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Drs Akshay Jain and Girish Joshi discuss clinical considerations to keep in mind when someone on GLP-1 therapy is undergoing elective procedures. https://www.medscape.com/viewarticle/glp-1-guidance-reduce-regurgitation-and-aspiration-risk-2024a1000d35?src=soc_yt -- TRANSCRIPT -- Akshay B. Jain, MD: Welcome back to ADA 2024 updates. I'm endocrinologist Dr Akshay Jain from Vancouver in Canada, and today we've got a very special guest. We've got Professor Dr Girish Joshi. Dr Joshi is a professor of anesthesiology and pain medicine at UT Southwestern in Dallas, Texas. He was one of the speakers at a very impactful session that was talking about the postoperative and intraoperative considerations for people who are on GLP-1 therapy. He's here to talk with us about clinical considerations that one needs to keep in mind when someone on glucagon-like peptide 1 (GLP-1) receptor agonist therapy is undergoing elective procedures. Welcome, Dr Joshi. Girish P. Joshi, MD: Thank you, Akshay. It's an honor. Jain: I was attending your session, and I found it very clinically impactful. This is something that we are seeing more and more in clinical practice. For our viewers today, can you share with us, as an anesthesiologist, the potential risks for aspiration and the rates of aspiration that you're seeing in people who are on GLP-1 therapy? Joshi: We don't know the exact rate of aspiration with GLP-1 therapy because there are no good studies, but there are several anecdotal reports, including several personal communications where people have contacted me and the American Society of Anesthesiologists (ASA). I'm the chair of the task force for these GLP-1 recommendations developed by the ASA. To give an example, one of the cases reported to me was from a colleague in Dallas where a patient, otherwise completely healthy, came in for a shoulder arthroscopy — a simple outpatient procedure in a freestanding ambulatory surgery center. Surgery went fine. At the end of the procedure, she regurgitated gastric content and aspirated, and then had to be taken to the intensive care unit (ICU) and she spent 7 days in the ICU. Retrospectively, it was recognized that she was on GLP-1 therapy for weight loss, which was not disclosed. This was just before the ASA came up with the guidance, basically, so people didn't know that GLP-1 receptor agonists do increase the risk for aspiration. Jain: That's a really good point straight from your clinical practice. For our viewers who may not be familiar with the guidelines, could you tell us, in a nutshell, for people on GLP-1 therapy who are going in for an elective procedure that requires general anesthesia, what would be the recommendations for holding GLP-1s? Joshi: I have to first emphasize that currently, the evidence to provide any guidance is sparse, and whatever studies are available are basically questionable or of poor quality. With that said, the reason why the ASA came up with the guidance was to inform our colleagues, anesthesiologists, as well as our colleagues from surgery and other proceduralists of this concern about increased regurgitation and aspiration in patients on GLP-1 receptor agonists. That was the primary aim. Because the evidence is sparse, we basically came up with different approaches to decrease or mitigate the risk for regurgitation and aspiration. It starts with having a collaborative discussion, including the patients, or shared decision-making with the physicians and the patient regarding the potential risks, so mention to the patient that there is a potential risk. Then, avoid the elective procedures in patients at high risk. Examples of patients at high risk would be those who are basically in the escalation phase of the GLP-1 therapy, patients with prior history of gastroparesis, or patients on drugs that can cause gastroparesis. I don't know whether you remember I had an algorithm I developed and presented at the American Diabetes Association (ADA) meeting, where I presented the potential risk factors. If the patients are at risk for regurgitation and aspiration, that's the patient population we've got to be extra careful with. Maybe start off withholding the drug if the patients are on, say, a weekly therapy, then 1 week before, though the evidence is minimal. Nevertheless, more importantly, avoid elective procedures during that escalation phase in this patient population. Transcript in its entirety can be found by clicking here: https://www.medscape.com/viewarticle/glp-1-guidance-reduce-regurgitation-and-aspiration-risk-2024a1000d35?src=soc_yt

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In this video, I talk why you should never talk Ozempic or any other GLP-1 drugs. I discuss the hidden dangers of GLP-1 drugs and what GLP-1 drugs really reveal about our food system. I also talk about what happens when you stop taking Ozempic. I give you the Carnivore alternative - how the human body regulates hunger and satiety naturally. Follow me on Instagram: username- @Sam_HyMD Medical Disclaimer: The content in this video is for educational and informational purposes only and is not intended as medical advice. The carnivore diet may not be suitable for everyone. Always consult with a qualified healthcare provider or your physician before making any changes to your diet, especially if you have a medical condition, are pregnant, nursing, taking medications, or have specific dietary needs. The creator of this video assumes no responsibility for the use or misuse of the information presented. Reliance on any information provided herein is solely at your own risk.

