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Unboxing Biotech Presents Lexaria Bioscience (LEXX). This short features CEO Chris Bunka who enumerates the primary takeaways from the GLP-1 agonist human pilot study. See other videos in the series: Lexaria's Successful GLP-1 Agonist Pilot Study https://youtu.be/rZ-fP8W5L_I Lexaria's IND for DehydraTECH CBD Cleared by FDA https://youtu.be/zINWWZ-q67Y Lexaria's GLP-1 Agonist Human Pilot Study https://youtu.be/OuDXyoh-JgI Lexaria's Upcoming GLP-1 Agonist Studies https://youtu.be/zy5dbFe6goE Lexaria's Hypertension Program Explained https://youtu.be/ClgG2JHZxmo Fireside Chat Lights Into Lexaria's DehydraTECH https://youtu.be/UqUwbA1evk4 What Did We Learn From Lexaria' GLP-1 Study? https://youtu.be/ruMzbPukdno Three Takeaways from Lexaria's Semaglutide Study https://youtu.be/-bTpluj4RjM See the company's presentation and further disclosures in the March 2024 presentation: https://d1io3yog0oux5.cloudfront.net/_f504402c500e6b4a8e4f3dcbe98624bd/lexariabioscience/db/932/8504/pdf/2024-03+LEXX+Lexaria+Presentation.pdf

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Another lecture in IHMC's award winning lecture series. http://www.ihmc.us There is growing awareness that the profound changes in the environment (e.g. in diet and other lifestyle conditions) that began with the introduction of agriculture and animal husbandry approximately 10,000 years ago occurred too recently on an evolutionary timescale for the human genome to adjust. In conjunction with this discordance between our ancient, genetically-determined biology and the nutritional, cultural and activity patterns of contemporary western populations, many of the so-called diseases of civilization have emerged. In the U.S. and most western countries, diet-related chronic diseases represent the single largest cause of morbidity and mortality. These diseases are epidemic in contemporary, westernized populations and typically afflict 50-65 % of the adult population, yet are rare or non-existent in hunter-gatherers and other less westernized people. Evidence gleaned over the past three decades now indicates that virtually all so-called diseases of civilization have multifactorial dietary elements that underlie their etiology, along with other environmental agents and genetic susceptibility. This talk will trace the origins of the Western diet and discuss the health implications. Dr. Cordain is a Professor in the Department of Health and Exercise Science at Colorado State University in Fort Collins, Colorado. His research emphasis over the past 15 years has focused upon the evolutionary and anthropological basis for diet, health and well being in modern humans. Dr. Cordain's scientific publications have examined the nutritional characteristics of worldwide hunter-gatherer diets as well as the nutrient composition of wild plant and animal foods consumed by foraging humans. Over the past five years his work has focused upon the adverse health effects of the high dietary glycemic load that is ubiquitous in the typical western diet. A number of his recent papers have proposed an endocrine link between dietary induced hyperinsulinemia and acne. Currently, Dr. Cordain's research team is exploring the connection between dietary elements that increase intestinal permeability (primarily saponins and lectins) and autoimmune disease, particularly multiple sclerosis. Dr. Cordain is the author of more than 100 peer review publications, many of which were funded by both private and governmental agencies. He is the recent recipient of the Scholarly Excellence award at Colorado State University for his contributions into understanding optimal human nutrition. He has lectured extensively world wide, and has written three popular books (The Paleo Diet, John Wiley & Sons; The Paleo Diet for Athletes, Rodale Press; The Dietary Cure for Acne) summarizing his research findings.

