tirzepatide. Laraine is joined by Al Maloney, a statistician and clinical pharmacologist, who introduces his new app, Weight Trekker. Designed to help users personalize their dosing of GLP-1 medications, the app offers functionalities to track weight, side effects, and overall treatment satisfaction. Al explains the importance of personalized dosing and how the app can predict weight loss trajectories and help users make informed decisions about their treatment. The episode provides insights into the potential benefits of integrating apps with drug therapies to improve patient outcomes. https://www.alanmaloney.com/ The APP ON APPLE STORE: https://apps.apple.com/no/app/weight-trekker/id6651851838 We use Mochi Health: https://joinmochi.com/. Use Laraine’s code for $40 off: QIYGO8. DOWNSIZED WEBSITE: https://thedownsized.org/ JOIN CLUB DOWNSIZED: https://www.youtube.com/@thedownsized/join DOWNSIZED GLP-1 COMPANION PRODUCT STORE: https://thedownsized.org/downsized-store 00:00 Introduction to The Downsized 00:46 Meet Al Maloney: Statistician and App Developer 02:31 The Concept of Personalized Dosing 03:52 Exploring the Weight Trekker App 05:55 Laraine's Weight Loss Journey with Mounjaro 09:37 Predicting Weight Loss with Weight Trekker 19:36 App Features and User Experience 29:31 Conclusion and App Availability

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Das Streben nach einem gesunden Gewicht ist für viele Menschen ein wichtiges Ziel. Ob aus gesundheitlichen Gründen oder um sich wohler im eigenen Körper zu fühlen – abnehmen kann auf verschiedene Weisen geschehen. Gesundes Abnehmen ist dabei nicht nur eine Frage der Ästhetik, sondern vor allem auch der Gesundheit. Es geht darum, den Körper mit allen notwendigen Nährstoffen zu versorgen und gleichzeitig überschüssiges Fett zu verlieren. In diesem Artikel werden verschiedene Methoden und Vorgehensweisen vorgestellt, die beim gesunden Abnehmen helfen können.

Die Bedeutung einer gesunden Ernährung

Eine gesunde Ernährung spielt eine entscheidende Rolle beim Abnehmen. Statt auf radikale Diäten zu setzen, die den Körper nur schwächen und langfristig keinen Erfolg bringen, ist es wichtig, auf eine ausgewogene Ernährung zu achten. Das bedeutet, dass man auf eine Vielzahl von Lebensmitteln setzt, die reich an Vitaminen, Mineralstoffen und Ballaststoffen sind. Obst, Gemüse, Vollkornprodukte und mageres Eiweiß sollten in ausreichender Menge auf dem Speiseplan stehen. Zudem ist es wichtig, ausreichend Flüssigkeit in Form von Wasser zu sich zu nehmen, um den Stoffwechsel zu unterstützen und Giftstoffe auszuschwemmen.

Des Weiteren ist es ratsam, auf stark verarbeitete Lebensmittel, Fertiggerichte und Fast Food zu verzichten. Diese enthalten oft zu viel Zucker, Salz und ungesunde Fette, die dem Körper nicht guttun und das Abnehmen erschweren können. Stattdessen sollte man auf frische, natürliche Lebensmittel setzen und selbst kochen, um die Kontrolle über die Zutaten zu behalten und gesund zu bleiben.

Bewegung als wichtiger Bestandteil

Neben einer gesunden Ernährung ist Bewegung ein weiterer wichtiger Bestandteil beim Abnehmen. Sport und körperliche Aktivitäten helfen dabei, Kalorien zu verbrennen, die Muskulatur aufzubauen und den Stoffwechsel anzukurbeln. Dabei ist es wichtig, eine Bewegungsform zu finden, die Spaß macht und sich gut in den Alltag integrieren lässt. Das kann zum Beispiel Joggen, Schwimmen, Radfahren oder Yoga sein. Auch kleine Veränderungen im Alltag, wie Treppensteigen statt Aufzugfahren oder Spaziergänge in der Natur, können dazu beitragen, mehr Bewegung in den Tagesablauf zu bringen.

Regelmäßige Bewegung nicht nur hilft beim Abnehmen, sondern auch dabei, sich fitter und vitaler zu fühlen. Sie fördert die Durchblutung, stärkt das Herz-Kreislauf-System, verbessert die Kondition und trägt dazu bei, Stress abzubauen und besser zu schlafen. Ein Mix aus Ausdauer-, Kraft- und Beweglichkeitstraining ist ideal, um Körper und Geist in Balance zu halten und langfristig gesund abzunehmen.