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Hey, hey! Welcome to my channel! How to lose weight without extreme diets? Yes, you can – without starving! Here is Day 3 !! If you're thinking about trying this diet, I hope my experience helps you! And yes, I admit… I did cheat a little 😅 But it still worked for me! I’ll be sharing daily meal ideas to keep you inspired and make it easier to stay motivated. What will you choose? Let’s find out together! I’d love to hear your thoughts in the comments – have you tried this diet too? Don’t forget to like, subscribe, and hit the notification bell so you won’t miss my next videos!

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Die optimale Proteinzufuhr spielt eine wichtige Rolle beim effektiven Abnehmen. Proteine sind essenzielle Nährstoffe, die beim Muskelaufbau helfen, den Stoffwechsel anregen und das Sättigungsgefühl fördern. Viele Menschen, die abnehmen möchten, neigen dazu, ihre Proteinzufuhr zu vernachlässigen. Doch eine ausreichende und qualitativ hochwertige Proteinversorgung ist entscheidend, um den Gewichtsverlust langfristig zu unterstützen.

Warum Proteine wichtig sind fürs Abnehmen

Proteine sind die Bausteine des Lebens und spielen eine entscheidende Rolle in unserem Körper. Sie sind nicht nur wichtig für den Muskelaufbau, sondern auch für die Regulierung des Blutzuckerspiegels, die Unterstützung des Immunsystems und die Verbrennung von Fett. Durch eine ausgewogene Proteinzufuhr kann der Körper effizienter Kalorien verbrennen und den Stoffwechsel ankurbeln.

Proteine sind zudem besonders sättigend und können dabei helfen, Heißhungerattacken zu vermeiden. Indem sie den Blutzuckerspiegel stabilisieren, tragen Proteine dazu bei, dass man sich länger satt und energiegeladener fühlt. Dies wiederum hilft, die Gesamtkalorienzufuhr zu reduzieren und somit das Abnehmen zu erleichtern.

Des Weiteren benötigt der Körper mehr Energie, um Proteine zu verdauen, als für die Verarbeitung von Kohlenhydraten oder Fetten. Dieser sogenannte thermische Effekt der Nahrung kann dazu beitragen, den Kalorienverbrauch zu steigern und somit den Gewichtsverlust zu unterstützen.

Wie viel Protein sollte man für effektives Abnehmen konsumieren

Die optimale Proteinzufuhr für effektives Abnehmen hängt von verschiedenen Faktoren wie dem Geschlecht, dem Alter, dem Gewicht und dem Aktivitätsniveau ab. Allgemein wird empfohlen, etwa 1,2 bis 2 Gramm Protein pro Kilogramm Körpergewicht zu konsumieren. Bei intensivem Training oder reduzierter Kalorienzufuhr kann der Proteinbedarf sogar höher sein.

Es ist wichtig, qualitativ hochwertige Proteinquellen zu wählen, die alle essenziellen Aminosäuren enthalten. Dazu gehören beispielsweise Fleisch, Fisch, Eier, Milchprodukte, Hülsenfrüchte, Nüsse und Samen. Eine gute Mischung aus tierischen und pflanzlichen Proteinen kann sicherstellen, dass man alle notwendigen Nährstoffe erhält.

Es ist auch ratsam, die Proteinaufnahme über den Tag zu verteilen und proteinreiche Mahlzeiten und Snacks einzubauen. Dies hilft dabei, den Muskelaufbau zu unterstützen, den Stoffwechsel anzukurbeln und das Sättigungsgefühl zu fördern. Eine ausgewogene Ernährung mit ausreichend Proteinen ist entscheidend für ein erfolgreiches Abnehmen.

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Um sicherzustellen, dass man genügend Proteine für ein effektives Abnehmen konsumiert, kann es hilfreich sein, Mahlzeiten und Snacks im Voraus zu planen. Proteinshakes oder -riegel können eine praktische und schnelle Option sein, um den Proteinbedarf zu decken, insbesondere nach dem Training oder unterwegs.

Auch das Kombinieren von Proteinen mit Ballaststoffen, gesunden Fetten und komplexen Kohlenhydraten kann dazu beitragen, den Blutzuckerspiegel stabil zu halten und das Sättigungsgefühl zu verlängern. Eine ausgewogene Ernährung mit verschiedenen Nährstoffen ist entscheidend für ein nachhaltiges und gesundes Abnehmen.