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Cheat meals can help boost your fat loss results as opposed to hinder them. How? And how does The Rock incorporate his cheat meals? Well, first off and arguably most importantly is the psychological benefit having cheat meals while cutting provide. You’ll exhibit long-term adherence and enjoyment to your diet when you have these planned ‘refeed day’ to work towards in your workout meal plan and look forward to. Second, the temporary increase in calories and carbs by adding a cheat meal into your meal plan to get ripped has been shown to lead to better appetite suppression, higher energy expenditure, and increased performance in the following days. So how can you now go about incorporating cheat days into your plan properly? First, plan this cheat meal into your weekly diet. In my opinion, the best way to do this is by allocating one day of the week to be what’s called a re-feed day. This is simply a day where you take a “break” from your diet by now eating at your maintenance calories or at a slight surplus. If you wanted to really indulge, then you can make more room for it by eating a little less on the days leading up to it and saving most of your calories for it. That said, be aware of how quickly your calories can add up during your cheat meals. Next, let’s talk about the actual composition of your cheat meals. Compared to fat and protein, carbs not only have the greatest impact on boosting your leptin levels which as discussed earlier can help with appetite suppression and increasing your energy expenditure when dieting, but they will also best help refill your muscle glycogen to create more muscle fullness and potentially augment your performance and the anabolic response you experience in your following workouts. Also, in the event that you do splurge on your calories and overeat quite a bit, you’d save 0.1 lbs of fat from being put on for every lb of weight that you gain from overeating if you were to do so primarily with carbs, compared to fats. Interestingly, overeating with predominantly protein actually results in the least amount of added fat gain when compared to carbs and fats. Meaning that if you’re going to splurge and overeat, doing so with carbs and ideally protein-rich foods has the greatest likelihood of minimizing fat gain. And lastly, it’s important that you don’t turn your cheat meal into a cheat day, and then turn cheat days into a cheat week, and then fail to ever get back on track. To prevent this, take the word “cheat meal” out of your vocabulary. I use it in this video just because it’s a commonly understood term, but the very word itself has some negative connotations and guilt associated with it. Instead, name it a “planned indulgence” or “calculated splurge” or “celebration meal” for example, because it’s not a meal that you should feel bad or guilty about at all. Secondly, if all week you’re struggling with cravings and all you can think about is your upcoming cheat meal and “reward” for your diet, then what this implies is that your current diet just isn’t sustainable. You need to consider re-structuring your diet such that you’re not completely depriving yourself. Otherwise, you’re just setting yourself up for failure in the long run. Be strategic with your planned indulgences if you choose to include cheat meals while cutting, but enjoy yourselves and remember that at the end of the day what’s most important is the calorie deficit that you create over time and your long-term adherence to that. Which is why it’s vital that you set up your diet based on what will enable you to accomplish those two factors most effectively. And if you do get off track, don’t beat yourself up. Get back on the saddle and take it day by day. And for an easy to follow science based program that sets everything up for you, such that you know exactly how to train AND what to eat week after week without depriving yourself of the foods you love, so that you can lean down and burn off fat most effectively with science, then simply take the analysis quiz below to discover which specific program is best for you: https://builtwithscience.com/bws-free-fitness-quiz/gender?utm_source=Youtube&utm_medium=Video&utm_content=Description%20box&utm_campaign=Use%20cheat%20meals%20to%20lose%20fat%20faster%20Mar%208%2F2020 Filmed by: Bruno Martin Del Campo MUSIC: soundcloud.com/lakeyinspired STUDIES: PSYCHOLOGICAL BENEFIT https://www.sciencedirect.com/science/article/abs/pii/S1057740815000443 LONG-TERM DIETING EFFECTS https://www.ncbi.nlm.nih.gov/pubmed/26384657 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359485/ PHYSIOLOGICAL BENEFITS https://www.ncbi.nlm.nih.gov/pubmed/11126336 https://www.ncbi.nlm.nih.gov/pubmed/1258067 CALORIE ADD-UP https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740215/ HIGH CARB BENEFITS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359485/ https://www.ncbi.nlm.nih.gov/pubmed/7598063 HIGH PROTEIN BENEFIT https://www.ncbi.nlm.nih.gov/pubmed/657500

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