Tipps für ein erfolgreiches Abnehmen

Beim gesunden Abnehmen gibt es einige Tipps und Tricks, die helfen können, das Ziel zu erreichen und langfristig das Wunschgewicht zu halten. Dazu gehört neben einer gesunden Ernährung und ausreichend Bewegung auch das Setzen realistischer Ziele. Wichtig ist, geduldig zu sein und nicht zu schnell zu viel zu erwarten. Es braucht Zeit, um den Körper langsam und nachhaltig zu verändern. Kleine Schritte in die richtige Richtung sind oft effektiver als große Sprünge, die schwer umzusetzen sind.

Zudem ist es hilfreich, sich selbst zu reflektieren und auf die eigenen Bedürfnisse zu achten. Emotionales Essen, Stress oder Langeweile können oft Auslöser für ungesunde Essgewohnheiten sein. Es ist wichtig, diese Faktoren zu erkennen und alternative Strategien zu finden, um damit umzugehen. Ein Tagebuch zu führen, sich regelmäßig zu wiegen oder mit Freunden über die Fortschritte zu sprechen, können dabei unterstützen, am Ball zu bleiben und sich nicht entmutigen zu lassen.

Professional Unterstützung in Anspruch nehmen

Manchmal kann es hilfreich sein, professionelle Unterstützung in Anspruch zu nehmen, um beim gesunden Abnehmen erfolgreich zu sein. Ernährungsberater, Personal Trainer oder Psychologen können dabei helfen, individuelle Schwierigkeiten zu identifizieren und gezielte Lösungsansätze zu entwickeln. Sie bieten nicht nur fachliche Expertise, sondern auch Motivation und Unterstützung auf dem Weg zum Ziel.

Auch der Austausch mit Gleichgesinnten in Selbsthilfegruppen oder Online-Foren kann dabei helfen, sich gegenseitig zu motivieren und Erfahrungen auszutauschen. Man ist nicht alleine mit seinen Herausforderungen und kann von den Erfahrungen anderer profitieren. Das Gefühl, gemeinsam an einem Ziel zu arbeiten, kann dabei helfen, die Motivation hochzuhalten und am Ball zu bleiben, auch wenn es mal schwierig wird.

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Gesund abnehmen bedeutet, den Körper ganzheitlich zu betrachten und auf eine ausgewogene Ernährung, ausreichend Bewegung und mentale Balance zu achten. Es ist wichtig, geduldig zu sein, realistische Ziele zu setzen und sich nicht von Rückschlägen entmutigen zu lassen. Mit der richtigen Methoden und Vorgehensweisen, sowie der Unterstützung von Profis und Gleichgesinnten, kann jeder erfolgreich sein Wunschgewicht erreichen und langfristig halten. Es braucht Zeit und Engagement, aber die Ergebnisse sind es wert, für die eigene Gesundheit und das Wohlbefinden zu investieren.

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In terms of losing weight we are always looking for the easy way to do something or the quick fix that works everytime. We might agree that the best way to lose weight is by eating right and exercise but weight-loss pills and capsules appear to be the quick and easy way to ‘lose’ all those excess pounds. This is marketed as cutting out the exercise and still having a quick weight-loss. But are these pills making some great promises that are difficult to believe?

Exploring Weight Loss Pills Without Exercise

For people who want to lose weight without any effort, one option has always been weight loss pills. The active ingredient can be either an appetite suppressant that inhibits hunger, or a metabolism booster that accelerates the conversion of food into energy. Other pills might ‘catabolise’ fat or carbohydrates so that food is expelled from the body as waste instead of converted into fat.

Some people would love to simply fill a prescription and have the pounds shed off, but the reality can be more complex since many weight loss drugs have side effects, both minor and major, which include feeling nauseous, diarrhoea or headaches, or, worse, can cause heart palpitations, high blood pressure or liver damage.

Also, since weight loss pills are not regulated by the US Food and Drug Association (FDA), they don’t need to come with a guarantee that they’ll work, nor can you be certain that they won’t have harmful effects. While some of these pills may work, they could also be dangerous. For instance, some pills might not contain the advertised contents, or they could react differently in the body than anticipated. Whatever the specific issue, without regulation, it’s difficult to prescribe a weight loss pill that is safe to use.

The Importance of a Balanced Approach

In contrast, many so called ‘underground’ weight loss pills. can give you the pound-losses, but you can’t keep them for very long. So a healthy diet and a decent amount of exercise is what you need to lose the weight and maintain it. This will have benefits not only for your weight, but for your health and general well-being.

The fact still remains that weight loss takes time and effort, and is much more likely to be achieved only by making other adjustments in your lifestyle – which will have additional benefits for your general health. Healthy eating and regular physical activity are the keys to successful, long-term weight loss.