Es ist ratsam, ausreichend zu trinken, um den Stoffwechsel anzukurbeln und die Ausscheidung von Abfallstoffen zu unterstützen. Wasser ist der beste Durstlöscher und kann dabei helfen, den Appetit zu kontrollieren und den Kalorienverbrauch zu steigern.

Proteine als Teil eines gesunden Abnehmplans

Proteine allein sind kein Wundermittel zum Abnehmen, sondern sollten als Teil eines gesamten Ernährungs- und Fitnessplans betrachtet werden. Eine ausgewogene Ernährung mit einem moderaten Kaloriendefizit, regelmäßiger Bewegung und ausreichendem Schlaf sind entscheidend für einen erfolgreichen Gewichtsverlust.

Es ist wichtig, realistische Ziele zu setzen und geduldig zu sein, da nachhaltiges Abnehmen Zeit und Engagement erfordert. Indem man die Proteinzufuhr optimiert und einen gesunden Lebensstil pflegt, kann man sein Wunschgewicht erreichen und langfristig halten.

Denken Sie daran, dass jeder Körper individuell ist und verschiedene Bedürfnisse hat. Wenn Sie unsicher sind, wie Sie Ihre Proteinzufuhr optimieren können, konsultieren Sie am besten einen Ernährungsberater oder einen Arzt, um maßgeschneiderte Empfehlungen zu erhalten.

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When it comes to weight loss, many individuals struggle to find a solution that works for them. From fad diets to intense workout regimens, the options can seem overwhelming. However, one medication that has gained attention in recent years for its effectiveness in helping with weight loss is Semaglutide. Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that was originally developed to help manage diabetes. However, studies have shown that it can also be beneficial for individuals looking to lose weight.

How Semaglutide Works

Semaglutide works by mimicking the effects of GLP-1, a hormone that is produced in the gut. GLP-1 is released in response to food intake and helps regulate blood sugar levels by stimulating insulin release and reducing glucagon secretion. In addition to its effects on blood sugar, GLP-1 also helps reduce appetite and food intake. By taking Semaglutide, individuals can experience reduced feelings of hunger, leading to decreased caloric intake and, ultimately, weight loss.

In addition to its effects on appetite, Semaglutide also slows down gastric emptying, which can help individuals feel fuller for longer periods. This can lead to reduced snacking and overall lower calorie consumption. The combination of decreased appetite and delayed gastric emptying makes Semaglutide a powerful tool for weight loss.

Typical Average Weight Loss

Studies have shown that individuals taking Semaglutide for weight management can experience significant weight loss compared to those taking a placebo. The amount of weight loss can vary depending on the individual and other factors such as diet and exercise. However, on average, individuals taking Semaglutide can expect to lose around 15-20% of their body weight over the course of a year.

It’s important to note that results may vary, and not everyone will experience the same level of weight loss. Some individuals may see greater weight loss, while others may see less. Factors such as adherence to the medication, diet, and exercise habits can all impact the outcomes of Semaglutide for weight loss.

Potential Side Effects

Like any medication, Semaglutide can cause side effects in some individuals. Common side effects of Semaglutide include nausea, vomiting, diarrhea, and constipation. These side effects are usually mild and subside over time as the body adjusts to the medication. In rare cases, more serious side effects such as pancreatitis or allergic reactions may occur. It’s important to talk to your healthcare provider before starting Semaglutide to discuss any potential risks and benefits.

If you experience severe or persistent side effects while taking Semaglutide, it’s important to contact your healthcare provider immediately. They can help determine the best course of action and may recommend adjusting your dosage or discontinuing the medication if needed.

Conclusion

Semaglutide is a promising option for individuals looking to lose weight and improve their overall health. With its ability to reduce appetite, slow gastric emptying, and promote weight loss, Semaglutide can be a powerful tool in achieving weight loss goals. However, it’s important to remember that Semaglutide is not a magic solution and should be used in conjunction with a healthy diet and regular exercise for maximum results. Talk to your healthcare provider to see if Semaglutide may be right for you and to discuss any potential risks or side effects.