Making Informed Decisions

Unless you research your options or talk to a healthcare provider, there’s no guarantee that what you’re taking actually works – or that it’s safe. Weight-loss products are among the trickiest to navigate in the supplement arena – and there are plenty of safer ways to lose weight, if that’s your goal. In the end, shortcuts aren’t the answer. The most sustainable way to shed pounds is to adopt a lifestyle of healthy eating, regular exercise and wellness – and to steer way clear of weight-loss pills.

You may not achieve ideal weight, but you can make important healthful and mindful changes for the long term. Do weight loss pills help jump-start you on the path to better health? Absolutely. But they are no substitute for healthy living. Persevere and you can lose weight without pills or dreams.

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As women approach their mid to late thirties, they often suffer symptoms that are ignored or dismissed by conventional medicine. Insomnia, weight gain, irritability, reduced memory, and brain fog are all symptoms that can drastically change the quality of life for women. Today’s guest is here to show us that there is hope and that it doesn’t have to be this way. Today on The Dhru Purohit Podcast, Dhru sits down with Dr. Sara Gottfried for a deep dive into women’s health, specifically the changes that occur in perimenopause and menopause. Dr. Gottfried shares the symptoms women in these categories face and the science behind why they occur. She shows us the critical tests that need to be addressed, offers practical tips women can implement to address these changes and balance key hormones, and inspires women to empower themselves on their road to longevity. Dr. Sara Gottfried is a board-certified physician who graduated from Harvard and MIT. She practices evidence-based integrative, precision, and Functional Medicine. She is a Clinical Assistant Professor in the Department of Integrative Medicine and Nutritional Sciences at Thomas Jefferson University and Director of Precision Medicine at the Marcus Institute of Integrative Health. Her three New York Times bestselling books include The Hormone Cure, The Hormone Reset Diet, and Younger. Her latest book is Women, Food, and Hormones. In this episode, Dhru and Dr. Gottfried dive into: -The metabolic crisis that women in their 40s go through and the hope that Dr. Gottfried offers on a different way to be and live -How conventional medicine often dismisses the symptoms that women feel and makes them feel it's a normal part of aging -The top misconceptions or misunderstandings about the interplay between hormones, including how long before menopause symptoms can start -Women with high cortisol levels in their 40s had decreased brain volume and memory -Common symptoms of perimenopause and menopause as they relate to aging: mood swings, depression, insomnia, and loss of libido -The environmental and lifestyle factors that impact women’s hormones including stress, ultra-processed foods, and exposure to endocrine disrupters -The top 3 hormones to balance and correct: cortisol, estrogen, and thyroid -The importance of testosterone as the most abundant hormone in women’s bodies -How Dr. Gottfried started her hormonal journey by testing her cortisol and how prioritizing meditation and yoga reduced her stress response -Dealing with insomnia during perimenopause when it’s especially critical to prioritize sleep and how progesterone can help -Testing thyroid levels at least once a year and the connection between thyroid and autoimmune disease -Bringing hormones in harmony by increasing protein, reducing ultra-processed foods, increasing fiber, and quality fat -The key to feeling better in menopause is measuring and addressing your glucose levels -What drives belly fat and the relationship between belly fat and cortisol -Micronutrients, including Vitamin D and copper, and how they impact thyroid levels -The role of post-traumatic stress and the use of psychedelics -Helping women over 40 and the importance of healing states of consciousness -Dr. Gottfried’s message of how it doesn’t have to be this way Also mentioned in this episode: -The Charlie’s Angels of Hormones graphic: https://saragottfriedmd.com/dev/wp-content/uploads/2014/04/TTHC-W2-Charlies-Angels-Hormones-Handout.pdf -Levels: https://www.levelshealth.com/join?partner=DHRU -Dr. Gottfried’s book Women, Food, and Hormones: https://a.co/d/dUZPEL9 -Dr. Gottfried’s book The Hormone Cure: https://a.co/d/gIx6wQn For more on Dr. Sara Gottfried: -Instagram @saragottfriedmd -Facebook @drgottfried -Twitter @DrGottfried -YouTube @drgottfried -Website: https://saragottfriedmd.com This episode is brought to you by: -JOOVV: https://Joovv.com/dhru -LMNT: https://DrinkLMNT.com/dhru -Armra Colostrum: https://tryarmra.com/DHRU Right now, Joovv is offering an exclusive offer on your first order. Head over to https://Joovv.com/dhru and apply my code DHRU. Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to https://DrinkLMNT.com/dhru today. Receive 15% off your first order of Armra Colostrum at https://tryarmra.com/DHRU, or enter DHRU to get 15% off your first order.