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This video is a tag along journey through weight loss with Zepbound. I hope these videos help somebody out there who is thinking about embarking on a weight loss journey or is currently on one. In this video, "Zepbound GLP-1 Journey: What I Eat for Dinner – Avocado & Tomato Tostada (NO TORTILLA)," join me as I share a delicious and healthy dinner recipe that's both light and satisfying. I’ll walk you through a unique twist on a tostada – without the traditional tortilla – featuring fresh avocado, juicy tomatoes, and flavorful toppings. This dish fits perfectly into my Zepbound GLP-1 journey, offering a nutritious, low-carb alternative that's as tasty as it is nourishing. Watch to see how easy it is to make and enjoy a healthy, guilt-free meal! #recipe #zepbound #mounjaro #ozempic #weightlossjourney2025 #weightlossbreakfast #glp1forweightloss #semaglutideforweightloss #semaglutide #glp1medication #highprotein #lowcarb #bellpeppers #onions #caloriedeficit #lowcaloriediet #lowcaloriemeals #cheddarcheese #avocado

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Celebrities have long held a tremendous amount of influence over the general public. Fans often look to their favorite celebrities for guidance on everything from fashion trends to workout routines. In recent years, this influence has extended to the realm of health and wellness as well. One such example of this is Oprah Winfrey’s endorsement of Keto Gummies. Keto Gummies Oprah: The Influence of Celebrity Endorsement explores the impact that celebrity endorsements, especially from someone as influential as Oprah Winfrey, can have on the popularity and success of a product.

The Power of Celebrity Endorsements

Celebrity endorsements have been a marketing strategy used by brands for decades. When a well-known figure promotes a product, it can significantly boost its sales and public perception. According to a study published in the Journal of Advertising, celebrity endorsements can create a positive brand image, increase brand awareness, and generate more sales. This is because consumers often trust the recommendations of celebrities they admire and are more likely to try a product or service if it has been endorsed by someone they admire.

When Oprah Winfrey announced that she was a fan of Keto Gummies, it was like striking gold for the brand. Oprah’s seal of approval instantly gave the product credibility and trustworthiness in the eyes of consumers. Her huge fan base, comprising millions of followers, were eager to try the product themselves, leading to a surge in demand for Keto Gummies. In this way, celebrity endorsements can drive sales and help a product gain widespread popularity in a short amount of time.

It’s not just about the immediate impact either. Celebrity endorsements can also have a lasting effect on a brand’s reputation. When a celebrity consistently promotes and uses a product, it establishes a long-term association between the two in the minds of consumers. For example, Oprah Winfrey has been associated with various health and wellness products over the years, and her endorsement of Keto Gummies only adds to her reputation as a trusted authority in the industry.

The Oprah Effect on Keto Gummies

So, what exactly are Keto Gummies and why did Oprah Winfrey’s endorsement make such a big impact on their popularity? Keto Gummies are a type of dietary supplement that are specially formulated to support a ketogenic lifestyle. They are made with natural ingredients like BHB (beta-hydroxybutyrate) to help the body enter ketosis more quickly and easily. This means that Keto Gummies can potentially help individuals following a keto diet burn fat more efficiently for energy, leading to weight loss and other health benefits.

When Oprah Winfrey shared her love for Keto Gummies with her audience, it brought attention to the product’s potential benefits for weight loss and overall health. Her fans saw her as a credible source of information on health and wellness, so they were more inclined to trust her recommendation. As a result, many people who were on the fence about trying Keto Gummies decided to give them a chance, leading to a surge in sales and popularity for the brand.

Furthermore, Oprah’s endorsement of Keto Gummies helped bring awareness to the ketogenic diet and its benefits. The diet has been gaining popularity in recent years for its potential to promote weight loss and improve overall health. By shining a spotlight on Keto Gummies, Oprah helped educate her followers about the benefits of a ketogenic lifestyle and encouraged them to explore new ways to support their health and wellness goals.

The Future of Celebrity Endorsements

Celebrity endorsements are likely to continue playing a significant role in shaping consumer behavior and influencing purchasing decisions. In the age of social media, celebrities have more platforms than ever to connect with their fans and promote products they believe in. As a result, brands are increasingly turning to celebrity endorsements as a way to reach a wider audience and establish credibility for their products.

However, it’s important for consumers to approach celebrity endorsements with a critical eye. While celebrities may genuinely believe in the products they promote, not all endorsements are based on scientific evidence or expert opinions. It’s essential for consumers to do their research and consult with healthcare professionals before trying any new health or wellness product, even if it has been endorsed by a celebrity they admire.

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In conclusion, Oprah Winfrey’s endorsement of Keto Gummies is a prime example of the power of celebrity influence in the health and wellness industry. Her seal of approval helped boost the brand’s popularity and brought awareness to the benefits of a ketogenic lifestyle. As celebrity endorsements continue to shape consumer behavior, it’s important for consumers to be informed and make educated decisions about the products they choose to support.

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